Antiretroviral News and Research

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Digital patient records improve survival in HIV treatment clinics

With 9.5% of its population estimated to be HIV-positive in 2019, Malawi has one of the highest rates of HIV prevalence in the world.

22 Dec 2025

Rapid HIV viral load testing shows mixed effects on seeking care

According to the U.S. Centers for Disease Control and Prevention (CDC) and other sources, there are approximately 1.2 million people living with HIV in the United States, and another 1.2 to 2.2 million who are at highest risk for infection and could benefit from the preventive measure known as HIV pre-exposure prophylaxis (PrEP).

18 Dec 2025

Chemotherapy may reduce HIV-infected T cells

Advancements in HIV/AIDS research, drug development and clinical practice since the 1980s have made it possible for people living with HIV to lead long, productive lives and keep the virus in check at undetectable levels and nontransmissible as long as therapy is maintained.

15 Dec 2025

Long-acting HIV treatment could improve outcomes for breastfeeding women

Sujata Tewari, BA, previously of the Medical Practice Evaluation Center (MPEC) at Massachusetts General Hospital, and Andrea L. Ciaranello, MD, MPH, of the MPEC and Department of Medicine at Massachusetts General Hospital, are the lead and senior authors of a paper published in the Journal of Infectious Diseases, “Long-acting antiretroviral therapy for breastfeeding women with HIV experiencing barriers to adherence in Zimbabwe: Modeling clinical impact and cost-effectiveness.

4 Dec 2025

New rapid test distinguishes real HIV infections from vaccine-related false positives

Since the human immunodeficiency virus (HIV) was identified in 1983, roughly 91.4 million people around the world have contracted the virus and an additional 44.1 million have died from related causes.

3 Dec 2025

Common water pill may be a useful add‑on to the standard HIV treatment

An FDA‑approved medication called spironolactone, often prescribed as a diuretic, or water pill, for heart and blood pressure conditions, may be a useful add‑on to the standard HIV treatment, according to new research from the Valente lab at The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology.

2 Dec 2025

Killer T cell traits explain why some people achieve long-term HIV remission after treatment

Researchers led by a team from Mass General Brigham and the Ragon Institute have discovered why some people living with HIV who are given a treatment called broadly neutralizing anti-HIV antibodies (bNAbs) can safely stop taking standard, lifelong HIV medications and maintain control of the virus for years, while others given the same treatment do not achieve this remission.

1 Dec 2025

Combination immunotherapy may be the key to control HIV without long-term antiviral treatment

A new study from UC San Francisco shows it may be possible to control HIV without long-term antiviral treatment - an advance that points the way toward a possible cure for a disease that affects 40 million people around the world.

1 Dec 2025

Updated Canadian guideline aims to raise awareness of new HIV prevention strategies

Multiple pre-exposure (PrEP) and postexposure (PEP) treatments are now available to prevent HIV infection. An updated Canadian guideline published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.250511 contains 31 recommendations and 10 good practice statements to help clinicians and other health care professionals offer these safe and effective options to teen and adult patients.

1 Dec 2025

Late HIV diagnoses threaten Europe’s progress toward ending AIDS by 2030

Europe is failing to test and treat HIV early, with over half (54%) of all diagnoses in 2024 being made too late for optimal treatment.

27 Nov 2025

Study uncovers how a specific immune cell may contribute to HIV persistence

Researchers from the Institute of Human Virology (IHV) at the University of Maryland School of Medicine have discovered how a specific type of immune cell may contribute to the persistence of HIV infections.

24 Nov 2025

Low-dose THC mitigates harmful side effects and inflammation caused by HIV treatment

Long-term, low doses of THC mitigate many harmful side effects and inflammation caused by HIV and antiretroviral therapy (ART), according to new research from Texas Biomedical Research Institute.

6 Nov 2025

Newly discovered perineural pathway enables HIV virus to redistribute throughout the body

Addressing the question of whether and how immune cells (macrophages) in the central nervous system (CNS) traffic out, researchers have now identified a perineural pathway through which the HIV virus can redistribute throughout the body.

28 Oct 2025

Tryptophan deficiency in breast milk may explain health challenges in children born to mothers with HIV

A new UCLA study reveals that breast milk from women living with HIV contains significantly lower levels of tryptophan, an essential amino acid likely important for infant immune function, growth, and brain development.

28 Oct 2025

New study shows why HIV health recovery fails despite antiretroviral therapy

What if the presence of a well-known but misunderstood viral protein explains why some people living with HIV (PLWH) never recover their health, even with antiretroviral treatment?

3 Oct 2025

HIV protein Tat found to increase vulnerability to tuberculosis

According to the World Health Organization, tuberculosis accounts for one in three deaths among people living with HIV.

18 Sep 2025

Researchers uncover how HIV-1 uses RNA:DNA hybrids to integrate into the genome

Researchers at the German Center for Infection Research (DZIF) at Heidelberg University Hospital have decoded a previously unknown mechanism by which HIV-1 selects its integration targets in the human genome.

16 Sep 2025

New oral antiretroviral shows potential as long-acting HIV pre-exposure prophylaxis

A new HIV antiretroviral shows promise as a long-acting, oral prophylactic agent, according to a new study by Izzat Raheem, Tracy Diamond and colleagues from Merck & Co., Inc., Rahway, NJ, USA, published August 26th in the open-access journal PLOS Biology.

26 Aug 2025

Weill Cornell Medicine leads $14.9 million effort to develop personalized HIV cures

A multi-institutional team led by Weill Cornell Medicine has received a five-year, $14.9 million grant from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, to find ways to remove latent HIV from the cells of individuals with HIV.

17 Aug 2025

How early immune challenges influence oral and systemic health in children

Once viewed only as infectious invaders, bacteria are now understood to play an important role in overall health.

8 Aug 2025

Antiretroviral News and Research

Digital patient records improve survival in HIV treatment clinics

Rapid HIV viral load testing shows mixed effects on seeking care

Chemotherapy may reduce HIV-infected T cells

Long-acting HIV treatment could improve outcomes for breastfeeding women

New rapid test distinguishes real HIV infections from vaccine-related false positives

Common water pill may be a useful add‑on to the standard HIV treatment

Killer T cell traits explain why some people achieve long-term HIV remission after treatment

Combination immunotherapy may be the key to control HIV without long-term antiviral treatment

Updated Canadian guideline aims to raise awareness of new HIV prevention strategies

Late HIV diagnoses threaten Europe’s progress toward ending AIDS by 2030

Study uncovers how a specific immune cell may contribute to HIV persistence

Low-dose THC mitigates harmful side effects and inflammation caused by HIV treatment

Newly discovered perineural pathway enables HIV virus to redistribute throughout the body

Tryptophan deficiency in breast milk may explain health challenges in children born to mothers with HIV

New study shows why HIV health recovery fails despite antiretroviral therapy

HIV protein Tat found to increase vulnerability to tuberculosis

Researchers uncover how HIV-1 uses RNA:DNA hybrids to integrate into the genome

New oral antiretroviral shows potential as long-acting HIV pre-exposure prophylaxis

Weill Cornell Medicine leads $14.9 million effort to develop personalized HIV cures

How early immune challenges influence oral and systemic health in children

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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