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Pembrolizumab enhances breast cancer treatment regardless of age or menopausal status

New data from the KEYNOTE-756 phase 3 clinical trial show that adding the immunotherapy drug, pembrolizumab, to chemotherapy before and after surgery for breast cancer leads to better outcomes for patients regardless of their age or menopausal status.

20 Mar 2024

Cryoablation could be a new treatment path for breast cancer patients with large tumors

A minimally invasive technique that uses ice to freeze and destroy small, cancerous tumors has now been proven effective for breast cancer patients with large tumors, providing a new treatment path for those who are not candidates for surgery, according to new research to be presented at the Society of Interventional Radiology Annual Scientific Meeting in Salt Lake City.

20 Mar 2024

Study highlights causal associations between gut microbes and hypothyroidism

The association between the microbial community of the gut and hypothyroidism.

20 Mar 2024

Metformin boosts appetite-suppressing metabolite, new study finds

Metformin treatment boosts levels of Lac-Phe, an appetite-suppressing metabolite, potentially offering new insights into its mechanism and opening doors for obesity treatments.

19 Mar 2024

Tracking circulating tumor DNA could indicate gastroesophageal cancer treatment response

Monitoring levels of DNA shed by tumors and circulating in the bloodstream could help doctors accurately assess how gastroesophageal cancers are responding to treatment, and potentially predict future prognosis, suggests a new study led by researchers at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

19 Mar 2024

MRI and lumbar puncture may not be necessary for managing CAR T-cell associated toxicities

Magnetic resonance imaging (MRI) and lumbar puncture (LP) may not always be necessary for diagnosing and managing a serious neurological complication associated with CAR T-cell therapy, according to a new Blood Advances study.

19 Mar 2024

Developing mRNA lipid nanoparticles for treating oral squamous cell carcinoma

A study aiming to develop a Lipid nanoparticles (LNP) platform for treating oral squamous cell carcinoma (OSCC) utilizing p53 mRNA was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of the American Association for Dental, Oral, and Craniofacial Research and the 48th Annual Meeting of the Canadian Association for Dental Research, on March 13-16, 2024, in New Orleans, LA, USA.

19 Mar 2024

Osteoporosis model rats show improved healing with FGF-2 treatment

A study investigating the effects of local application of fibroblast growth factor (FGF-2) on periodontal healing in osteoporosis model rats was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of the American Association for Dental, Oral, and Craniofacial Research and the 48th Annual Meeting of the Canadian Association for Dental Research, on March 13-16, 2024, in New Orleans, LA, USA.

19 Mar 2024

Study reveals new strategy to improve and accelerate recovery from muscle injuries

Muscle injuries are common in the active population, and they cause the majority of player leaves in the world of sport.

19 Mar 2024

NUS study reveals key mechanisms behind drug resistance in relapsed acute myeloid leukemia

Scientists from the National University of Singapore (NUS) have discovered that the evasion of apoptosis is a key driver of drug resistance in patients with relapsed acute myeloid leukaemia (AML), a type of aggressive blood cancer.

19 Mar 2024

Review suggests the middle-aged brain could provide a window into future cognitive health

The middle-aged brain could provide a window into future cognitive health, researchers write in a review publishing March 19 in the journal Trends in Neurosciences.

19 Mar 2024

New drug candidates show promise to reverse HIV immune evasion

University of Pittsburgh School of Medicine scientists have identified drug candidates that show promise to reverse the ability of HIV to escape detection by the immune system.

19 Mar 2024

Discovery could revolutionize stem cell-based brain repair therapy for Parkinson's disease

Neuroscientists at University of Galway have made an exciting discovery that could revolutionize stem cell-based brain repair therapy for Parkinson's disease.

19 Mar 2024

Amid mental health staffing crunch, Medi-Cal patients help one another

Three people gathered in a classroom on a recent rainy afternoon listened intently as Derrick Cordero urged them to turn their negative feelings around.

19 Mar 2024

A blueprint for personality change: Key mechanisms and stability forces

Review explores the four main components—preconditions, triggers, reinforcers, and integrators—that facilitate personality change, alongside forces that maintain stability and prevent significant alterations in personality.

19 Mar 2024

Study uncovers how APOBEC enzymes drive cancer mutations

A research team led by the University of California, Irvine has discovered the key role that the APOBEC3A and APOBEC3B enzymes play in driving cancer mutations by modifying the DNA in tumor genomes, offering potential new targets for intervention strategies.

18 Mar 2024

Therapy News and Research

Pembrolizumab enhances breast cancer treatment regardless of age or menopausal status

Cryoablation could be a new treatment path for breast cancer patients with large tumors

Study highlights causal associations between gut microbes and hypothyroidism

Metformin boosts appetite-suppressing metabolite, new study finds

Tracking circulating tumor DNA could indicate gastroesophageal cancer treatment response

MRI and lumbar puncture may not be necessary for managing CAR T-cell associated toxicities

Developing mRNA lipid nanoparticles for treating oral squamous cell carcinoma

Osteoporosis model rats show improved healing with FGF-2 treatment

Study reveals new strategy to improve and accelerate recovery from muscle injuries

NUS study reveals key mechanisms behind drug resistance in relapsed acute myeloid leukemia

Review suggests the middle-aged brain could provide a window into future cognitive health

New drug candidates show promise to reverse HIV immune evasion

Discovery could revolutionize stem cell-based brain repair therapy for Parkinson's disease

Amid mental health staffing crunch, Medi-Cal patients help one another

A blueprint for personality change: Key mechanisms and stability forces

Study uncovers how APOBEC enzymes drive cancer mutations

Kallistatin expression increases after weight loss, study reveals

Low-level laser therapy offers immediate pain relief for Burning Mouth Syndrome patients

Implantable temperature sensor detects inflammatory flareups in patients with Crohn's disease

Unlocking quinoa's power: Beyond nutrition to drug development

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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