Cardiometabolic News and Research

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Spermidine boosts key cellular processes linked to aging in early research

This review finds that spermidine supports autophagy, mitochondrial function, and healthspan in experimental models, while observational studies link higher dietary intake to lower mortality. However, human trials have produced limited and mixed results, leaving its clinical role in healthy aging unresolved.

23 Jul 2026

Urbanization reshapes gut microbiomes across diverse South Asian communities

Urbanization is one of the most consequential demographic shifts of the 21st century. As communities move from traditional or rural to urbanized ways of life, changes in diet, lifestyle, and environmental exposures can influence many aspects of human biology and health.

22 Jul 2026

Frequent TV watching links to higher white matter lesion volume

ARIC researchers linked self-reported TV watching and occupational sitting in midlife with brain MRI measures obtained roughly 24 years later in 1,712 adults without dementia. Frequent TV watching was associated with greater white matter hyperintensity volume and lower volumes in several brain regions, while sitting at work was associated with lower white matter hyperintensity volume and larger selected cortical volumes.

22 Jul 2026

Childhood ultra-processed food intake associates with altered insulin responses

Researchers analyzed dietary and metabolic data from 508 nondiabetic Mexican American children in the SAFARI family cohort, finding that higher ultra-processed food scores were associated with lower insulin sensitivity and altered early insulin secretion measures. The exploratory cross-sectional study did not establish causality, and its multiple comparisons, historical dietary data, and questionnaire-based UPF estimates warrant confirmation in longitudinal studies and trials.

21 Jul 2026

Study tests chronotype’s liver link and finds no significant association

Researchers found no significant association between chronotype and FibroScan-derived liver fat or stiffness in 119 medication-naïve adults with overweight or obesity. The exploratory findings cannot exclude smaller effects, particularly for fibrosis, and require confirmation in larger longitudinal studies.

21 Jul 2026

Daily polypill significantly improves cardiac function in heart failure patients

Treatment with a "polypill" that combines multiple medications into a single daily dose significantly enhanced cardiac function and reduced hospitalizations for patients with heart failure, according to a study led by Michigan Medicine and UT Southwestern Medical Center.

20 Jul 2026

Increasing fruit and vegetable intake can decrease cardiovascular disease risk

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Low consumption of fruits and vegetables (FV) is a major preventable contributor to cardiovascular disease (CVD).

20 Jul 2026

High doses of caffeine from energy drinks cause cardiovascular harm

Previous studies have found that caffeine is the world's most popular stimulant and psychoactive substance, and coffee is the most common way people consume caffeine.

20 Jul 2026

Chrononutrition shows promise for postpartum weight management

New research has found that eating habits that align most closely with a woman's existing routine show promise for losing postpartum baby weight, especially for mothers earlier in the postpartum period.

20 Jul 2026

Diet helps people lose weight regardless of genetic obesity risk

A study reveals dietary coaching aids weight loss equally in individuals with high and low genetic obesity risk, challenging genetic determinism in weight loss.

17 Jul 2026

WHO updates guidelines to reduce risk of dementia worldwide

The World Health Organization (WHO) today released updated guidelines on reducing the risk of cognitive decline and dementia, providing countries with evidence-based recommendations to help prevent or delay the onset of dementia across the life course.

16 Jul 2026

Breast and prostate cancer survival worsens with metabolic syndrome

A SEER-Medicare analysis of more than 200,000 adults aged 66 and older found that metabolic syndrome was associated with about twice the adjusted hazard of death from any cause after breast or prostate cancer. The condition was also linked to higher cancer-specific, cardiovascular-specific, and liver-failure-specific mortality, although the observational design prevents causal conclusions.

14 Jul 2026

Experts urge Mexico to integrate liver disease into chronic care

Liver disease may affect close to half of adults in Mexico, yet the country tracks it far less closely than the diabetes and obesity to which it is linked, according to a new paper by Jeffrey Lazarus, professor at the CUNY Graduate School of Public Health and Health Policy Professor (CUNY SPH), and colleagues, and released to coincide with the International Congress on Obesity taking place in Mexico City this week.

14 Jul 2026

Mitochondrial DNA mutations link to cardiometabolic parameters in metabolic syndrome

Mitochondrial DNA (mtDNA) variability, especially heteroplasmy, is believed to affect cellular immunobiogenesis, particularly in monocytes in metabolic syndrome (MetS).

14 Jul 2026

Semaglutide dose may matter more than weight loss for heart health

The study shows semaglutide's cardiovascular benefits are more closely tied to attained dose than weight loss, challenging existing treatment assumptions.

14 Jul 2026

Global study reveals country-specific patterns in dementia risk factors

A major, USC-led study of more than 214,000 older adults across 14 countries and regions finds that the most common controllable risk factors for dementia - such as low education, high blood pressure and smoking - vary widely from country to country, meaning a one-size-fits-all approach to prevention won't work everywhere.

12 Jul 2026