Efficacy News and Research

RSS

SARS-CoV-2 variants BA.4 and BA.5 show substantial immune escape compared with BA.1 and BA.2

In a recent study posted to the bioRxiv* pre-print server, researchers characterized the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant of concern (VOC) Omicron’s new sub-lineages, BA.4, BA.5, and BA.3.

26 May 2022

Staying physically active before COVID-19 infection can help reduce disease severity

A consortium of Luxembourgish research institutions studying the national population have been looking to identify factors that may contribute to variations in severity of COVID-19 and its associated symptoms.

26 May 2022

We need to prepare for Monkeypox - now confirmed in 21 countries

Efforts should be made to curb the spread of this virus in order to prevent another pandemic.

25 May 2022

Review addresses the need for innovative adjuvant approaches and delivery strategies for the advancement of new mucosal vaccines

Researchers reviewed available mucosal vaccines discussing the current challenges and ways to advance the existing approaches.

25 May 2022

The effectiveness of sotrovimab vs. molnupiravir in preventing severe COVID-19 outcomes in non-hospitalized high-risk COVID-19 adult patients

Researchers compared the efficacy of sotrovimab and molnupiravir in preventing severe COVID-19 outcomes among non-hospitalized and high-risk COVID-19 patients across England.

25 May 2022

A study on the safety of BNT162b2 COVID vaccine in children under five

In a recent research paper posted to the medRxiv* preprint server, scientists explored the safety of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) BNT162b2 vaccine in children under five years of age.

25 May 2022

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

In a recent study under review at the Scientific Reports journal and posted to the Research Square* preprint server, researchers evaluated the efficacy of messenger ribonucleic acid (mRNA)-based coronavirus disease 2019 (COVID-19) vaccine BNT162b2 in cancer patients under treatment with immune checkpoint inhibitors (ICIs).

25 May 2022

Efficacy of SARS-CoV-2 vaccines declines as pandemic prevalence increases, study says

A new study by a University of Arkansas information systems researcher and his colleague at the University of Waikato in New Zealand shows that COVID vaccine trials conducted in geographic locations with low infection rates had higher efficacy results, compared to trials in locations with high infection rates.

25 May 2022

Anti-SARS-CoV-2 antibodies from breast milk persist in infants’ digestive tract

The current preliminary investigation study published in the journal Nutrients sought to investigate the longevity of anti-SARS-CoV-2 immunoglobulin (Ig)A and IgG in breast milk during the in vitro-simulated gastrointestinal digestion.

24 May 2022

Engineered water nanostructures as a new technology against SARS-CoV-2

In a recent study published in the MDPI journal Nanomaterials, a research group from the United States (US) has shown the possibility of inactivating surrogates of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on surfaces with the use of specific water nanostructures incorporated with nature-derived antimicrobials.

24 May 2022

Study reports on the first instances of in-hospital, household transmission of monkeypox

A new retrospective study of seven patients diagnosed with monkeypox in the UK between 2018 and 2021, suggests that some antiviral medications might have the potential to shorten symptoms and reduce the amount of time a patient is contagious.

24 May 2022

Insilico Medicine nominates novel preclinical candidate targeting 3CL protease for COVID-19 treatment

Insilico Medicine, a clinical-stage end-to-end artificial intelligence (AI)-driven drug discovery company, today announced its nomination of a novel preclinical candidate (PCC) targeting 3C-like (3CL) protease for the treatment of COVID-19.

24 May 2022

Novel ultrasound-assisted laser technique removes arterial plaque safely and efficiently

Atherosclerosis, a buildup of plaque, can lead to heart disease, artery disease, and chronic kidney disease and is traditionally treated by inserting and inflating a balloon to expand the artery.

24 May 2022

Use of computer-aided technology during colonoscopy increases adenoma detection rate

Colonoscopies performed with computer-aided detection, or artificial intelligence, (AI) saw an increase in the overall rate of detection of adenoma, or cancerous and precancerous polyps, by 27 percent in average-risk patients, according to new data presented today at the Digestive Disease Week Annual Meeting.

24 May 2022

NIH awards first part of $30 million grant to USC team for stroke project

When administered soon after the onset of acute ischemic stroke, current approved treatments for the condition can dramatically improve patient outcomes.

24 May 2022

Hamster contact exposure challenge model assesses protection conferred by SARS-CoV-2 vaccination or prior infection against reinfection

Researchers assessed the neutralization efficacy of a saRNA vaccine targeting SARS-CoV-2 S protein against reinfection among hamsters with prior vaccination or infection.

24 May 2022

Findings from the CoVaccS study on parental intention to vaccinate children against COVID

In the current preprint posted to the medRxiv* server, the researchers looked at UK parental intention to vaccinate their children during a time of selective pediatric vaccination.

24 May 2022

Efficacy study of Paxlovid and Molnupiravir in real-world settings shows positive results

In a recent study posted to the medRxiv* pre-print server, researchers evaluated the effectiveness of oral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antivirals, molnupiravir (Lagevrio) or nirmatrelvir/ritonavir (Paxlovid) in a real-world setting.

24 May 2022

Anti-SARS-CoV-2 antibodies persist in breast milk, even after gastrointestinal digestion

Researchers evaluate the persistence of anti-SARS-CoV-2 IgA and IgG in breast milk before and after in vitro gastrointestinal digestion.

23 May 2022

SARS-CoV-2 mRNA vaccines do not stimulate interferon stimulatory gene expression in Aicardi Goutières Syndrome patients

A new study aimed to evaluate the immunostimulatory potential of mRNA vaccines in AGS patients.

23 May 2022

Efficacy News and Research

SARS-CoV-2 variants BA.4 and BA.5 show substantial immune escape compared with BA.1 and BA.2

Staying physically active before COVID-19 infection can help reduce disease severity

We need to prepare for Monkeypox - now confirmed in 21 countries

Review addresses the need for innovative adjuvant approaches and delivery strategies for the advancement of new mucosal vaccines

The effectiveness of sotrovimab vs. molnupiravir in preventing severe COVID-19 outcomes in non-hospitalized high-risk COVID-19 adult patients

A study on the safety of BNT162b2 COVID vaccine in children under five

Immunogenicity of BNT162b2 COVID-19 vaccine in melanoma patients receiving immunotherapy

Efficacy of SARS-CoV-2 vaccines declines as pandemic prevalence increases, study says

Anti-SARS-CoV-2 antibodies from breast milk persist in infants’ digestive tract

Engineered water nanostructures as a new technology against SARS-CoV-2

Study reports on the first instances of in-hospital, household transmission of monkeypox

Insilico Medicine nominates novel preclinical candidate targeting 3CL protease for COVID-19 treatment

Novel ultrasound-assisted laser technique removes arterial plaque safely and efficiently

Use of computer-aided technology during colonoscopy increases adenoma detection rate

NIH awards first part of $30 million grant to USC team for stroke project

Hamster contact exposure challenge model assesses protection conferred by SARS-CoV-2 vaccination or prior infection against reinfection

Findings from the CoVaccS study on parental intention to vaccinate children against COVID

Efficacy study of Paxlovid and Molnupiravir in real-world settings shows positive results

Anti-SARS-CoV-2 antibodies persist in breast milk, even after gastrointestinal digestion

SARS-CoV-2 mRNA vaccines do not stimulate interferon stimulatory gene expression in Aicardi Goutières Syndrome patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News