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Scientists create 3D images of unique RNA molecule critical for stem cell programming

Scientists at Los Alamos and international partners have created the first 3-D images of a special type of RNA molecule that is critical for stem cell programming and known as the "dark matter" of the genome.

10 Jan 2020

Study: Understanding second-degree burns is key to treating these complications

New research shows how second-degree burns cause hard-to-treat chronic pain, and this understanding may be key to treating these complications, common in war veterans.

10 Jan 2020

Scientists find way to combine two main coding languages into single 'bilingual' molecule

The nucleic acids of DNA encode genetic information, while the amino acids of proteins contain the code to turn that information into structures and functions. Together, they provide the two fundamental codes underlying all of life.

9 Jan 2020

Administering enzalutamide results in significant increase in PSMA density on tumor surface

When a non-scientist tries to imagine a scientist, the image that often arises is one of a somewhat remote, rather idealistic genius sitting alone in their room or laboratory and somehow discovering the most amazing things without every having contact with the 'normal' world.

9 Jan 2020

Smoking dormant HIV virus out into the open to develop a cure

Ever since antiretroviral treatments against HIV infection were introduced in 1996, scientists have eagerly been hunting for a cure for the disease.

9 Jan 2020

New screening platform helped scientists to discover drug-like compounds

A sophisticated new screening platform developed by scientists at Scripps Research has enabled them to discover a set of drug-like compounds, including an ingredient found in sore throat lozenges, that may powerfully protect brain cells from dangerous stresses found in Alzheimer's and other neurodegenerative diseases.

9 Jan 2020

SVC112 molecule acts specifically against head and neck cancer stem cells

The red, tube-shaped flowers of the firecracker bush (Bouvardia ternifolia), native to Mexico and the American Southwest, attract hummingbirds.

8 Jan 2020

Single-particle method helps determine isoelectric point of viruses

Viruses are not easy to characterize. But we need to because being able to quickly predict the surface charge of viruses opens up new possibilities for vaccine purification and making gene therapy treatments for eye diseases and muscular dystrophy.

8 Jan 2020

Researchers study the effects of antidepressants to identify the least harmful drugs

About one in ten women in Québec will suffer from depression during pregnancy. Without treatment, the illness carries risks for both mother and child.

8 Jan 2020

Persistent TB infection of macrophages puts the brakes on immune engines, study shows

Scientists from Trinity College Dublin have discovered both how TB puts the brakes on our immune engines and how we can kick-start those engines back into gear - providing hope that improved treatment options could soon be on the horizon.

8 Jan 2020

Two-drug combination could be effective against malignant mesothelioma

Exposure to asbestos is the major risk factor for malignant mesothelioma, a type of aggressive cancer that mostly affects the pleura - the tissue that lines the lungs - and the peritoneum - the tissue that lines the abdomen. This has been known for decades, yet the molecular characterisation of mesothelioma is barely known and treatment options are scarce.

8 Jan 2020

Extremely low concentrations of acetic acid could alter cellular processes in rice blast fungus

All living organisms respond and adapt to changes in their environment. These responses are sometimes so significant that they cause alterations in the internal metabolic cycles of the organism--a process called "metabolic switching." For example, rice blast fungus--a pathogenic fungal species that causes the "rice blast" infection in rice crops--switches to the "glyoxylate cycle" when the nutrient source starts to deplete.

8 Jan 2020

Researchers reveal how antibodies assemble to form a circle for defensive attack

Antibodies are key players in our immune system. These antibodies recognize antigens displayed on foreign cell membranes and thereby recruit attacking forces, called complements.

6 Jan 2020

Study may explain how chemicals in skincare products trigger allergic contact dermatitis

Allergic reactions in the skin can be caused by many different chemical compounds found in creams, cosmetics, and other topical consumer products, but how they trigger the reaction has remained somewhat mysterious.

3 Jan 2020

Bile acids could also play a role in immunity and inflammation

Could bile acids--the fat-dissolving juices churned out by the liver and gallbladder--also play a role in immunity and inflammation?

3 Jan 2020

Novel study on molecular interactions could make it easier to develop new medicines

A first-of-its-kind study on molecular interactions by biomedical engineers in the University of Minnesota's College of Science and Engineering will make it easier and more efficient for scientists to develop new medicines and other therapies for diseases such as cancer, HIV, and autoimmune diseases.

3 Jan 2020

Study reveals new way to predict risk of death for people with stable heart failure

A UCLA-led study revealed a new way to predict which patients with "stable" heart failure - those who have heart injury but do not require hospitalization - have a higher risk of dying within one to three years.

3 Jan 2020

Tau-protein better predicts brain atrophy in Alzheimer's patients than amyloid plaques

Brain imaging of pathological tau-protein "tangles" reliably predicts the location of future brain atrophy in Alzheimer's patients a year or more in advance, according to a new study by scientists at the UC San Francisco Memory and Aging Center. In contrast, the location of amyloid "plaques," which have been the focus of Alzheimer's research and drug development for decades, was found to be of little utility in predicting how damage would unfold as the disease progressed.

2 Jan 2020

A new deep learning approach to predict disease-associated mutations

During the past years, artificial intelligence (AI) -- the capability of a machine to mimic human behavior -- has become a key player in high-techs like drug development projects.

28 Dec 2019

A HSC surface marker plays key role in ontogeny of hematopoiesis

A group of researchers at Osaka University revealed that ESAM (Endothelial cell-selective adhesion molecule), a surface marker for hematopoietic stem cells (HSCs) and vascular endothelial cells (ECs), played an important role in the ontogeny of hematopoiesis in mice, particularly in the development of adult-type erythropoiesis.

26 Dec 2019

Molecule News and Research

Scientists create 3D images of unique RNA molecule critical for stem cell programming

Study: Understanding second-degree burns is key to treating these complications

Scientists find way to combine two main coding languages into single 'bilingual' molecule

Administering enzalutamide results in significant increase in PSMA density on tumor surface

Smoking dormant HIV virus out into the open to develop a cure

New screening platform helped scientists to discover drug-like compounds

SVC112 molecule acts specifically against head and neck cancer stem cells

Single-particle method helps determine isoelectric point of viruses

Researchers study the effects of antidepressants to identify the least harmful drugs

Persistent TB infection of macrophages puts the brakes on immune engines, study shows

Two-drug combination could be effective against malignant mesothelioma

Extremely low concentrations of acetic acid could alter cellular processes in rice blast fungus

Researchers reveal how antibodies assemble to form a circle for defensive attack

Study may explain how chemicals in skincare products trigger allergic contact dermatitis

Bile acids could also play a role in immunity and inflammation

Novel study on molecular interactions could make it easier to develop new medicines

Study reveals new way to predict risk of death for people with stable heart failure

Tau-protein better predicts brain atrophy in Alzheimer's patients than amyloid plaques

A new deep learning approach to predict disease-associated mutations

A HSC surface marker plays key role in ontogeny of hematopoiesis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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