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Study links high sugar intake to lower childhood asthma risk, while fat, magnesium, and vitamin D increase it

Using Mendelian Randomization, researchers found that high sugar intake may lower childhood asthma risk, while high fat, magnesium, and vitamin D intake increase it.

27 May 2024

New antibody therapy shows promise in combating kidney transplant rejection

Antibody-mediated rejection (AMR) is one of the most common causes of kidney transplant failure. To date, however, no treatment has proven effective in combating this complication in the long term.

27 May 2024

Personalized phage therapy successfully treats antibiotic-resistant infections in animals

A new study demonstrates an advance in treating antibiotic-resistant infections in animals through personalized phage therapy.

27 May 2024

$Osaka University to pioneer world-first clinical trial for refractory prostate cancer with alpha-ray therapy$

Osaka University to pioneer world-first clinical trial for refractory prostate cancer with alpha-ray therapy

A research team at Osaka University will start an investigator-initiated clinical trial for refractory prostate cancer patients after the successful development of a new alpha-ray therapeutic agent ([At-211] PSMA-5) and confirmation of its efficacy in animal models.

27 May 2024

Mediterranean diet cuts environmental impact and improves metabolic health, study finds

Researchers found that a Mediterranean diet with reduced energy intake significantly reduced environmental impacts, such as acidification, eutrophication, and land use, in individuals with metabolic syndrome. Caloric reduction and diet adherence were key factors mediating these benefits.

27 May 2024

Running therapy matches antidepressants for mental health, surpasses for physical benefits

Researchers found that while both antidepressants and group running therapy effectively improved mental health in patients with anxiety and depression, running therapy had significantly better outcomes for physical health indicators.

26 May 2024

SELECT trial shows semaglutide reduces kidney decline in obese patients

The SELECT Trial has revealed the potential of semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, in combating kidney function decline among individuals with overweight or obesity and established cardiovascular disease but without diabetes.

25 May 2024

AI-based body composition analysis predicts lung cancer treatment outcomes

Tafadzwa Chaunzwa, MD, a researcher in the Artificial Intelligence in Medicine (AIM) Program at Mass General Brigham and a senior resident physician at the Harvard Radiation Oncology Program, is the lead author of a paper published in JAMA Oncology.

24 May 2024

Evolving treatment paradigms in multiple myeloma could improve patient outcomes

The treatment landscape for multiple myeloma, the second most common blood cancer, is shifting rapidly, with newly diagnosed patients increasingly being treated with a four-part drug combination that includes a new immunotherapy agent.

24 May 2024

Evaluating systemic thrombolysis for acute portal vein thrombosis in cirrhotic patients

The prevalence of Portal Vein Thrombosis (PVT) varies significantly at different stages of liver disease: 10% in compensated patients, 17% in decompensated patients, 9% in those with acute decompensated cirrhosis, and 2-26% in post-liver transplant patients.

24 May 2024

Two new studies offer insights into the molecular biology of neuropsychiatric disease

Working under the umbrella of the PsychENCODE Consortium, the mental health research project established in 2015 by the National Institutes of Health, a team of Mount Sinai scientists has uncovered important new insights into the molecular biology of neuropsychiatric disease through two new studies published in a special issue of Science on Friday, May 24.

24 May 2024

Immunotherapy-chemotherapy combo boosts survival for patients with metastatic colorectal cancer

A study led by UCLA Health Jonsson Comprehensive Cancer Center researchers found that using a combination of experimental immunotherapy drugs with chemotherapy significantly improves progression-free survival and overall survival for patients with metastatic colorectal cancer who have previously undergone standard chemotherapy treatment when compared to those who received the targeted therapy regorafenib alone.

24 May 2024

Phase 1 trial for EBC-129 progresses into dose expansion

The Experimental Drug Development Centre (EDDC), Singapore's national platform for drug discovery and development, is pleased to announce that the Phase 1 trial for EBC-129 has progressed into dose expansion.

24 May 2024

New immunogenic strain of vaccinia virus unveils potent cancer therapy potential

Vaccinia viruses are therapeutic tools with different biomedical applications depending on the susceptibility characteristics.

24 May 2024

Psilocybin use initiates hyperconnectivity in the brain linked to ego-modifying effects

A new study shows that the use of psilocybin, a compound found in the widely known "magic mushrooms," initiates a pattern of hyperconnectivity in the brain linked to the ego-modifying effects and feelings of oceanic boundlessness.

23 May 2024

In-vivo imaging to quantify collagen morphology in preclinical melanoma models during immunotherapy

Collagen, a major component of the extracellular matrix, plays a crucial role in tumor development.

23 May 2024

Novel catalog of gene-isoform variation unveiled in the developing human brain

A team led by researchers at UCLA and the University of Pennsylvania has produced a first-of-its kind catalog of gene-isoform variation in the developing human brain.

23 May 2024

Study demonstrates causal link between microbial factors and dysfunction of ISCs in colitis

In a study published in Cell Host & Microbe, a research team led by Prof. PAN Wen from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences, in collaboration with research teams led by Prof. ZHU Shu and Prof. SONG Xinyang, demonstrated the causal link between microbial factors and dysfunction of intestinal stem cells (ISCs) in colitis.

23 May 2024

New genetic discoveries offer hope for targeted lupus therapies

Lupus is a lifelong, often painful and occasionally lethal autoimmune disease. Few treatments exist today beyond powerful steroids to knock down a patient's immune system - a therapy that has its own serious risks.

23 May 2024

e-QuoL project: Digital tools for young cancer survivors' follow-up care

The "e-QuoL" project will develop a variety of digital tools to assist young cancer survivors manage their health and their follow-up care.

23 May 2024

Therapy News and Research

Study links high sugar intake to lower childhood asthma risk, while fat, magnesium, and vitamin D increase it

New antibody therapy shows promise in combating kidney transplant rejection

Personalized phage therapy successfully treats antibiotic-resistant infections in animals

Osaka University to pioneer world-first clinical trial for refractory prostate cancer with alpha-ray therapy

Mediterranean diet cuts environmental impact and improves metabolic health, study finds

Running therapy matches antidepressants for mental health, surpasses for physical benefits

SELECT trial shows semaglutide reduces kidney decline in obese patients

AI-based body composition analysis predicts lung cancer treatment outcomes

Evolving treatment paradigms in multiple myeloma could improve patient outcomes

Evaluating systemic thrombolysis for acute portal vein thrombosis in cirrhotic patients

Two new studies offer insights into the molecular biology of neuropsychiatric disease

Immunotherapy-chemotherapy combo boosts survival for patients with metastatic colorectal cancer

Phase 1 trial for EBC-129 progresses into dose expansion

New immunogenic strain of vaccinia virus unveils potent cancer therapy potential

Psilocybin use initiates hyperconnectivity in the brain linked to ego-modifying effects

In-vivo imaging to quantify collagen morphology in preclinical melanoma models during immunotherapy

Novel catalog of gene-isoform variation unveiled in the developing human brain

Study demonstrates causal link between microbial factors and dysfunction of ISCs in colitis

New genetic discoveries offer hope for targeted lupus therapies

e-QuoL project: Digital tools for young cancer survivors' follow-up care

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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