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Lund researchers create nerve cells from human skin

A research breakthrough has proven that it is possible to reprogram mature cells from human skin directly into brain cells, without passing through the stem cell stage. The unexpectedly simple technique involves activating three genes in the skin cells; genes which are already known to be active in the formation of brain cells at the foetal stage.

9 Jun 2011

JDRF, Selecta Biosciences partner to develop type 1 diabetes vaccine

The Juvenile Diabetes Research Foundation (JDRF) and Selecta Biosciences, Inc. announced today that they have established a research collaboration to support Selecta's development of a vaccine technology, which may subsequently help to better treat and potentially prevent type 1 diabetes.

9 Jun 2011

UAB acquires first cell-processing workstation from SANYO

The University of Alabama at Birmingham has taken a significant step toward making sophisticated cell therapy a part of patient care with its acquisition of the first cell-processing workstation (CPWS) from SANYO North America Corporation (SANYO) in the United States.

9 Jun 2011

Agensys, Seattle Genetics to co-develop second antibody-drug conjugate for multiple solid tumors

Seattle Genetics, Inc. and Agensys, Inc., an affiliate of Tokyo-based Astellas Pharma Inc., today announced that Seattle Genetics has exercised an option to co-develop a second antibody-drug conjugate (ADC) under the companies' existing ADC collaboration agreement.

9 Jun 2011

Isotechnika reports consolidated net loss of $2.9 million for first quarter 2011

Isotechnika Pharma Inc. today announced financial and operating results for the three months ended March 31, 2011.

9 Jun 2011

Hepatitis C virus (HCV)-associated liver disease after liver transplantation

Hepatitis C virus (HCV)-associated liver disease continues to be the most common indication for liver transplantation (LT) in the United States accounting for nearly 50% of all liver transplants. Recurrence is universal in patients viremic at the time of transplantation with histological hepatitis developing in the majority of patients. Although the natural history of recurrent HCV is difficult to predict, it is widely accepted that cirrhosis from recurrent HCV occurs in up to 30% of patients within five years of transplantation.

8 Jun 2011

UAB first in U.S. with cell-processing workstation

8 Jun 2011

Topline results from 4SC vidofludimus Phase IIb trial against rheumatoid arthritis

4SC AG, a discovery and development company of targeted small molecule drugs for autoimmune diseases and cancer, today announced topline results from its randomised, double-blind, placebo-controlled Phase IIb clinical trial COMPONENT in RA.

8 Jun 2011

New laboratory method uses SALL4 gene to expand adult hematopoietic stem cells

Researchers in the Department of Pathology at Stony Brook University School of Medicine have discovered a laboratory method to expand adult hematopoietic stem cells (HSCs) using the SALL4 gene. Professor Yupo Ma, M.D., Ph.D., Lead Author, and colleagues used this method to produce a more than 10,000-fold increase in HSCs derived from normal human bone marrow.

7 Jun 2011

Millennium, Seattle Genetics' new brentuximab vedotin trial data presented at ASCO 2011

Seattle Genetics, Inc. and Millennium: The Takeda Oncology Company, a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, today reported updated data from a pivotal trial of brentuximab vedotin in relapsed or refractory Hodgkin lymphoma and a phase II trial in relapsed or refractory systemic anaplastic large cell lymphoma.

7 Jun 2011

Frog skin proteins could treat cancer, diabetes and stroke: New discovery

Scientists at Queen's University Belfast have discovered proteins in frog skins which could be used to treat cancer, diabetes, stroke and transplant patients by regulating the growth of blood vessels.

7 Jun 2011

$Stem cell transplant may help promote bone fracture healing$

Stem cell transplant may help promote bone fracture healing

Researchers at the University of North Carolina at Chapel Hill School of Medicine have shown in an animal study that transplantation of adult stem cells enriched with a bone-regenerating hormone can help mend bone fractures that are not healing properly.

6 Jun 2011

Incyte's ruxolitinib Phase III trial data on myelofibrosis presented at ASCO 2011

Incyte Corporation announced today results from the global, pivotal Phase III clinical program of ruxolitinib in patients with myelofibrosis (MF) at the 2011 American Society of Clinical Oncology (ASCO) Annual Meeting.

6 Jun 2011

ImmunoGen's SAR3419 Phase I trial data on B-cell non-Hodgkin's lymphoma presented at ASCO 2011

ImmunoGen, Inc., a biotechnology company that develops targeted antibody-based anticancer products using its antibody expertise and Targeted Antibody Payload (TAP) technology, today announced the presentation of favorable clinical data for SAR3419 in the treatment of B-cell non-Hodgkin's lymphoma (NHL).

6 Jun 2011

Results from HSPPC-96 Phase 2 study against recurrent gliobastoma presented at ASCO 2011

In data presented at The American Society of Clinical Oncology (ASCO) Annual Meeting, cancer researchers found that the brain tumor vaccine HSPPC-96 for treating recurrent gliobastoma (GBM) has a favorable safety profile and extends survival by two to three times more than the current median survival rate.

4 Jun 2011

Genentech, Astellas announce results of Tarceva Phase III study against advanced NSCLC

Genentech, a member of the Roche Group and Astellas Pharma US, Inc., today announced results of EURTAC, the first Phase III study with Tarceva in Western patients with a genetically distinct type of advanced non-small cell lung cancer (NSCLC).

4 Jun 2011

Study affirms effectiveness of palliative care discussions before LVAD surgery

For patients with severe heart failure, an implanted mechanical pump known as a Left Ventricular Assist Device can be a life-sustaining treatment. Even though the technology involves risks, few patients and their families tend to talk explicitly about the "what ifs" before surgery takes place.

4 Jun 2011

Majority of patients with ulcerative colitis eager to undergo fecal microbiota transplantation

The first study of the social and ethical issues associated with a provocative approach to treatment for ulcerative colitis has found that the majority of potential patients are eager for what is now called "fecal microbiota transplantation" to become available, although many have concerns about donor selection, screening, and methods of delivery.

3 Jun 2011

Media outlets examine case of man cured of HIV, leukemia through bone marrow transplant

In a special report, Reuters examines the case of Timothy Ray Brown, who was cured of HIV and leukemia after undergoing "a bone marrow transplant using cells from a donor with a rare genetic mutation, known as CCR5 delta 32," which researchers knew conveyed resistance to HIV infection.

3 Jun 2011

Study affirms effectiveness of palliative care discussions before LVAD heart surgery

For patients with severe heart failure, an implanted mechanical pump known as a Left Ventricular Assist Device (LVAD) can be a life-sustaining treatment. Even though the technology involves risks, few patients and their families tend to talk explicitly about the "what ifs" before surgery takes place.

2 Jun 2011

Transplant News and Research

Lund researchers create nerve cells from human skin

JDRF, Selecta Biosciences partner to develop type 1 diabetes vaccine

UAB acquires first cell-processing workstation from SANYO

Agensys, Seattle Genetics to co-develop second antibody-drug conjugate for multiple solid tumors

Isotechnika reports consolidated net loss of $2.9 million for first quarter 2011

Hepatitis C virus (HCV)-associated liver disease after liver transplantation

UAB first in U.S. with cell-processing workstation

Topline results from 4SC vidofludimus Phase IIb trial against rheumatoid arthritis

New laboratory method uses SALL4 gene to expand adult hematopoietic stem cells

Millennium, Seattle Genetics' new brentuximab vedotin trial data presented at ASCO 2011

Frog skin proteins could treat cancer, diabetes and stroke: New discovery

Stem cell transplant may help promote bone fracture healing

Incyte's ruxolitinib Phase III trial data on myelofibrosis presented at ASCO 2011

ImmunoGen's SAR3419 Phase I trial data on B-cell non-Hodgkin's lymphoma presented at ASCO 2011

Results from HSPPC-96 Phase 2 study against recurrent gliobastoma presented at ASCO 2011

Genentech, Astellas announce results of Tarceva Phase III study against advanced NSCLC

Study affirms effectiveness of palliative care discussions before LVAD surgery

Majority of patients with ulcerative colitis eager to undergo fecal microbiota transplantation

Media outlets examine case of man cured of HIV, leukemia through bone marrow transplant

Study affirms effectiveness of palliative care discussions before LVAD heart surgery

Industry Focus eBook - Cell biology (5th edition) eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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