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Real-world data validates gene therapy for spinal muscular atrophy

Findings from a new study in the Journal of Neuromuscular Diseases, published by IOS Press, demonstrate the effectiveness of disease-modifying treatments (DMTs) in infants with spinal muscular atrophy (SMA).

15 Apr 2024

Texas A&M scientists elucidate how phages disarm antibiotic-resistant bacteria

Bacterial infections pose significant challenges to agriculture and medicine, especially as cases of antibiotic-resistant bacteria continue to rise.

15 Apr 2024

Breakthrough brain stimulator could revolutionize treatment for neurological disorders

Rice University engineers have developed the smallest implantable brain stimulator demonstrated in a human patient.

15 Apr 2024

Can psychedelics improve sexual functioning and satisfaction?

The influence of psychedelics on sexual functioning.

15 Apr 2024

Study reveals how SARS-CoV-2 hijacks lung cells to drive COVID-19 severity

Researchers identified how SARS-CoV-2 targets and manipulates specific lung cells, using innovative techniques to trace the virus's impact on the cells' gene expression, revealing insights into early COVID-19 pathogenesis.

14 Apr 2024

Esketamine after childbirth cuts risk of postnatal depression by three-quarters

Low-dose esketamine administered post-labor significantly reduced depressive symptoms in women with prenatal depression within 42 days, despite an increase in short-lived neuropsychiatric side effects.

14 Apr 2024

Study reveals high prevalence of menstrual migraines in U.S. women

A third of the nearly 20 million women who participated in a national health survey report migraines during menstruation, and of them, 11.8 million, or 52.5%, were premenopausal.

13 Apr 2024

Breakthrough study reveals melanoma's resistance tactics to targeted therapy

Melanoma is the deadliest form of skin cancer. With global incidence rates rising, new, more effective treatments are necessary to alleviate the health burden of the disease. Important advances in recent years include doctors using genetic tests to look for specific mutations they can target for more personalised, effective treatment.

13 Apr 2024

Vosoritide's first phase 2 study shows increased growth in children with hypochondroplasia

Vosoritide's first global phase 2 study showed an average increased growth rate of 1.8 cm per year in children with hypochondroplasia, a genetic cause of short stature in children, according to researchers from Children's National Hospital.

13 Apr 2024

Wearable devices reveal stress-related changes during sleep

What if changes in a person's stress levels could be detected while they sleep using wearable devices? A new study by University of Vermont researchers published today in PLOS Digital Health is the first to find changes in perceived stress levels reflected in sleep data - an important step towards identifying biomarkers that may help flag individuals in need of support.

13 Apr 2024

Hypoglossal nerve stimulation offers hope for pediatric Down syndrome patients with OSA

While Obstructive Sleep Apnea (OSA) affects about five percent of the general pediatric population, 80 percent of children with Down syndrome experience OSA. Continual OSA results in poor health, including disruptions to cognitive development and functioning, leading physician-researchers from Mass General Brigham to investigate better methods to treat these patients as early as possible to maximize their health outcomes.

12 Apr 2024

Nearly 1 in 4 adults dumped from Medicaid are now uninsured, survey finds

Nearly a quarter of adults disenrolled from Medicaid in the past year say they are now uninsured, according to a survey released Friday that details how tens of millions of Americans struggled to retain coverage in the government insurance program for low-income people after pandemic-era protections began expiring last spring.

12 Apr 2024

Study provides valuable insights into the DCB-only strategy for left main coronary artery disease

Sanna Uskela et al., at North Karelia Central Hospital-Heart Center, Finland, conducted a retrospective single-center registry study that focused on the use of drug-coated balloon (DCB)-only strategy for treating de novo left main coronary artery disease.

12 Apr 2024

Study sheds light on how androgens shape sex differences at the cellular and molecular levels

Sex differences are widespread across human development, physiological processes, and diseases, making it important to characterize the impact of sex differences in these areas.

12 Apr 2024

Revolutionizing heart failure treatment: Advances in mechanical circulatory support devices

The same technology that enables a bullet train to travel at speeds up to 200 mph without touching its rails now keeps a failing heart pumping - and in the near future, it will do so via a wireless power connection.

12 Apr 2024

Transcranial direct current stimulation shows promise for treating depression, anxiety in older adults

A noninvasive brain stimulation treatment improved depression and anxiety symptoms among older adults in a new University of Florida-led study.

12 Apr 2024

Is psilocybin safe for treating depression and anxiety?

A study in JAMA Network Open examined the acute adverse effects of therapeutic doses of psilocybin for treating depression and anxiety, focusing on its safety profile by assessing the occurrence of immediate side effects like headache, nausea, and elevated blood pressure among others.

12 Apr 2024

Tumor microbiomes offer new insights for enhancing cancer therapies

Comprehensive review reveals the significant impact of tumor-resident bacteria on metastatic cancer, showing how microbiome genomes influence tumor biology, immune system response, and treatment effectiveness. It lays the groundwork for utilizing bacteria-focused therapies to complement traditional cancer treatments.

11 Apr 2024

New lab assay could make diagnosis and treatment of lung cancer easier

A new lab assay developed by researchers at Fred Hutch Cancer Center could make diagnosis and treatment of small-cell lung cancer and non-small cell lung cancer easier.

10 Apr 2024

Newly discovered genetic variant reduces the odds of developing Alzheimer's disease

Columbia researchers have discovered a genetic variant that reduces the odds of developing Alzheimer's disease by up to 70% and may be protecting thousands of people in the United States from the disease.

10 Apr 2024

Therapy News and Research

Real-world data validates gene therapy for spinal muscular atrophy

Texas A&M scientists elucidate how phages disarm antibiotic-resistant bacteria

Breakthrough brain stimulator could revolutionize treatment for neurological disorders

Can psychedelics improve sexual functioning and satisfaction?

Study reveals how SARS-CoV-2 hijacks lung cells to drive COVID-19 severity

Esketamine after childbirth cuts risk of postnatal depression by three-quarters

Study reveals high prevalence of menstrual migraines in U.S. women

Breakthrough study reveals melanoma's resistance tactics to targeted therapy

Vosoritide's first phase 2 study shows increased growth in children with hypochondroplasia

Wearable devices reveal stress-related changes during sleep

Hypoglossal nerve stimulation offers hope for pediatric Down syndrome patients with OSA

Nearly 1 in 4 adults dumped from Medicaid are now uninsured, survey finds

Study provides valuable insights into the DCB-only strategy for left main coronary artery disease

Study sheds light on how androgens shape sex differences at the cellular and molecular levels

Revolutionizing heart failure treatment: Advances in mechanical circulatory support devices

Transcranial direct current stimulation shows promise for treating depression, anxiety in older adults

Is psilocybin safe for treating depression and anxiety?

Tumor microbiomes offer new insights for enhancing cancer therapies

New lab assay could make diagnosis and treatment of lung cancer easier

Newly discovered genetic variant reduces the odds of developing Alzheimer's disease

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