Craniofacial News and Research

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Distinct transcriptomic profiles guide early development of maxillary and mandibular teeth

The interaction between genetics and tissue environment shapes how individual teeth form in different regions of the jaw.

12 Dec 2025

Maxillary nerve block may reduce perioperative opioid consumption in pediatric primary clefts

For infants undergoing cleft palate surgery, local anesthetic injection targeting the maxillary nerve of the face may reduce or eliminate the need for opioid medications to control postoperative pain, reports a study in The Journal of Craniofacial Surgery.

12 Dec 2025

Machine learning reveals dental caries heterogeneity in NHANES

A new article published in the Journal of Dental Research explores the development an integrated data-cleaning and subtype discovery pipeline using unsupervised machine learning for comprehensive analysis and visualization of data patterns in the National Health and Nutrition Examination Survey (NHANES) database.

11 Dec 2025

Study reveals early mandibular catch-up growth in infants with Robin sequence

Robin sequence is characterized by micrognathia, glossoptosis, and often cleft palate, leading to airway obstruction and feeding challenges.

26 Nov 2025

Two analgesic drugs may one day be repurposed as anti-tumor therapies

Peripheral afferent neurons - nerves that send signals from all areas of the body to the central nervous system (brain and spinal cord) - are known to infiltrate and grow within malignant bone tumors called osteosarcomas, often accompanied by severe pain.

29 Oct 2025

Mediterranean diet linked to better gum health

People living in the UK and following a diet close to the Mediterranean diet are more likely to have better gum health, with potentially lower amounts of gum disease and inflammation.

15 Sep 2025

HPV-DeepSeek shows promise for early detection of head and neck cancer

Human papilloma virus (HPV) causes around 70% of head and neck cancers in the United States, making it the most common cancer caused by the virus, with rates increasing each year.

9 Sep 2025

Unlocking the secrets of oral bacteria to fight tooth decay

If Wenjun Zhang has her way, no one will ever have to brush or floss again.

5 Sep 2025

Most adults experience dental fear and show interest in virtual fear-treatments

Nearly three out of four adults fear going to the dentist, according to a new study published in the Journal of the American Dental Association.

2 Sep 2025

Insights into clinical features and genetic variants of Cornelia de Lange syndrome in China

Cornelia de Lange syndrome (CdLS) is a rare genetic disorder with symptoms, including facial anomalies (such as fused eyebrows, short nose, upturned nose tip, and downturned mouth corners), growth retardation, small head (microcephaly), developmental delays, cognitive impairments, excess hair growth, and limb anomalies.

29 Aug 2025

SNAP25 identified as key to sour taste perception and cell survival

The tongue contains numerous taste buds-tiny sensory organs responsible for detecting taste. Taste buds consist of specialized cells that translate chemical stimuli into neural signals.

19 Aug 2025

Arginine dentifrices reduce dental caries in children with active caries

The International Association for Dental, Oral, and Craniofacial Research (IADR) and the American Association for Dental, Oral, and Craniofacial Research (AADOCR) have announced the publication of a new study in JDR Clinical & Translational Research that demonstrates that arginine dentifrices reduce dental caries in children with active caries as much as, or more than, a sodium fluoride dentifrice, depending on the arginine concentration.

13 Aug 2025

How early immune challenges influence oral and systemic health in children

Once viewed only as infectious invaders, bacteria are now understood to play an important role in overall health.

8 Aug 2025

E-scooter riders are three times more likely than cyclists to end up in hospital, study shows

Stand-up electric scooter riders in Helsinki are over three times more likely than cyclists to sustain injuries requiring emergency care, with head trauma and alcohol use significantly more common in scooter crashes. Helmet use among scooter riders remains exceptionally low.

30 Jul 2025