Acetaminophen News and Research

RSS

The pain-reliever acetaminophen (also known as paracetomol) is one of the best-selling over-the-counter medications, used by more than 200 million Americans a year. It is sold under many brand names, including Tylenol, and is an ingredient in nearly 200 medications, both over-the-counter (such as Excedrin, Midol, NyQuil, and Sudafed) and prescription (such as Vicodin).

Over-the-counter pain medications may shorten concussion recovery time

People who take over-the-counter pain relievers after a concussion may recover faster than those who do not take pain relievers, according to a preliminary study released today, March 5, 2025, that will be presented at the American Academy of Neurology's 77th Annual Meeting taking place April 5–9, 2025, in San Diego and online.

5 Mar 2025

Social media and peer pressure fueling dangerous drug misuse

Social media trends and peer pressure can be a dangerous combination to your children and their friends, especially when involving misusing medicines.

22 Feb 2025

Exploring EGCG's role in protecting against acetaminophen-induced liver injury

Announcing a new publication for Acta Materia Medica journal. Excessive consumption of acetaminophen (APAP) has emerged as the primary culprit behind drug-induced liver injury (DILI), with N-acetylcysteine serving as the principal antidote.

21 Feb 2025

Study links fetal acetaminophen exposure to increased risk of ADHD

Fetal acetaminophen exposure increases the likelihood that a child will develop attention-deficit/hyperactivity disorder (ADHD), according to a study published Feb. 6 in Nature Mental Health.

21 Feb 2025

The science of silk fibroin and chitosan: Techniques for biomaterials analysis

An interview on how advanced techniques can be used to enhance silk fibroin and chitosan for drug delivery applications.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 21 Jan 2025

Non-opioid pain relief proven more effective after wisdom teeth removal

A combination of acetaminophen (Tylenol) and ibuprofen (Advil, Motrin) controls pain after wisdom tooth removal better than opioids, according to a Rutgers Health study that could change how dentists treat post-surgical pain.

6 Jan 2025

Breastfeeding after COVID-19 vaccination is safe, with minimal changes to milk composition

This study reveals how SARS-CoV-2 infection significantly alters human milk composition, while COVID-19 vaccination causes minimal, transient changes, underscoring the safety of breastfeeding during vaccination.

19 Dec 2024

Unraveling the mystery of drug-induced liver injury

DILI is broadly categorized into intrinsic and idiosyncratic types. Intrinsic hepatotoxins, such as APAP, cause dose-dependent injury, while idiosyncratic DILI involves complex immune and metabolic interactions that remain poorly understood.

13 Dec 2024

Repeated paracetamol use linked to health risks in older adults

New research, led by experts at the University of Nottingham, has found that repeated doses of paracetamol in people aged 65 and over, can lead to an increased risk of gastrointestinal, cardiovascular and renal complications.

12 Dec 2024

New insights into anti-seizure medications during pregnancy

Two common antiseizure medications, lamotrigine and levetiracetam, are safe to use during pregnancy, according to a Stanford Medicine-led study.

3 Dec 2024

HMGB1 as a key mediator in liver disease pathogenesis

Liver diseases, both acute and chronic, continue to pose significant clinical challenges due to high morbidity and mortality rates.

8 Nov 2024

Weill Cornell Medicine professor receives major grant for pediatric pain management study

Dr. Chani Traube, the Gerald M. Loughlin, MD Professor of Pediatrics at Weill Cornell Medicine, has been awarded a $3.4 million grant, with the possibility of extending to a total of $17 million over five years, from the National Institutes of Health, for a large-scale clinical trial called Optimizing Pain Treatment in Children on Mechanical ventilation (OPTICOM).

1 Nov 2024

Study suggests NSAIDs may lower postoperative delirium risk

Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, may help reduce patients' risk of postoperative delirium, according to a study presented at the ANESTHESIOLOGY® 2024 annual meeting.

20 Oct 2024

Innovative approach to measure acetaminophen in human urine

In recent years, the excessive use of acetaminophen (APAP) has become a significant human hazard and social burden.

16 Oct 2024

AAP publishes first clinical guideline for opioid use in pediatric care

The American Academy of Pediatrics has published its first clinical guideline for pediatricians on prescribing opioids, including explicit instructions on how and when to prescribe these medications for pain while reducing the long-term risk of addiction.

30 Sep 2024

Deciphering miRNA-mediated regulation of liver regeneration: New insights

The liver, a vital organ involved in numerous essential physiological processes such as bile production, plasma protein synthesis, nutrient absorption, detoxification, vitamin storage, macronutrient metabolism, and immune support, has a remarkable regenerative capacity.

29 Jul 2024

Atogepant may decrease the risk of developing rebound headache in people with migraine

A drug used to prevent migraine may also be effective in people with migraine who experience rebound headaches, according to a new study published in the June 26, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

26 Jun 2024

Innovative CAR T cell therapy shows promise for relapsed CIDP patients

This study is led by Professor Junnian Zheng and Ming Shi from the Cancer Institute of Xuzhou Medical University, together with the team of Professor Guiyun Cui and Wei Zhang from the Affiliated Hospital of Xuzhou Medical University.

20 Jun 2024

Acetaminophen shows potential in preventing acute respiratory distress syndrome, organ injury in sepsis patients

A National Institutes of Health (NIH)-supported clinical trial has found that intravenous acetaminophen reduced sepsis patients' risk of having organ injury or developing acute respiratory distress syndrome, a serious condition that allows fluid to leak into the lungs.

20 May 2024