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Cryo-EM reveals structural dynamics of RNAP-DNA interactions during transcription initiation

Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form a node known as the transcription bubble, so that one exposed DNA strand can be copied into a complementary RNA strand.

10 Jul 2024

Click-like chemistry enables rapid development of LNPs for enhanced mRNA delivery

Imagine a scenario where a skilled hacker must upload critical software to update a central server and thwart a potentially lethal virus from wreaking havoc across a vast computer network.

10 Jul 2024

Efficient multi-site genome editing with retron-derived multitrons

Genome editing has become a widely adopted technology to modify DNA in cells, allowing scientists to study diseases in the lab and develop therapies that repair disease-causing mutations.

10 Jul 2024

Exploring the benefits of miniaturizing NGS library preparation

In this interview, Huw Rees, a field application scientist at SPT Labtech, discusses the benefits of miniaturization in NGS library preparation and how using mosquito® can give you more value for your money.

From SPT Labtech 10 Jul 2024

Researchers call for ethical guidance on use of AI in healthcare

The ethical implications of deploying Large Language Models (LLMs) in healthcare through a systematic review.

10 Jul 2024

60 years in the making: Nanoparticles revolutionize nucleotide delivery

Researchers trace the 60-year evolution of lipid nanoparticles (LNPs) for nucleic acid delivery, highlighting their potential to revolutionize gene therapy with safer and more effective treatments.

10 Jul 2024

World’s first map of human brain lipids created

Scientists have found that 93% of the lipids in brain tissue are distributed differently in the white and gray matter, the subcortex, the visual and motor cortices, and the prefrontal cortex, which is responsible for decision-making, social behavior, and other functions.

10 Jul 2024

Novel device uses a simple blood test to detect early stage lung cancer

University of Queensland researchers have designed a device that uses a simple blood test to detect early stage lung cancer.

10 Jul 2024

Study finds increased risk of lumbar spinal fusion failure in diabetic patients

A new study from orthopedic researchers at The University of Toledo has found lumbar spinal fusion procedures are far more likely to fail in individuals with diabetes.

9 Jul 2024

Newcells Biotech appoints Emile Shaffu as Director of Sales

Newcells Biotech, a leading drug discovery partner specializing in developing in vitro models and bespoke assay services to improve the prediction of in vivo human outcomes, today announced the appointment of Emile Shaffu as Director of Sales.

From Newcells Biotech 9 Jul 2024

Agreement to explore Optimer vehicles for targeted delivery of siRNA

New collaboration will evaluate Aptamer’s fibrotic liver delivery vehicles with siRNA.

From Aptamer Group 9 Jul 2024

Revolutionary 3D imaging model enhances IVF blastocyst selection

Innovative research, presented today at the ESHRE 40th Annual Meeting in Amsterdam, has introduced a novel 3D imaging model designed to identify features of blastocysts – the early stage of development for an implanted embryo – associated with successful pregnancies.

8 Jul 2024

Study reveals social disparities in achieving live births following ART treatment

Novel research, presented today at the ESHRE 40th Annual Meeting in Amsterdam, reveals significant social disparities in achieving live births following assisted reproductive technology (ART) treatment.

8 Jul 2024

New technology reveals the critical role of sleep in infant brain development

Researchers have developed advanced technology to measure neonatal sleep patterns, revealing how sleep significantly impacts brain development before and after birth.

8 Jul 2024

Majority of people prefer hospital-level care at home

Hospital-level care provided in a patient's own home is appealing to a majority of people for its convenience, comfort and effectiveness, according to a USC Schaeffer Center study.

8 Jul 2024

NIH funds AI chatbot project for personalized depression treatment in Black and African Americans

As a leader in innovative health solutions, George Mason University's College of Public Health received a National Institutes of Health (NIH) AIM-AHEAD program grant to pilot an artificial intelligence (AI) chatbot for Black and African Americans with depression.

8 Jul 2024

Maternal morbidity and pregnancy risks higher for gestational carriers

Gestational carriers, also known as surrogates, experience an elevated risk of severe maternal morbidity and adverse pregnancy outcomes compared to women who conceive naturally or through in vitro fertilization (IVF), according to new research presented today at the ESHRE 40th Annual Meeting in Amsterdam.

8 Jul 2024

Study shows safety of pulsed field ablation for treating patients with atrial fibrillation

Pulsed field ablation (PFA) is safe for treating patients with common types of atrial fibrillation (AF), according to the largest study of its kind on this new technology, led by the Icahn School of Medicine at Mount Sinai.

8 Jul 2024

Case Western Reserve University receives $1.5M grant for oral drug trial to prevent blindness in RP patients

There's only one U.S. Food and Drug Administration-approved therapy for an inherited retinal disease, and dozens of retinitis pigmentosa (RP) genes for which no therapy is available.

8 Jul 2024

New 'band-aid' measures body biomarkers that indicate health or disease through sweat

Scientists from Nanyang Technological University, Singapore (NTU Singapore) have developed a 'band-aid' or plaster that measures body 'biomarkers' that can indicate health or disease through sweat, paving the way for a new non-invasive and effective way for patients to monitor their health.

8 Jul 2024

Technology News and Research

Cryo-EM reveals structural dynamics of RNAP-DNA interactions during transcription initiation

Click-like chemistry enables rapid development of LNPs for enhanced mRNA delivery

Efficient multi-site genome editing with retron-derived multitrons

Exploring the benefits of miniaturizing NGS library preparation

Researchers call for ethical guidance on use of AI in healthcare

60 years in the making: Nanoparticles revolutionize nucleotide delivery

World’s first map of human brain lipids created

Novel device uses a simple blood test to detect early stage lung cancer

Study finds increased risk of lumbar spinal fusion failure in diabetic patients

Newcells Biotech appoints Emile Shaffu as Director of Sales

Agreement to explore Optimer vehicles for targeted delivery of siRNA

Revolutionary 3D imaging model enhances IVF blastocyst selection

Study reveals social disparities in achieving live births following ART treatment

New technology reveals the critical role of sleep in infant brain development

Majority of people prefer hospital-level care at home

NIH funds AI chatbot project for personalized depression treatment in Black and African Americans

Maternal morbidity and pregnancy risks higher for gestational carriers

Study shows safety of pulsed field ablation for treating patients with atrial fibrillation

Case Western Reserve University receives $1.5M grant for oral drug trial to prevent blindness in RP patients

New 'band-aid' measures body biomarkers that indicate health or disease through sweat

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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