Protein C News and Research

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Research presents new approach to identify therapeutic targets for human diseases associated with protein phase separation

Recent research demonstrates that protein phase separation (PPS) is widely present in cells and drives a variety of important biological functions.

25 Sep 2023

UMMC transplant team performs second pig heart transplant on patient with end-stage heart disease

After world's first successful transplant in 2022, also performed at the University of Maryland Medical Center (UMMC), this groundbreaking transplant team performed second pig heart transplant on patient deemed ineligible for traditional heart transplant.

25 Sep 2023

Spice herbs for diabetes treatment: A focus on Trachyspermum ammi and Pimpinella anisum

Announcing a new article publication for BIO Integration journal. Diabetes mellitus (DM) arises from a cascade of factors, primarily stemming from defective insulin secretion by the pancreas and emergence of insulin resistance.

25 Sep 2023

Study discovers a new endocytic pathway in budding yeast

Endocytosis is an important cellular process through which cells internalize substances such as water and nutrients.

25 Sep 2023

Scientists decode the marker protein that can be used to ‘‘see’’ neuroinflammation

Inflammation is the sign that our body is defending itself against an aggression. But when this response escalates, for example in the brain, it can lead to serious neurological or psychiatric diseases.

25 Sep 2023

Once-weekly ALTUVIIIO® approved in Japan as a new class of factor VIII therapy for hemophilia A

The Japanese Ministry of Health, Labor, and Welfare (MHLW) has granted marketing authorization for ALTUVIIIO.

From Sanofi 25 Sep 2023

PhenomeX announces the release of SpotLight™ Human Lambda reagent for the Beacon® platform to accelerate cell line development workflows

PhenomeX Inc., a functional cell biology company, is pleased to announce that GSK will present data on the SpotLight™ Human Lambda reagent for the Beacon® platform at the 16th annual Conference on Protein Expression in Animal Cells, which is being held in Sitges, Spain from September 24-28, 2023.

From Bruker Cellular Analysis 25 Sep 2023

The power of nanobodies: How they impact COVID-19 immune response

The structures of 340 antibodies (Abs) and 83 nanobodies.

25 Sep 2023

How are SARS-CoV-2 variants outsmarting our immune system and vaccines?

Researchers use multiomics analysis to understand how SARS-CoV-2 variants, including Alpha, Delta, and Omicron, modulate the host's cellular responses and adapt to evade human immunity. The study highlights the potential for targeted therapies against both adaptive and innate immune responses.

25 Sep 2023

Could CaMKK2 enzyme be the key to treating bipolar disorder?

Researchers explore the role of the CaMKK2 signaling pathway in bipolar disorder, suggesting it as a new treatment target. By targeting this enzyme, scientists aim to develop more effective therapies for bipolar symptoms and metabolic dysfunction.

24 Sep 2023

Could metformin be a game changer for heart health in non-diabetics?

Using Mendelian randomization, researchers found that altering seven metformin targets led to improved blood pressure and BMI in non-diabetic individuals. The study suggests the potential for metformin's role in reducing cardiovascular risks in the general population, although more research is needed.

24 Sep 2023

Plant-based proteins boost muscle mass and cut fat in older adults

Plant-based proteins are just as effective as animal-based options in maintaining muscle mass and strength in older adults, a new meta-analysis finds. The study shows that plant proteins can even aid in reducing fat mass, offering a sustainable and healthful option for combating age-related muscle decline.

24 Sep 2023

Exercise boosts immune defense in Lynch syndrome patients

Aerobic exercise, specifically cycling, shows promise in reducing inflammation and boosting immune responses in the colonic tissue of Lynch syndrome patients, a group at high risk for colorectal cancer. The study suggests that regular exercise may offer a preventive approach for this patient population, though further randomized trials are needed.

24 Sep 2023

Study reveals non-coding genetic variants associated with Alzheimer’s disease functioning in microglia

Scientists studying Alzheimer's disease (AD) have identified thousands of genetic variants in the genome in the development of this progressive neurodegenerative disease.

23 Sep 2023

Certain gut microbes may be linked to skeletal health

There is growing evidence that a relative abundance of certain gut microbes may be related to skeletal health, according to a new study published in Frontiers in Endocrinology.

22 Sep 2023

Researchers identify key regulators involved in genesis of multiple sclerosis lesions

By means of CRISPR screening, LMU researchers have provided the first ever comprehensive molecular characterization of T cell infiltration into the central nervous system of people with MS.

22 Sep 2023

New insights into the molecular mechanism of protein degradation

Within the intricate molecular landscape inside of a cell, the orchestration of proteins demands precise control to avoid disease.

22 Sep 2023

Peptide vaccine targets H3K27M mutation in midline gliomas, shows promise in early trials

Tumor vaccines can help the body fight cancer. These vaccines alert the patient's immune system to proteins that are carrying cancer-typical alterations.

22 Sep 2023

New anticancer treatment technology targets cancer cell lysosomes and overcomes drug resistance

A groundbreaking anticancer treatment technology that selectively targets cancer cell lysosomes and overcomes drug resistance has been developed by Professor Ja-Hyoung Ryu and his research team in the Department of Chemistry at UNIST.

22 Sep 2023

Discovery lead to better methods for reducing mosquito-to-human transmission of deadly viruses

Researchers from the Johns Hopkins Malaria Research Institute at the Johns Hopkins Bloomberg School of Public Health have made an important finding about Aedes aegypti mosquitoes - one that could one day lead to better methods for reducing the mosquito-to-human transmission of dengue, yellow fever, Zika, and other harmful and sometimes deadly viruses.

22 Sep 2023

Protein C News and Research

Research presents new approach to identify therapeutic targets for human diseases associated with protein phase separation

UMMC transplant team performs second pig heart transplant on patient with end-stage heart disease

Spice herbs for diabetes treatment: A focus on Trachyspermum ammi and Pimpinella anisum

Study discovers a new endocytic pathway in budding yeast

Scientists decode the marker protein that can be used to ‘‘see’’ neuroinflammation

Once-weekly ALTUVIIIO® approved in Japan as a new class of factor VIII therapy for hemophilia A

PhenomeX announces the release of SpotLight™ Human Lambda reagent for the Beacon® platform to accelerate cell line development workflows

The power of nanobodies: How they impact COVID-19 immune response

How are SARS-CoV-2 variants outsmarting our immune system and vaccines?

Could CaMKK2 enzyme be the key to treating bipolar disorder?

Could metformin be a game changer for heart health in non-diabetics?

Plant-based proteins boost muscle mass and cut fat in older adults

Exercise boosts immune defense in Lynch syndrome patients

Study reveals non-coding genetic variants associated with Alzheimer’s disease functioning in microglia

Certain gut microbes may be linked to skeletal health

Researchers identify key regulators involved in genesis of multiple sclerosis lesions

New insights into the molecular mechanism of protein degradation

Peptide vaccine targets H3K27M mutation in midline gliomas, shows promise in early trials

New anticancer treatment technology targets cancer cell lysosomes and overcomes drug resistance

Discovery lead to better methods for reducing mosquito-to-human transmission of deadly viruses

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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