Clinical Trial News and Research

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Long-term steroid treatment may not be necessary for kidney transplant patients

Long-term use of a medication used to treat kidney transplant patients may not be necessary in individuals with low-to-moderate risk of organ rejection, according to the results of a study led by a University of Cincinnati transplant researcher.

24 Feb 2021

World's largest resource of genome variation data on malaria parasites released

Genome variation data on more than 7,000 malaria parasites from 28 endemic countries is released today (24 February) in Wellcome Open Research.

24 Feb 2021

Study reveals how cancer cells escape death by lymphocytes

Immunotherapy continues to show exciting promise in more effectively combating several tumor types. Many current strategies focus on ensuring the efficient delivery of active cytotoxic cells directly to tumors.

24 Feb 2021

AMP survey results indicate significant decline in molecular diagnostic testing

The Association for Molecular Pathology (AMP), the premier global, molecular diagnostic professional society, today released the preliminary results of its "Molecular Testing for Cancer during COVID-19" survey of clinical laboratories.

23 Feb 2021

Phase 1 clinical trial shows promising results for monoclonal antibodies against MERS coronavirus

A randomized, placebo-controlled Phase 1 clinical trial of two monoclonal antibodies (mAbs) directed against the coronavirus that causes Middle East respiratory syndrome (MERS) found that they were well tolerated and generally safe when administered simultaneously to healthy adults.

23 Feb 2021

New surgical procedure reduces the rate of recurrent strokes among atherosclerotic patients

A surgical procedure advanced and studied by vascular neurosurgeons at Cedars-Sinai dramatically reduced the rate of recurrent strokes among patients with atherosclerotic disease, a new study shows.

23 Feb 2021

Scientists identify new compound that reverses ALS neuron damage

Northwestern University scientists have identified the first compound that eliminates the ongoing degeneration of upper motor neurons that become diseased and are a key contributor to ALS (amyotrophic lateral sclerosis), a swift and fatal neurodegenerative disease that paralyzes its victims.

23 Feb 2021

Universal strain of bacteria derived from healthy human skin can treat eczema

In a new study out of University of California San Diego School of Medicine, researchers have identified a universal strain of bacteria derived from healthy human skin that can treat the most common type of eczema, also known as atopic dermatitis.

23 Feb 2021

Study finds consistent neuroinflammatory response after intracerebral hemorrhage

Understanding how the immune system responds to acute brain hemorrhage could open doors to identifying treatments for this devastating disease.

22 Feb 2021

Mucosal delivery of IFNs a good strategy for COVID-19 prophylaxis post-exposure

Researchers from the UK and Germany recently reported a comprehensive characterization of the SARS-CoV-2 response of human nasal epithelial cells, revealing a response dominated by IFN-I/IIIs. Also, recombinant IFN-I/III treatment was found to efficiently block the replication of SARS-CoV-2, which suggests that mucosal delivery of IFNs may be a good strategy for prophylaxis post-exposure.

22 Feb 2021

'The Virtual Brain': A new tool for epilepsy surgery planning

Epilepsy is one of the most common neurological disorders, affecting over 50 Million people worldwide. Patients suffer from seizures caused by sudden neuronal activity engaging at times large networks of the brain.

20 Feb 2021

Intranasal COVID-19 vaccine candidate preclinically tested at UAB expected to start clinical trial

The Altimmune Inc. vaccine candidate that was tested preclinically at the University of Alabama at Birmingham last year is expected to start patient enrollment for its Phase 1 clinical trial next week.

20 Feb 2021

Transforming immune killer T-cells into 'super soldiers' to fight against cancer

Creating "super soldiers" of specific white blood cells to boost an anti-tumour response has been shown in a series of elegant experiments by Princess Margaret researchers.

20 Feb 2021

Experts advocate for increased diversity in vaccine clinical trials

A team of scientific experts from across the U.S. and Puerto Rico are advocating for increased diversity in vaccine trials after publishing a new report that highlights a decade's worth of disparities.

20 Feb 2021

Hydrogel injection could help repair damage to the heart muscle after heart attack

Researchers at CÚRAM, the SFI Research Centre for Medical Devices based at NUI Galway, and BIOFORGE Lab, at the University of Valladolid in Spain, have developed an injectable hydrogel that could help repair and prevent further damage to the heart muscle after a heart attack event.

19 Feb 2021

Cologne University professor heads new consortium on EU vaccine research network

The European Union is funding the establishment of the new vaccine research network VACCELERATE with a total of 12 million euros for three years.

18 Feb 2021

Combination therapy produces clinical benefit for early stage non-small cell lung cancer

The first randomized Phase II clinical trial to report on single and combined neoadjuvant immune checkpoint inhibitor therapy in stage I-III non-small cell lung cancer (NSCLC) found combination therapy produced a significant clinical benefit, as assessed by major pathologic response (MPR) rate, as well as enhanced tumor immune cell infiltration and immunological memory.

18 Feb 2021

UC San Diego researchers launch clinical trial to test gene therapy for Alzheimer’s disease

Researchers at University of California San Diego School of Medicine have launched a first-in-human Phase I clinical trial to assess the safety and efficacy of a gene therapy to deliver a key protein into the brains of persons with Alzheimer's disease (AD) or Mild Cognitive Impairment (MCI), a condition that often precedes full-blown dementia.

18 Feb 2021

Early immunosuppressive biomarkers could predict bone regeneration after trauma

An abnormal suppression of the immune system linked to the onset of numerous diseases has been associated with poor functional regeneration of traumatic bone injuries.

18 Feb 2021

Biophysicists show how cancer cells become fluidized and squeeze through tissues

Working with colleagues from Germany and the US, researchers at Leipzig University have achieved a breakthrough in research into how cancer cells spread.

18 Feb 2021

Clinical Trial News and Research

Long-term steroid treatment may not be necessary for kidney transplant patients

World's largest resource of genome variation data on malaria parasites released

Study reveals how cancer cells escape death by lymphocytes

AMP survey results indicate significant decline in molecular diagnostic testing

Phase 1 clinical trial shows promising results for monoclonal antibodies against MERS coronavirus

New surgical procedure reduces the rate of recurrent strokes among atherosclerotic patients

Scientists identify new compound that reverses ALS neuron damage

Universal strain of bacteria derived from healthy human skin can treat eczema

Study finds consistent neuroinflammatory response after intracerebral hemorrhage

Mucosal delivery of IFNs a good strategy for COVID-19 prophylaxis post-exposure

'The Virtual Brain': A new tool for epilepsy surgery planning

Intranasal COVID-19 vaccine candidate preclinically tested at UAB expected to start clinical trial

Transforming immune killer T-cells into 'super soldiers' to fight against cancer

Experts advocate for increased diversity in vaccine clinical trials

Hydrogel injection could help repair damage to the heart muscle after heart attack

Cologne University professor heads new consortium on EU vaccine research network

Combination therapy produces clinical benefit for early stage non-small cell lung cancer

UC San Diego researchers launch clinical trial to test gene therapy for Alzheimer’s disease

Early immunosuppressive biomarkers could predict bone regeneration after trauma

Biophysicists show how cancer cells become fluidized and squeeze through tissues

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