Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Anti-metabolic syndrome efforts needed for young ALL survivors

Children with acute lymphoblastic leukemia are at risk for developing the metabolic syndrome during maintenance therapy, suggest study findings.

5 Mar 2013

Express Scripts finds decline in 2012 U.S. spending on traditional prescription drugs

For the first time in more than 20 years, there was a decrease in 2012 U.S. spending on traditional prescription drugs — primarily pills people take to treat more common diseases such as high cholesterol and high blood pressure — according to new data released today by Express Scripts.

5 Mar 2013

RNA interference identifies function of genes linked with cardiovascular disease

Studies screening the genome of hundreds of thousands of individuals (known as Genome-wide association studies or GWAS) have linked more than 100 regions in the genome to the risk of developing cardiovascular disease.

1 Mar 2013

Pivotal study of olesoxime in Spinal Muscular Atrophy receives positive interim review

Trophos SA, a clinical stage pharmaceutical company developing innovative therapeutics from discovery to clinical validation for under-served medical needs in neurology and cardiology, announced the completion of the interim analysis of the pivotal efficacy study of olesoxime in the rare neurodegenerative condition Spinal Muscular Atrophy (SMA).

1 Mar 2013

LDL apheresis can reduce cholesterol levels in patients with familial hypercholesterolemia

Some patients are genetically prone to such dangerously high levels of cholesterol that no amount of diet, exercise and medications can reduce their cholesterol to safe levels.

1 Mar 2013

Otsuka receives FDA approval for ABILIFY MAINTENA to treat schizophrenia

Otsuka Pharmaceutical Co., Ltd. (Otsuka) and H. Lundbeck A/S (Lundbeck) announced the U.S. Food and Drug Administration (FDA) has approved ABILIFY MAINTENA (aripiprazole) for extended- release injectable suspension, an intramuscular (IM) depot formulation indicated for the treatment of schizophrenia.

1 Mar 2013

Stem cell line could also advance research into liver cancers, cystic fibrosis

Chronic or acute, liver failure can be deadly. Toxins take over, the skin turns yellow and higher brain function slows. "There is no effective therapy at the moment to deal with the toxins that build up in your body," said Neil Talbot, a Research Animal Scientist for the USDA Agricultural Research Service. "Their only option now is to transplant a liver."

1 Mar 2013

Researchers to discuss health issues at Society of Toxicology's Annual Meeting and ToxExpo

Researchers will meet at the Society of Toxicology's Annual Meeting and ToxExpo March 10-16 to discuss a number of health concerns that have received growing public attention over the past several months.

27 Feb 2013

Heart-healthy habits at young age can help prevent future cardiovascular disease

Adults are not the only ones who should focus on good heart health. One University of Alabama at Birmingham (UAB) primary care physician said starting heart-healthy habits at a young age can help build a future free from cardiovascular disease.

27 Feb 2013

Genetic testing strategy for familial high cholesterol questioned

Current testing strategies for the families of patients with familial hypercholesterolemia may not be an efficient use of health resources, suggest study results published in The Lancet.

25 Feb 2013

Familial Hypercholesterolaemia patients often inherit small-effect changes in several genes rather than a large-effect mutation in a single gene

Research published Online First in The Lancet provides new evidence that a substantial proportion of individuals with a clinical diagnosis of Familial Hypercholesterolaemia (FH) inherit a combination of small-effect changes in several genes (polygenic) rather than a large-effect mutation in a single gene (monogenic).

22 Feb 2013

Positive health indicators associated with avocado consumption

New analysis of data from the National Health and Nutrition Examination Survey (NHANES) , a program of the Centers for Disease Control and Prevention (CDC), indicates that consuming avocados may be associated with better diet quality and nutrient intake level, lower intake of added sugars, lower body weight, BMI and waist circumferences, higher "good cholesterol" levels and lower metabolic syndrome risk.

22 Feb 2013

Study finds new mutation in UBIAD1 gene that causes Schnyder corneal dystrophy

Research conducted by Dr. Jayne S. Weiss, Professor and Chair of Ophthalmology at LSU Health Sciences Center New Orleans, and colleagues has discovered a new mutation in a gene that causes Schnyder corneal dystrophy (SCD.)

22 Feb 2013

Positive effect of smoking cessation becomes noticeable within a short period of time: Study

Professor Hermann Brenner and colleagues analyzed the data of 8.807 individuals aged between 50 and 74 years using data of Saarland citizens. "We were able to show that the risk of smokers for cardiovascular diseases is more than twice that of non-smokers. However, former smokers are affected at almost the same low rate as people of the same age who never smoked," says Brenner.

21 Feb 2013

Calcium supplement intake may increase risk of death from heart disease in men

In a new study from the National Institutes of Health, startling results showed that men who took calcium supplements were more apt to die of heart disease than those who didn't get extra calcium in supplement form.

20 Feb 2013

Heart OMics in AGEing project receives European Commission grant

The HOMAGE (Heart OMics in AGEing) project, coordinated by the French National Institute of Health and Medical Research (INSERM), has been awarded a grant by the European Commission for a 6 year period.

20 Feb 2013

Study assesses ischaemic and haemorrhagic risk linked with history of stroke or TIA

Heart and cerebro-vascular disorders represent the two leading causes of death throughout the world. They are sometimes combined in a single patient and their combination represents both a considerable risk to the patient and a therapeutic challenge.

20 Feb 2013

High coronary artery calcium together with slow walking speed multiplies risk of mortality

High coronary artery calcium (CAC) together with slow walking speed multiplies the risk of mortality, reveals a new study published in the International Journal of Cardiology. Coronary artery disease is the leading cause of death worldwide and also a common cause of sudden death - heart attack often being the first sign of the disease.

20 Feb 2013

Coronary computed tomography angiography effectively determines risk of heart attacks

Coronary computed tomography angiography (CCTA) is an effective tool for determining the risk of heart attacks and other adverse cardiac events in patients with suspected coronary artery disease but no treatable risk factors, such as high cholesterol or high blood pressure, according to a new study published online in the journal Radiology.

19 Feb 2013

Cholesterol metabolism regulated by bacteria in the small intestine

Researchers at the Sahlgrenska Academy, University of Gothenburg, Sweden, show that cholesterol metabolism is regulated by bacteria in the small intestine. These findings may be important for the development of new drugs for cardiovascular disease.

19 Feb 2013

Cholesterol News and Research

Further Reading

Anti-metabolic syndrome efforts needed for young ALL survivors

Express Scripts finds decline in 2012 U.S. spending on traditional prescription drugs

RNA interference identifies function of genes linked with cardiovascular disease

Pivotal study of olesoxime in Spinal Muscular Atrophy receives positive interim review

LDL apheresis can reduce cholesterol levels in patients with familial hypercholesterolemia

Otsuka receives FDA approval for ABILIFY MAINTENA to treat schizophrenia

Stem cell line could also advance research into liver cancers, cystic fibrosis

Researchers to discuss health issues at Society of Toxicology's Annual Meeting and ToxExpo

Heart-healthy habits at young age can help prevent future cardiovascular disease

Genetic testing strategy for familial high cholesterol questioned

Familial Hypercholesterolaemia patients often inherit small-effect changes in several genes rather than a large-effect mutation in a single gene

Positive health indicators associated with avocado consumption

Study finds new mutation in UBIAD1 gene that causes Schnyder corneal dystrophy

Positive effect of smoking cessation becomes noticeable within a short period of time: Study

Calcium supplement intake may increase risk of death from heart disease in men

Heart OMics in AGEing project receives European Commission grant

Study assesses ischaemic and haemorrhagic risk linked with history of stroke or TIA

High coronary artery calcium together with slow walking speed multiplies risk of mortality

Coronary computed tomography angiography effectively determines risk of heart attacks

Cholesterol metabolism regulated by bacteria in the small intestine

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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