Atomic Force Microscopy News and Research

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Atomic force microscopy is a type of scanning probe microscopy used to image the surface of a substance, but at an atomic level. It can map the surface structure of different substances to understand how different structures interact with each other. This is done using a cantilever, which is similar to a vinyl record needle.

Combination of techniques reveals molecular changes in osteoarthritis

Osteoarthritis is the most common degenerative joint disease, affecting 22% of adults over 40 globally. Although the condition has been extensively studied through a medical perspective, the molecular changes associated with osteoarthritis remain unclear.

5 Jul 2023

Study reveals how p62 bodies control redox-independent stress response

Cellular stress, or oxidative stress, occurs when there is a buildup of reactive oxygen species (ROS), which interferes with cellular mechanisms and can even cause damage to proteins, lipids, and DNA.

12 Jun 2023

Fine-tuning cell mechanics stimulates hair growth: Study

Just as people's joints can get stiff as they age and make it harder for them to move around, hair follicle stem cells also get stiff, making it harder for them to grow hair, reports a new Northwestern Medicine study.

6 Jun 2023

Transforming antibiotic resistance testing: a novel, rapid and affordable technique

News Medical speaks with Dr. Sandor Kasas, a lead researcher at Ecole Polytechnique Fédérale de Lausanne in Switzerland.

19 May 2023

Ultra-long protein fibrils are a signature of severe Alzheimer’s disease, study shows

During the course of Alzheimer's disease, protein fibrils appear in the spinal fluid of affected individuals. Empa researchers, together with the Department of Neurology at the Cantonal Hospital in St. Gallen, have now visualized the wide spectrum of protein aggregates from oligomers, protofibrils to fibrils in the spinal fluid.

9 May 2023

A possible link between aggregation of SARS-CoV-2 proteins and protein misfolding diseases

A new study in the journal Nature Communications aimed to analyze the aggregation propensity in the proteins of both SARS-CoV-2 and SARS-CoV.

21 Feb 2023

High-precision mechanical sensing system can measure in vivo biomechanical properties of tissue, single cell

Fiber sensing scientists at Shenzhen University have developed a compact fiber optical nanomechanical probe (FONP) for measuring in vivo biomechanical properties of tissue and even single cell.

10 Feb 2023

Study analyzes the viability of new nanomolecule as drug delivery vehicle

A new study by the University of Barcelona has analyzed the viability of a new nanomolecule as drug delivery vehicle.

11 Jan 2023

Nanopore-based sensing device can provide volume information about tau and tubulin proteins

Tau and tubulin proteins are one of the leading causes of many neurodegenerative diseases, such as Alzheimer's and Parkinson's.

10 Jan 2023

The effects of mechanical forces on musculoskeletal cells and tissues

In this interview, Dr. Marina Danalache, Lab leader at the Laboratory of Cell Biology, Department of Orthopedic Surgery, University of Tübingen talks to News-Medical Life Sciences about the ongoing research on the effects of mechanical forces on musculoskeletal cells and tissues, as well as how these forces mediate homeostasis and drive pathophysiological processes.

From Bruker BioAFM 30 Nov 2022

Collaboration aims to investigate ARTIDIS technology as novel treatment-optimization tool for solid tumors

The University of Texas MD Anderson Cancer Center and ARTIDIS AG today announced a strategic alliance to investigate ARTIDIS technology as a novel treatment-optimization tool for patients with solid tumors in several distinct indications.

3 Oct 2022

New dental coating replicates the composition and microstructure of natural enamel

Scientists have perfected hydroxyapatite, a material for mineralizing bones and teeth. By adding a complex of amino acids to hydroxyapatite, they were able to form a dental coating that replicates the composition and microstructure of natural enamel.

16 Sep 2022

Researchers unravel the mechanism of teixobactin at the atomic level

Researchers explored the mechanisms underlying the bactericidal action of teixobactin at an atomic level.

8 Aug 2022

Researchers identify mechanistic principles for engineering antibodies to enhance cadherin adhesion

Future treatments for advanced cancer could work by sticking cancer cells in place and preventing their spread around the body. A new study by researchers at the University of California, Davis, and the University of Washington shows how an antibody strengthens bonds between cells. The work is published Aug. 3 in Proceedings of the National Academy of Sciences.

5 Aug 2022

Researchers develop new kind of Atomic Force Microscopy probes in true 3D shapes

A team of researchers from NYU Abu Dhabi's Advanced Microfluidics and Microdevices Laboratory (AMMLab) have developed new kind of Atomic Force Microscopy (AFM) probes in true three-dimensional shapes they call 3DTIPs. AFM technology allows scientists to observe, measure, and manipulate samples and micro and nanoscale entities with unprecedented precision.

26 Jul 2022

Researchers use high-speed atomic force microscopy to explore the binding mechanism of cadherins

Cell, tissue, and organ structure is maintained by cell-cell adhesion molecules that connect opposing cells. Cadherins are a class of essential cell-cell adhesion molecules for tissue formation and integrity, and defects in cadherin function cause various diseases (e.g., cancer invasion).

19 Jul 2022

Atomic Force Microscopy News and Research

Further Reading

Combination of techniques reveals molecular changes in osteoarthritis

Study reveals how p62 bodies control redox-independent stress response

Fine-tuning cell mechanics stimulates hair growth: Study

Transforming antibiotic resistance testing: a novel, rapid and affordable technique

Ultra-long protein fibrils are a signature of severe Alzheimer’s disease, study shows

A possible link between aggregation of SARS-CoV-2 proteins and protein misfolding diseases

High-precision mechanical sensing system can measure in vivo biomechanical properties of tissue, single cell

Study analyzes the viability of new nanomolecule as drug delivery vehicle

Nanopore-based sensing device can provide volume information about tau and tubulin proteins

The effects of mechanical forces on musculoskeletal cells and tissues

Collaboration aims to investigate ARTIDIS technology as novel treatment-optimization tool for solid tumors

New dental coating replicates the composition and microstructure of natural enamel

Researchers unravel the mechanism of teixobactin at the atomic level

Researchers identify mechanistic principles for engineering antibodies to enhance cadherin adhesion

Researchers develop new kind of Atomic Force Microscopy probes in true 3D shapes

Researchers use high-speed atomic force microscopy to explore the binding mechanism of cadherins

UCLouvain discovery could counter SARS-CoV-2 virus independently of the mutations

The preclinical potential of a herb used in traditional Chinese medicine for the treatment of COVID-19

Quantum dot biomimetic for SARS-CoV-2 examines neurovascular dysregulation related to brain inflammation

The preclinical potential of S. miltiorrhiza extracts for the treatment of COVID-19

How to use Atomic Force Microscopy in Life Sciences eBook

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