Aspergillus News and Research

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Fungicide resistance: A global threat to human, animal, and plant health

Fungi can cause disease in both humans, animals, and plants. Every year, 1.5 million people die from fungal infections, and fungal attacks in food crops threaten food production.

9 Feb 2024

Natural PLA2 inhibitor from marine fungus combats fatty liver disease by silencing lipotoxic pathways

This new article publication from Acta Pharmaceutica Sinica B, discusses the identification of a natural PLA2 inhibitor from the marine fungus Aspergillus sp. c1 for MAFLD treatment that suppressed lipotoxicity by inhibiting the IRE-1α/XBP-1s axis and JNK signaling.

16 Jan 2024

Scientists discover kidney-friendly antifungal that evades resistance

In this investigation, researchers produced powerful antifungals of the polyene class without nephrotoxicity.

9 Nov 2023

Fighting invisible foes: How cryptic fungal pathogens threaten human health and food security

The research paper in PLOS Pathogens delves into the challenges of diagnosing and treating cryptic fungal pathogens, which are difficult to distinguish from common fungi but equally dangerous. The study calls for more accurate diagnostic methods and a better understanding of how these fungi interact with the human immune system and microbiome for effective treatment and prevention.

25 Oct 2023

NIAID grant supports research aimed at improving outcomes for patients with Aspergillus infections

Aspergillus fumigatus is the major airborne fungus present indoors and outdoors that causes various diseases, the severity of which are dependent on an individual's immune status.

17 Oct 2023

Turning fish waste into cancer fighters: How abalone viscera peptides could be the next big thing in medicine

Researchers explore the potential of bioactive peptides from abalone fish viscera for their antimicrobial and anticancer properties. The study finds promising activity against various bacterial and fungal strains, as well as cytotoxic effects on prostate cancer cells.

17 Sep 2023

Mycotoxin contamination is still a serious food/feed safety issue

The updated and most recent evidence of the occurrence and co-occurrence of mycotoxins.

4 Sep 2023

New way to attack fungal infections discovered

Researchers at the RIKEN Center for Sustainable Research Science (CSRS) and the University of Toronto have discovered a new way to attack fungal infections.

31 Jul 2023

Understanding the mechanisms behind rising antifungal drug resistance

In a recent study, researchers addressed the issue of the rise of antifungal drugs-resistant infections and the advent of multidrug-resistant fungal pathogens.

19 Jul 2023

New drug shows synergistic effect with antifungals in killing drug-resistant fungi

A study conducted at the University of São Paulo (USP) in Brazil shows that brilacidin, a new drug tested for treatment of diseases ranging from bacterial skin infections to COVID-19, can kill drug-resistant strains of fungi when combined with two classes of antifungals available on the market.

10 Jul 2023

Endophytic fungi Penicillium verhagenii: an exploration of its anticancer, antioxidant, antimicrobial, and larvicidal activity

Researchers explored the use of endophytic fungi to fabricate selenium nanoparticles.

6 Jun 2023

Unlocking gut health: How indoor environment impacts the microbiota balance

Research paper highlights the importance of a diverse and balanced gut microbiota for human health, while emphasizing the need for further understanding of the impact of indoor microbiome and metabolites on gut microbiota.

21 May 2023

Analyzing impact of phospholipase D on the host immune response to A. fumigatus infection

Announcing a new article publication for Zoonoses journal. Aspergillus fumigatus infection in the lungs is accompanied by the recruitment of innate immune cells, phagocytosis, and the release of inflammatory factors.

11 May 2023

How antiviral host responses create a lung environment susceptible to bacterial and fungal infections

A recent study discussed coinfections in the lungs and how viral infections create a favorable environment for bacteria and fungi.

8 May 2023

Understanding human mycobiome commensalism and pathogenesis

Researchers explored commensalism and pathogenesis relationships in the human mycobiome.

18 Apr 2023

Is depression associated with gut mycobacteria dysbiosis in children?

Researchers evaluated the gut mycobiota in adolescents/children with depression.

4 Apr 2023

Plastic waste's 'plastisphere' could harbor and spread eukaryotic pathogens

A recent study reviews the potential for helminth, fungal, and protozoan pathogens to associate with plastisphere.

3 Apr 2023

How can microbiota be used to make wine more health beneficial?

Researchers discussed the use of wine microbiota in enhancing the functional components of wine during production.

27 Mar 2023

The role of the fungal mycobiome in women's health

Researchers discuss the association between human mycobiota and female health.

15 Mar 2023

A review of innate immunity relevant to SARS-CoV-2 and COVID-19

In a recent study published in The New England Journal of Medicine, researchers reviewed selected acute-phase proteins concerning their production, structure, and function.

7 Feb 2023