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New strategy targets rare B cells for effective HIV vaccine development

Germline-targeting epitope scaffold nanoparticles elicit rare broadly neutralizing antibody (bnAb) precursors against human immunodeficiency virus (HIV).

3 Jun 2024

Scientists identify genetic cause of rare, life-threatening immunodeficiency disorders in children

Scientists have pinpointed genetic changes that can leave children born with little to no immune defence against infection.

3 Jun 2024

Study reveals disparities in the delivery of cancer-related care at minority serving hospitals

It’s important to ensure that care provided at US hospitals that predominantly serve Black and Hispanic populations is as high-quality as the care provided at other US hospitals. New research reveals significant disparities in the delivery of cancer-related care at minority serving hospitals (MSHs) compared with non-MSHs, however.

3 Jun 2024

Foam technology revolutionizes gene therapy, boosting efficiency and safety

Liquid foam gene delivery significantly enhances transfection efficiency and safety, offering a cost-effective alternative to conventional methods.

3 Jun 2024

Omega-3 supplements show promise in battling osteoarthritis

A recent study in Nutrients reviewed the efficacy of omega-3 polyunsaturated fatty acids (PUFAs) in slowing the progression of osteoarthritis (OA) by reducing inflammation and supporting joint health.

2 Jun 2024

Stem cell models unlock secrets of early human embryo development

A new study using stem cell-based models has shed new light on how the human embryo begins to develop, which could one day benefit the development of fertility treatment.

31 May 2024

Super-resolution microscopy offers high-resolution view of virus replication inside cells

A new, nano-scale look at how the SARS-CoV-2 virus replicates in cells may offer greater precision in drug development, a Stanford University team reports in Nature Communications.

31 May 2024

Breakthrough CAR T therapy and shorter targeted therapy durations offer hope for patients with leukemia

The novel anti-CD19 autologous chimeric antigen receptor (CAR) T cell therapy obecabtagene autoleucel (obe-cel) achieved durable remissions in 40% of patients with relapsed or refractory B-ALL without a subsequent stem cell transplant (SCT), according to results from the Phase Ib/II FELIX clinical trial presented today by Elias Jabbour, M.D., professor of Leukemia.

31 May 2024

From ancient remedies to modern medicine: Inorganic materials offer new hope for tissue regeneration

For centuries, civilizations have used naturally occurring, inorganic materials for their perceived healing properties.

31 May 2024

RNA virus hiding in common human parasite may exacerbate toxoplasmosis

An international team led by researchers at the University of Toronto has found a new RNA virus that they believe is hitching a ride with a common human parasite.

31 May 2024

New method enhances the efficacy of bispecific antibody therapies in treating solid tumors

Professor Seung-Woo Lee and PhD candidate Kun-Joo Lee from the Department of Life Sciences at Pohang University of Science and Technology (POSTECH), in collaboration with NeoImmuneTech Director Donghoon Choi and Professors Dae Hee Kim and Sun Shim Choi from Kangwon National University, have revealed a groundbreaking method to significantly enhance the efficacy of bispecific antibody therapies in treating solid tumors.

31 May 2024

TMPRSS2 protein facilitates SARS-CoV-2 entry via unexpected pathway

How exactly do Sars-Cov-2 particles enter host cells? An international team led by Dr Richard Brown from Dr Daniel Todt's Computational Virology group at the Department of Molecular and Medical Virology at Ruhr University Bochum, Germany, together with researchers from the Paul-Ehrlich-Institut, investigated this question.

31 May 2024

New research center delves into ubiquitin's role in cancer

The German Research Foundation (DFG) has now approved a new Collaborative Research Centre in the search for innovative therapies against cancer: Researchers from the Technical University of Munich (TUM), Goethe University Frankfurt and Julius-Maximilians-Universität Würzburg (JMU) have joined forces for this purpose.

31 May 2024

The chicken and egg problem of fighting another flu pandemic

Even a peep of news about a new flu pandemic is enough to set scientists clucking about eggs.

31 May 2024

Single infusion of engineered T-cells achieves lasting asthma remission in mice

Researchers demostrate that durable asthma remission can be achieved with engineered and long-lived CAR T-cell treatment in mice.

31 May 2024

COVID-19 associated with higher risk of erectile dysfunction

Men previously diagnosed with COVID-19 are at a greater risk of developing new-onset erectile dysfunction.

31 May 2024

Researchers uncover two classes of genetic causes for pediatric chordoma

Little is known about the genetics and biology of chordoma, a rare and aggressive bone tumor. Chordomas occur in approximately one in a million people in the U.S. a year and only five percent of these are in children.

30 May 2024

Study may facilitate the development of new personalized treatments for schizophrenia An International Study Publi...

An international study led by the Hospital del Mar Medical Research Institute, in collaboration with researchers from the Neuropsychopharmacology Group at the University of the Basque Country (UPV/EHU) and researchers from the CIBER of Mental Health (CIBERSAM), and published in Nature Communications, may facilitate the creation of new personalized treatments for people diagnosed with schizophrenia.

30 May 2024

Study examines the cost-effectiveness of a targeted immunotherapy for lung cancer

Many countries with national healthcare systems or payers such as insurance companies use cost-effectiveness analyses to decide whether to cover new medicines, balancing treatment costs with potential health benefits.

30 May 2024

Stem cell breakthrough: EPHA2 protein may hold key to safer regenerative therapies

Pluripotent stem cells (PSCs) are a type of stem cells capable of developing into various cell types. Over the past few decades, scientists have been working towards the development of therapies using PSCs.

30 May 2024

B Cell News and Research

New strategy targets rare B cells for effective HIV vaccine development

Scientists identify genetic cause of rare, life-threatening immunodeficiency disorders in children

Study reveals disparities in the delivery of cancer-related care at minority serving hospitals

Foam technology revolutionizes gene therapy, boosting efficiency and safety

Omega-3 supplements show promise in battling osteoarthritis

Stem cell models unlock secrets of early human embryo development

Super-resolution microscopy offers high-resolution view of virus replication inside cells

Breakthrough CAR T therapy and shorter targeted therapy durations offer hope for patients with leukemia

From ancient remedies to modern medicine: Inorganic materials offer new hope for tissue regeneration

RNA virus hiding in common human parasite may exacerbate toxoplasmosis

New method enhances the efficacy of bispecific antibody therapies in treating solid tumors

TMPRSS2 protein facilitates SARS-CoV-2 entry via unexpected pathway

New research center delves into ubiquitin's role in cancer

The chicken and egg problem of fighting another flu pandemic

Single infusion of engineered T-cells achieves lasting asthma remission in mice

COVID-19 associated with higher risk of erectile dysfunction

Researchers uncover two classes of genetic causes for pediatric chordoma

Study may facilitate the development of new personalized treatments for schizophrenia An International Study Publi...

Study examines the cost-effectiveness of a targeted immunotherapy for lung cancer

Stem cell breakthrough: EPHA2 protein may hold key to safer regenerative therapies

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