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Definitive multiple sclerosis linkage screen

A cluster of genes on chromosome six is the only one that plays a significant role in multiple sclerosis (MS), according to the most complete genetic study to date in the disorder, presented at the 130th annual meeting of the American Neurological Association in San Diego.

22 Sep 2005

Researchers identify three rapid diagnostic methods that can target antibodies commonly found in multiple sclerosis

Yale School of Medicine researchers have identified three rapid diagnostic methods that can target antibodies commonly found in multiple sclerosis (MS) patients, greatly improving potential diagnosis and treatment.

20 Sep 2005

Oral contraceptives appear to reduce risk of developing multiple sclerosis

Over a three-year period, the risk of developing multiple sclerosis (MS) was reduced in women taking oral contraceptives, according to a study in the September issue of Archives of Neurology.

19 Sep 2005

Cellular mechanism discovery could lead to new treatments for rheumatoid arthritis, multiple sclerosis and Crohn's disease

A major finding by researchers at the La Jolla Institute for Allergy & Immunology (LIAI) has identified a previously unknown cellular mechanism that acts as an off switch for immune system function.

12 Sep 2005

Workshop - stem cells in reproduction and in the brain

"Once we have found the factors by which body cells can be re-programmed into stem cells, then therapeutic cloning might become superfluous," said Hans R. Scholer, director of the Max Planck Institute for Molecular Biomedicine in Munster, Germany, at an international scientific symposium on stem cell research in Kobe, Japan.

10 Sep 2005

Depression improved during telephone therapy in multiple sclerosis patients

Patients with multiple sclerosis showed significant improvement in their depression during 16 weeks of telephone-administered psychotherapy treatment, according to an article in the September issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

5 Sep 2005

Molecular switch that turns on the production of myelin

Scientists at New York University School of Medicine report in a new study that they have identified the molecular switch that turns on the production of myelin, the fatty insulation around nerve cells that ensures swift and efficient communication in the nervous system.

1 Sep 2005

Study points to link to neurodegenerative disease target

A University of California - San Francisco (UCSF) study has found that a specific signaling link between neurons and muscles in the fruit fly is essential for keeping the insect's nervous system stable.

1 Sep 2005

African-American women with mitochondrial DNA variant are at increased risk of breast cancer

African-American women who carry the 10398A mitochondrial DNA allele are 60 percent more likely to develop invasive breast cancer than African-American females without that genetic marker, according to research published in the September 1 issue of "Cancer Research."

1 Sep 2005

Teenage drug use can lead to adult addiction and heart attack

A new study from the Howard Florey Institute in Melbourne may help explain why people who experimented with amphetamines, such as 'speed', as teenagers are more likely to become addicted and more susceptible to heart attack following re-use of the drug as adults.

30 Aug 2005

Birth order not a factor in multiple sclerosis risk

A new Canadian study suggests that the youngest children in a family are not less likely than older siblings to develop multiple sclerosis (MS).

22 Aug 2005

Interferon selectively kills colon cancer cells when combined with irinotecan chemotherapy agent

Johns Hopkins Kimmel Cancer Center scientists have found that interferon, used for 30 years to treat blood cancers, multiple sclerosis and hepatitis, selectively kills colon cancer cells when combined with another standard chemotherapy agent.

16 Aug 2005

Breakthrough in human stem cell research

A breakthrough in human stem cell research, producing embryonic-like cells from umbilical cord blood may substantially speed up the development of treatments for life-threatening illnesses, injuries and disabilities.

16 Aug 2005

Plasma exchange treatment shown most helpful for severe attacks in subtype of MS patients

A Mayo Clinic study demonstrates that only those multiple sclerosis (MS) patients with evidence for antibody deposition or complement activation -- immune cells that can cause tissue destruction -- in their lesions are likely to respond to plasma exchange, a treatment for acute MS attacks.

11 Aug 2005

Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer's disease

Alzheimer disease (AD) is the most common form of senile dementia, with no effective treatment available. In a study appearing online on August 11 in advance of print publication of the September 1 issue of the Journal of Clinical Investigation, Howard Weiner and colleagues from Harvard describe a novel immunologic approach for the treatment of AD.

11 Aug 2005

New study points to new treatments for some forms of Lou Gehrig's disease

A new study indicates that mutant Cu/Zn superoxide dismutase (SOD1) enzymes that are associated with an inherited form of Lou Gehrig's disease cause the protein to become sticky in tissues. Partial unfolding of the mutant protein can expose hydrophobic residues that may promote abnormal interactions with other proteins or membranes in the cell.

11 Aug 2005

Factors inhibiting the brain's natural self-healing process identified

Factors that inhibit the brain's natural self-healing process and that may offer new insights into how to prevent brain damage in premature babies have been identified by a team of researchers supported in part by the March of Dimes.

7 Aug 2005

Potential new target for cannabis-derived drugs as a treatment of inflammatory bowel disease

Researchers investigating anecdotal evidence that cannabis relieves some of the symptoms of inflammatory bowel disease (IBD) have discovered a potential new target for cannabis-derived drugs for treatment of the disease.

2 Aug 2005

Surgical myectomy gives fresh start to patients with hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM), an abnormal thickening of the heart, affects more than 500,000 Americans, making it more common than better-known conditions such as Crohn's disease, Multiple Sclerosis and Anorexia Nervosa.

2 Aug 2005

MediciNova starts phase II clinical trial of MN-166 for multiple sclerosis

MediciNova today announced the enrollment of patients in a Phase II clinical study with MN-166 for the treatment of multiple sclerosis (MS), an inflammatory demyelinating disease of the central nervous system. MN-166 is an orally administered drug with a novel mechanism of action that includes the inhibition of phosphodiesterase IV.

2 Aug 2005

Sclerosis News and Research

Definitive multiple sclerosis linkage screen

Researchers identify three rapid diagnostic methods that can target antibodies commonly found in multiple sclerosis

Oral contraceptives appear to reduce risk of developing multiple sclerosis

Cellular mechanism discovery could lead to new treatments for rheumatoid arthritis, multiple sclerosis and Crohn's disease

Workshop - stem cells in reproduction and in the brain

Depression improved during telephone therapy in multiple sclerosis patients

Molecular switch that turns on the production of myelin

Study points to link to neurodegenerative disease target

African-American women with mitochondrial DNA variant are at increased risk of breast cancer

Teenage drug use can lead to adult addiction and heart attack

Birth order not a factor in multiple sclerosis risk

Interferon selectively kills colon cancer cells when combined with irinotecan chemotherapy agent

Breakthrough in human stem cell research

Plasma exchange treatment shown most helpful for severe attacks in subtype of MS patients

Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer's disease

New study points to new treatments for some forms of Lou Gehrig's disease

Factors inhibiting the brain's natural self-healing process identified

Potential new target for cannabis-derived drugs as a treatment of inflammatory bowel disease

Surgical myectomy gives fresh start to patients with hypertrophic cardiomyopathy

MediciNova starts phase II clinical trial of MN-166 for multiple sclerosis

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