immunity News and Research

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DAPK3 slows tumor growth by activating fierce-sounding STING pathway

The glow of a panther's eyes in the darkness. The zig-zagging of a shark's dorsal fin above the water. Humans are always scanning the world for threats.

26 Mar 2021

Newly identified pathway controls dangerous overreactions in the body's immune system

Scientists at Sinai Health say they have discovered a new pathway that controls dangerous overreactions in a body's immune system, including deadly forms of hyper-inflammation.

26 Mar 2021

Study: COVID-19 vaccines may remain effective against new influenza viruses

Influenza vaccines need to be evaluated every year to ensure they remain effective against new influenza viruses.

26 Mar 2021

Dual-antigen COVID-19 vaccine elicits humoral and cellular immune responses in mice

The scientific consensus is that safe and highly effective vaccines are required to end the ongoing pandemic of coronavirus disease 2019 COVID-19, caused by SARS-CoV-2. A new study describes a new vaccine that presents two viral antigens to the human immune system, in order to elicit a more efficacious response.

25 Mar 2021

Could an mRNA vaccine second dose reduce cellular immunity in previously infected individuals?

A new study, which was released on the bioRxiv* preprint server, shows the differential effect that a standard vaccine protocol may have on individuals, based on their history of prior infection with the virus.

25 Mar 2021

Researchers examine SARS-CoV-2 RNA interactome

A new study focuses on the identification of RNA-binding protein by mass spectrometry (ChIRP-M/S) approach. This study develops a global map that contains the complete set of host proteins that involve the SARS-CoV-2 genome during infection. This study has successfully identified new SARS-CoV-2 host dependency factors by merging proteomics data with gene silencing experiments. Such a discovery has paved new roads to develop more antiviral therapies.

25 Mar 2021

Researchers conduct online survey on people’s intentions regarding COVID-19 vaccination

Ahead of the first U.S. emergency use authorization for a COVID-19 vaccine, only half of Americans said they were likely to get vaccinated as soon as possible, according to an in-depth study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

25 Mar 2021

COVID vaccines have only 17% detectable antibodies against SARS-CoV-2 virus

When clinical trials were conducted to determine the immunogenicity -- the ability to elicit an immune response -- for the first two vaccines marshaled against SARS-CoV-2the virus that causes COVID-19, one group was not among those included: people who have received solid organ transplants and others (such as those with autoimmune disorders) who are immunocompromised.

25 Mar 2021

Reduced mRNA COVID-19 vaccine response in nursing home residents

A recent study has examined the response of nursing home residents who were naïve to SARS-CoV-2 infection following vaccination by the mRNA BNT162b2 model from Pfizer-BioNTech.

24 Mar 2021

Pangolin coronavirus sheds light on UK SARS-CoV-2 variant's evolutionary trajectory

Researchers at the Division of Infection and Immunity, University College London, UK, have provided key insights into the characteristics of the B.1.1.7 (or UK) variant of SARS-CoV-2.

24 Mar 2021

Neutralizing antibodies to SARS-CoV-2 in mice depend on Fc effector function

A new study reports the essential nature of Fc-mediated functionalities in determining the efficacy of such antibodies.

24 Mar 2021

Delays in TB diagnosis often exceed WHO’s recommendations, shows study

Tuberculosis remains a rare disease in the United States, but when it does occur, delays in diagnosing it often exceed recommendations by the World Health Organization, according to a new report by Harvard Medical School researchers published March 22 in The Lancet Infectious Diseases.

24 Mar 2021

Delaying second doses of COVID-19 vaccines can reduce positive cases

Delaying second doses of COVID-19 vaccines should reduce case numbers in the near term; however, the longer term case burden and the potential for evolution of viral ‘escape’ from immunity will depend on the robustness of immune responses generated by natural infections and one or two vaccine doses, according to a study from McGill University and Princeton University published today in Science.

24 Mar 2021

Study may lead to more refined approaches for head and neck cancers

By targeting an enzyme that plays a key role in head and neck cancer cells, researchers from the UCLA School of Dentistry were able to significantly slow the growth and spread of tumors in mice and enhance the effectiveness of an immunotherapy to which these types of cancers often become resistant.

24 Mar 2021

Study reveals arsenal used by protozoans to make leishmaniasis more severe

Researchers have succeeded in revealing the arsenal used by protozoans of the genus Leishmania in human cells to make leishmaniasis more severe, especially in cases of the mucocutaneous variety of the disease, which can cause deformations in patients.

24 Mar 2021

SARS-CoV-2 infection after vaccination is possible, shows study

In a letter to The New England Journal of Medicine, published online March 23, 2021, a group of investigators from University of California San Diego School of Medicine and the David Geffen School of Medicine at UCLA report COVID-19 infection rates for a cohort of health care workers previously vaccinated for the novel coronavirus.

24 Mar 2021

CureVac's COVID-19 vaccine protects mice against emerging SARS-CoV-2 variants

The CVnCoV mRNA vaccine showed neutralizing antibody levels and completely protected mice infected with the B.1.351 variant. No viral genomes were seen in oral swabs, lungs, or brain.

23 Mar 2021

Research identifies ways to prevent coronavirus spread to the nervous system

A number of studies have shown that human coronaviruses, including SARS-CoV-2 which causes COVID-19, appear to attack neurons and the nervous system in vulnerable populations.

23 Mar 2021

Study shows single dose of mRNA vaccine may suffice for those with prior SARS-CoV-2 infection

A recent study by researchers from Philadelphia, currently available on the medRxiv preprint server, shows that individuals with prior infection caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibit substantial immune memory and develop a robust response to the first dose of an mRNA vaccine.

23 Mar 2021

Computational analysis reveals why new SARS-CoV-2 variants bind better to human cells

All viruses mutate as they make copies of themselves to spread and thrive. SARS-CoV-2, the virus the causes COVID-19, is proving to be no different. There are currently more than 4,000 variants of COVID-19, which has already killed more than 2.7 million people worldwide during the pandemic.

23 Mar 2021

immunity News and Research

DAPK3 slows tumor growth by activating fierce-sounding STING pathway

Newly identified pathway controls dangerous overreactions in the body's immune system

Study: COVID-19 vaccines may remain effective against new influenza viruses

Dual-antigen COVID-19 vaccine elicits humoral and cellular immune responses in mice

Could an mRNA vaccine second dose reduce cellular immunity in previously infected individuals?

Researchers examine SARS-CoV-2 RNA interactome

Researchers conduct online survey on people’s intentions regarding COVID-19 vaccination

COVID vaccines have only 17% detectable antibodies against SARS-CoV-2 virus

Reduced mRNA COVID-19 vaccine response in nursing home residents

Pangolin coronavirus sheds light on UK SARS-CoV-2 variant's evolutionary trajectory

Neutralizing antibodies to SARS-CoV-2 in mice depend on Fc effector function

Delays in TB diagnosis often exceed WHO’s recommendations, shows study

Delaying second doses of COVID-19 vaccines can reduce positive cases

Study may lead to more refined approaches for head and neck cancers

Study reveals arsenal used by protozoans to make leishmaniasis more severe

SARS-CoV-2 infection after vaccination is possible, shows study

CureVac's COVID-19 vaccine protects mice against emerging SARS-CoV-2 variants

Research identifies ways to prevent coronavirus spread to the nervous system

Study shows single dose of mRNA vaccine may suffice for those with prior SARS-CoV-2 infection

Computational analysis reveals why new SARS-CoV-2 variants bind better to human cells

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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