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P. gingivalis could be a novel risk factor for esophageal cancer

University of Louisville School of Dentistry researchers have found a bacterial species responsible for gum disease, Porphyromonas gingivalis, is present in 61 percent of patients with esophageal squamous cell carcinoma (ESCC).

27 Feb 2016

Study examines sexual satisfaction of heterosexual couples in long-term relationships

A Chapman University psychologist and his interdisciplinary research team have just published a study examining the sexual satisfaction -- or dissatisfaction -- of heterosexual couples in long-term relationships, and what contributes to keeping sexual passion alive.

27 Feb 2016

EMA grants Orphan Drug Designation to venetoclax for treatment of acute myeloid leukemia

AbbVie, a global biopharmaceutical company, today announced the European Medicines Agency has granted Orphan Drug Designation to venetoclax, an investigational, oral B-cell lymphoma-2 (BCL-2) inhibitor, for the treatment of acute myeloid leukemia (AML).

26 Feb 2016

Rigel begins fostamatinib Phase 2 trial for treatment of patients with autoimmune hemolytic anemia

Rigel Pharmaceuticals Inc. today announced that it has initiated a Phase 2 clinical trial to evaluate fostamatinib, its oral SYK inhibitor, as a potential treatment for autoimmune hemolytic anemia (AIHA).

25 Feb 2016

Maraviroc drug safe, well-tolerated when taken as PrEP to prevent HIV infection

Maraviroc, an oral drug used to treat HIV infection, is safe and well-tolerated when taken daily as pre-exposure prophylaxis (PrEP) to prevent HIV infection by HIV-uninfected men who have sex with men (MSM) at increased risk for acquiring HIV.

25 Feb 2016

Ketamine appears to be safe, effective for difficult-to-sedate ER patients

For the small segment of the emergency population whose acute behavioral disturbance does not respond to traditional sedation, ketamine appears to be effective and safe, according to an Australian study published online last Thursday in Annals of Emergency Medicine ("Ketamine for Difficult to Sedate Severe Acute Behavioral Disturbance in the Emergency Department").

25 Feb 2016

This No Smoking Day think of your oral health and kick the habit

Europe’s largest dental treatment provider, mydentist, is calling on smokers across the UK to quit on No Smoking Day for the good of their oral health.

24 Feb 2016

ViiV Healthcare presents positive results from LATTE-2 study at CROI

ViiV Healthcare, the global specialist HIV company majority owned by GSK, with Pfizer Inc. and Shionogi Limited as shareholders, today presented positive results from the LATTE-2 study at the Conference on Retroviruses and Opportunistic Infections (CROI) in Boston. Headline results were announced in November 2015.

24 Feb 2016

Dapivirine ring can help prevent HIV-1 infection in women

In an important scientific achievement for women's health, two large Phase III clinical trials -- The Ring Study and ASPIRE -- have shown that a monthly vaginal ring containing the antiretroviral drug (ARV) dapivirine can safely help prevent HIV-1 infection in women.

23 Feb 2016

BetterYou urges importance of vitamin D for children as new research links breastfed youngsters to deficiency

Fresh research linking breastfed youngsters to vitamin D deficiency has again prompted health pioneers BetterYou to urge the importance of vitamin D supplementation for children.

From BetterYou Ltd 23 Feb 2016

PharmaEssentia to present results of P1101 + ribavirin phase II trial in HCV patients at APASL 2016

PharmaEssentia Corporation announces presentation of the results of the phase II trial for P1101 + ribavirin in patients with chronic HCV genotype 1 infection at the 25th Conference of the Asian Pacific Association for the Study of the Liver, taking place in Tokyo, Japan from February 20 to 24, 2016 (APASL 2016). Data will be presented by the study coordinating investigator Prof. Wan-Long Chuang (Taiwan) at the HCV parallel oral session on Feb 22nd (15:45-17:45).

22 Feb 2016

Differences in patient education level may compromise safety, efficacy of anticoagulants

Patients with no schooling benefit least from blood thinning medications, reveals a European Heart Rhythm Association / European Society of Cardiology survey published today in Europace.

22 Feb 2016

Naldemedine significantly improves opioid-induced constipation in patients with chronic non-cancer pain

Shionogi today announced pivotal phase III study (COMPOSE I) results showing that once-daily treatment with naldemedine significantly improved opioid-induced constipation (OIC) compared to placebo in patients with chronic non-cancer pain.

22 Feb 2016

Uninsured and Medicaid patients have higher overall and cancer-specific mortality rates

Compared to patients with non-Medicaid insurance, uninsured patients and patients with Medicaid are more likely to present with advanced stages of head and neck cancer and have higher overall and cancer-specific mortality rates, according to research presented at the 2016 Multidisciplinary Head and Neck Cancer Symposium.

19 Feb 2016

Patients with chronic kidney disease and periodontitis have higher mortality rate

New findings from the University of Birmingham show that patients with chronic kidney disease patients and periodontitis (severe gum disease) have a higher mortality rate than those with chronic kidney disease alone.

18 Feb 2016

Prolonged monitoring increases AF yield in stroke survivors

Another presentation at the International Stroke Conference today shows that prolonged periods of Holter-ECG monitoring markedly increase detection of paroxysmal atrial fibrillation in patients with stroke.

18 Feb 2016

Tackling insulin resistance may reduce recurrence after stroke

Giving pioglitazone to stroke survivors with insulin resistance but no overt diabetes reduces their risk of having a recurrent vascular event, shows the randomised Insulin Resistance Intervention after Stroke trial.

18 Feb 2016

American Pain Society releases new post-surgical pain management guideline

The American Pain Society has released a new evidence-based clinical practice guideline, appearing in The Journal of Pain, with 32 recommendations to help clinicians achieve optimal pain management following surgery. According to numerous studies, the majority of surgical patients receive inadequate pain relief, which can heighten the risk for prolonged post-surgical pain, mood disorders and physical impairment.

18 Feb 2016

Better understanding link between oral bacteria and certain types of stroke

In a study of patients entering the hospital for acute stroke, researchers have increased their understanding of an association between certain types of stroke and the presence of the oral bacteria (cnm-positive Streptococcus mutans).

17 Feb 2016

CTI BioPharma announces Q4 and FY 2015 earnings

CTI BioPharma Corp. today reported financial results for the fourth quarter and full year ended December 31, 2015.

17 Feb 2016

Oral News and Research

P. gingivalis could be a novel risk factor for esophageal cancer

Study examines sexual satisfaction of heterosexual couples in long-term relationships

EMA grants Orphan Drug Designation to venetoclax for treatment of acute myeloid leukemia

Rigel begins fostamatinib Phase 2 trial for treatment of patients with autoimmune hemolytic anemia

Maraviroc drug safe, well-tolerated when taken as PrEP to prevent HIV infection

Ketamine appears to be safe, effective for difficult-to-sedate ER patients

This No Smoking Day think of your oral health and kick the habit

ViiV Healthcare presents positive results from LATTE-2 study at CROI

Dapivirine ring can help prevent HIV-1 infection in women

BetterYou urges importance of vitamin D for children as new research links breastfed youngsters to deficiency

PharmaEssentia to present results of P1101 + ribavirin phase II trial in HCV patients at APASL 2016

Differences in patient education level may compromise safety, efficacy of anticoagulants

Naldemedine significantly improves opioid-induced constipation in patients with chronic non-cancer pain

Uninsured and Medicaid patients have higher overall and cancer-specific mortality rates

Patients with chronic kidney disease and periodontitis have higher mortality rate

Prolonged monitoring increases AF yield in stroke survivors

Tackling insulin resistance may reduce recurrence after stroke

American Pain Society releases new post-surgical pain management guideline

Better understanding link between oral bacteria and certain types of stroke

CTI BioPharma announces Q4 and FY 2015 earnings

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