Cell Nucleus News and Research

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Epigenetic drift explains why the aging intestine becomes more vulnerable to cancer

Researchers from the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Jena, Germany, the Molecular Biotechnology Centre (MBC) in Turin and the University of Turin, Italy, have discovered a fundamental mechanism of aging in the gut.

28 Nov 2025

New fluorescent sensor allows scientists to watch DNA damage and repair in real time

Cancer research, drug safety testing and ageing biology may all gain a major boost from a new fluorescent sensor developed at Utrecht University.

20 Nov 2025

Uppsala researchers develop Trojan horse approach for medulloblastoma treatment

The malignant pediatric brain tumor medulloblastoma is driven by proteins deep within the cancer cells, for which there are often no effective drugs available.

10 Nov 2025

Hidden cell structures reveal a common weakness in leukemia

A hidden structure inside the cell is rewriting how scientists understand leukemia. Beneath the microscope, what looked like disorder turned out to follow a simple physical rule – one that connects several major mutations behind the disease.

4 Nov 2025

Novel 3D chromosome mapping method can reliably reveal hidden structural variants

Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can reliably reveal these hidden structural variants and lead to new discoveries.

29 Oct 2025

New study reveals how the glucocorticoid receptor forms complex structures inside cells

Drugs to treat inflammatory and autoimmune diseases - such as asthma, psoriasis, rheumatoid arthritis or Chrousos syndrome - act mainly through the glucocorticoid receptor (GR).

27 Oct 2025

Study: Common test to assess viability of IVF embryos may be flawed

A test deployed in many fertility clinics to assess the viability of embryos for use in IVF is likely to overestimate the number of embryos with abnormalities, suggests a study published today.

23 Oct 2025

Nuclear binding protein identified as key contributor to trisomy 21-related CHDs

Three copies of chromosome 21 causes Down syndrome (DS), and roughly half of children born each year in the United States with DS-approximately 2,600-also have congenital heart defects (CHDs).

22 Oct 2025

Researchers achieve proof of concept for generating eggs from somatic cells

Researchers at Oregon Health & Science University have accomplished a unique proof of concept to treat infertility by turning skin cells into eggs capable of producing early human embryos.

17 Oct 2025

Pin1 inhibitors could reduce or stop outbreaks of herpes simplex virus 1

A class of antivirals called Pin1 inhibitors could reduce or stop outbreaks of herpes simplex virus 1 (HSV-1), the common infection behind oral herpes, according to new research published in Antiviral Research on July 25.

17 Oct 2025

New insights reveal persistent genome structure during cell division

Before cells can divide, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material.

17 Oct 2025

Cyclic peptide nanotubes offer new route to overcome cancer drug resistance

A research team at CiQUS (University of Santiago de Compostela, Spain) has unveiled an innovative molecular approach that enables anticancer drugs to reach the nucleus of tumor cells, where they can exert their therapeutic effect.

10 Oct 2025

Microplastics pose potential risks to bone health

The production and use of over 400 million tons of plastic each year has polluted beaches, rivers, and even the deepest parts of the ocean, reaching depths of up to 11,000 meters.

18 Sep 2025

Origin-recognition complex plays a broad role in the regulation of gene expression

Origin-recognition complex, or ORC, plays an unexpectedly broad role in the regulation of human cell gene expression, according to a study in the journal Cell Reports.

14 Aug 2025

Researchers unveil drug complex that makes cancer cells self-report to immune system

Two junior research groups at Ruhr University Bochum, Germany, have developed a drug complex that kills cancer cells in such a clever manner that they raise a red flag as they die. They signal to the immune system that something is seriously wrong with this type of cell.

18 Jul 2025

Uncovering the hidden architecture of the genome in three dimensions

In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be helpful for learners to begin with the linear presentation of how stretches of DNA form genes, this oversimplification undersells the significance of the genome's 3D structure.

12 Jul 2025

Cell Nucleus News and Research

Epigenetic drift explains why the aging intestine becomes more vulnerable to cancer

New fluorescent sensor allows scientists to watch DNA damage and repair in real time

Uppsala researchers develop Trojan horse approach for medulloblastoma treatment

Hidden cell structures reveal a common weakness in leukemia

Novel 3D chromosome mapping method can reliably reveal hidden structural variants

New study reveals how the glucocorticoid receptor forms complex structures inside cells

Study: Common test to assess viability of IVF embryos may be flawed

Nuclear binding protein identified as key contributor to trisomy 21-related CHDs

Researchers achieve proof of concept for generating eggs from somatic cells

Pin1 inhibitors could reduce or stop outbreaks of herpes simplex virus 1

New insights reveal persistent genome structure during cell division

Cyclic peptide nanotubes offer new route to overcome cancer drug resistance

Microplastics pose potential risks to bone health

Origin-recognition complex plays a broad role in the regulation of gene expression

Researchers unveil drug complex that makes cancer cells self-report to immune system

Uncovering the hidden architecture of the genome in three dimensions

Scientists identify key role of T-bet in flu memory B cells

Researchers uncover molecular switch controlling DNA packing in cell division

Mitochondria depletion in stem cells offers insights into cellular energy and evolution

Yeast cell division found to begin inside the nucleus

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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