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Finding may significantly broaden understanding of how the brain selects and retains information

By examining how sounds are registered during the process of learning, UC Irvine neurobiologists have discovered a neural coding mechanism that the brain relies upon to register the intensity of memories based on the importance of the experience.

12 Sep 2005

Microtubules critical to development of mental disorders

Neuroscientists at the University at Buffalo have shown in two recently published papers that destabilization of structures called microtubules, intracellular highways that transport receptors to their working sites in the brain, likely underlie many mental disorders and could be promising targets for intervention.

12 Sep 2005

Translation elongation factor eEF1A2 is is a potential oncogene that is overexpressed in two-thirds of breast tumors

The tissue-specific elongation factor eEF1A2 might be an oncoprotein involved in breast cancer.

12 Sep 2005

Clioquinol appears to block the genetic action of Huntington's disease

Clioquinol, an antibiotic that was banned for internal use in the United States in 1971 but is still used in topical applications, appears to block the genetic action of Huntington's disease in mice and in cell culture, according to a study reported by San Francisco VA Medical Center (SFVAMC) researchers.

12 Sep 2005

Sugar-coated markers of brain cell development may help success of stem cell transplants

Four sugar-coated faces made by stem cells as they differentiate into brain cells during development have been identified by scientists.

10 Sep 2005

Researchers discover discrete region of the monkey brain that processes pitch

Johns Hopkins researchers have discovered a discrete region of the monkey brain that processes pitch, the relative high and low points of sound, by recognizing a single musical note played by different instruments.

7 Sep 2005

Animal model of Parkinson's disease reveals striking sensitivity to common environmental toxins

In findings that support a relationship between agricultural chemicals and Parkinson's disease, two groups of researchers have found new evidence that loss of DJ-1, a gene known to be linked to inherited Parkinson's disease, leads to striking sensitivity to the herbicide paraquat and the insecticide rotenone.

7 Sep 2005

New key evidence supports claims that some types of cancer originate with defects in stem cells

Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg and the Institute of Biomedical Research of the Parc Científic de Barcelona (IRB-PCB) have now added key evidence to claims that some types of cancer originate with defects in stem cells.

4 Sep 2005

Release of the neurotransmitter GABA halts stem cell production in the brain

Release of the neurotransmitter GABA by adult neuronal precursor cells that develop into neurons limits stem cell proliferation, according to a study at Yale School of Medicine in the September issue of Nature Neuroscience.

1 Sep 2005

Molecular switch that turns on the production of myelin

Scientists at New York University School of Medicine report in a new study that they have identified the molecular switch that turns on the production of myelin, the fatty insulation around nerve cells that ensures swift and efficient communication in the nervous system.

1 Sep 2005

Study points to link to neurodegenerative disease target

A University of California - San Francisco (UCSF) study has found that a specific signaling link between neurons and muscles in the fruit fly is essential for keeping the insect's nervous system stable.

1 Sep 2005

Been there, done that!

One of the neural oddities of "declarative" memory--the recall of past things and events--is that some experiments have shown that recognizing a familiar object is accompanied by a reduction in activity of the brain's memory centers in the medial temporal lobe. Such a reduction seems counterintuitive, since remembering seems to be a positive event.

1 Sep 2005

Researchers link individual preferences to neuronal activity in brain

Life is full of choices. But how do individuals know what their preferences are and how do they act on them? And what leads mothers to make choices that benefit or lead to neglect of her offspring? Based on research performed using laboratory rats, a team of neuroscience researchers at Rutgers University-Newark suggest that an intricate system exists within the brain for establishing individual preferences, which ultimately impacts choices.

1 Sep 2005

Tools for studying the chemistry of the brain, neuron by neuron

The human brain is composed of billions of cells, each a separate entity that communicates with others. The chemical interaction of those cells determines personality, controls behavior and encodes memory; but much remains to be understood.

1 Sep 2005

Teenage drug use can lead to adult addiction and heart attack

A new study from the Howard Florey Institute in Melbourne may help explain why people who experimented with amphetamines, such as 'speed', as teenagers are more likely to become addicted and more susceptible to heart attack following re-use of the drug as adults.

30 Aug 2005

Study shows humans have ability to track odors

Though humans may never match the tracking ability of dogs, we apparently have the ability to sniff out and locate odors, according to a new study by scientists from the University of California, Berkeley.

29 Aug 2005

Inhibitory systems essential for controlling the pattern of activity in the cortex

Inhibitory systems are essential for controlling the pattern of activity in the cortex, which has important implications for the mechanisms of cortical operation, according to a Yale School of Medicine study in Neuron.

28 Aug 2005

Ataxin-1 affects the development of the nervous system

In some neurological diseases, too much of what is usually a good thing can be bad, said researchers at Baylor College of Medicine in a report in this week's issue of the journal Cell.

28 Aug 2005

Neurotransmitter orexin influences reward processing - associated with pleasure and reward pathways in the brain

Researchers at the University of Pennsylvania School of Medicine have discovered that the recently identified neurotransmitter orexin (also known as hypocretin) influences reward processing by activating neurons in the lateral hypothalamus region of the brain.

28 Aug 2005

Protein snapin has potential as a drug target in therapies aimed at learning and memory disorders

Rutgers' Bonnie Firestein likens nerve cells to trees -- some are short and bushy with many branches while others are tall with a few branches coming out of one or two main trunks. Different branching patterns correlate with specific disorders and Firestein's quest is to discover how these dissimilar patterns come about and why.

25 Aug 2005

Neuron News and Research

Finding may significantly broaden understanding of how the brain selects and retains information

Microtubules critical to development of mental disorders

Translation elongation factor eEF1A2 is is a potential oncogene that is overexpressed in two-thirds of breast tumors

Clioquinol appears to block the genetic action of Huntington's disease

Sugar-coated markers of brain cell development may help success of stem cell transplants

Researchers discover discrete region of the monkey brain that processes pitch

Animal model of Parkinson's disease reveals striking sensitivity to common environmental toxins

New key evidence supports claims that some types of cancer originate with defects in stem cells

Release of the neurotransmitter GABA halts stem cell production in the brain

Molecular switch that turns on the production of myelin

Study points to link to neurodegenerative disease target

Been there, done that!

Researchers link individual preferences to neuronal activity in brain

Tools for studying the chemistry of the brain, neuron by neuron

Teenage drug use can lead to adult addiction and heart attack

Study shows humans have ability to track odors

Inhibitory systems essential for controlling the pattern of activity in the cortex

Ataxin-1 affects the development of the nervous system

Neurotransmitter orexin influences reward processing - associated with pleasure and reward pathways in the brain

Protein snapin has potential as a drug target in therapies aimed at learning and memory disorders

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