Electrophysiology News and Research

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New consensus statement updates guidelines for cardiac device lead management

New evidence on cardiovascular implantable electronic devices (CIED) lead management and the burgeoning development of new CIED technologies have contributed to the field's rapid evolution in the last decade.

25 Apr 2026

Fitness in midlife extends health span and overall life expectancy

How fit you are in midlife may help determine not just how long you live, but how many of those years are spent in good health, according to a new study published today in the JACC, the flagship journal of the American College of Cardiology.

22 Apr 2026

Brain pathways combine memory and reward to guide behavior

New research from the University of Maryland, Baltimore County (UMBC) reveals how two different parts of the brain's memory center team up in a key reward region to help mice-and likely humans-combine memories of places and contexts with the drive to pursue rewards.

10 Apr 2026

Researchers develop low-cost scalable sensors to study genetic brain disorders

Researchers have demonstrated a new class of low-cost, scalable sensors that can be used to monitor electrical activity in human cerebral organoids.

2 Apr 2026

4D digital heart model transforms treatment for heart failure patients

A made-in-Calgary 4D heart model is transforming treatment for heart failure patients having a specialized pacemaker inserted, called cardiac resynchronization therapy (CRT).

24 Mar 2026

Study maps gene activity linked to neurotransmission in living brains

Researchers have identified a distinct and reproducible gene expression program associated with neurotransmission in the living human brain, offering unprecedented insight into the molecular mechanisms that support human cognition, emotion, and behavior.

16 Mar 2026

New review reveals complex polygenic architecture underlying common epilepsies

An insightful mini-review published in Genomic Psychiatry synthesizes the rapidly expanding landscape of molecular genetic research on common epilepsies, assembling evidence from genome-wide association studies, whole-exome sequencing projects, and advanced statistical modeling to illuminate the polygenic architecture that underpins these heterogeneous neurological disorders.

10 Mar 2026

Brain organoids show goal-directed learning in control task

Imagine balancing a ruler vertically in the palm of your hand: you have to constantly pay attention to the angle of the ruler and make many small adjustments to make sure it doesn't fall over. It takes practice to get good at this.

19 Feb 2026

Ancient mind body practice matches walking for hypertension control

High blood pressure is one of the leading preventable risk factors for heart disease. Clinical guidelines recommend regular physical activity, yet long-term adherence to exercise programs is challenging for many people, particularly when routines require equipment, dedicated space, gym memberships or ongoing supervision.

18 Feb 2026

Whole-heart mapping captures arrhythmias in a single heartbeat

The UPV and Corify Care present the first whole-heart mapping technology that provides a comprehensive view of cardiac arrhythmias in a single heartbeat.

13 Feb 2026

Healthy low-carbohydrate and low-fat diets may improve cardiovascular health

The quality of a low-carbohydrate or low-fat diet may matter more than the amount of carbohydrates or fat consumed when it comes to reducing heart disease risk, according to a new study published in JACC, the flagship journal of the American College of Cardiology.

11 Feb 2026

Moderate exercise lowers atrial fibrillation recurrence after ablation

New research from CU Anschutz scientists suggests that staying physically active after heart rhythm treatment may significantly reduce the risk of atrial fibrillation (AF) returning, offering patients a simple, low-cost way to support long-term heart health.

7 Feb 2026

Molecular signature of sleeping nociceptors offers new pain targets

Researchers from the Centre for Addiction and Mental Health (CAMH) and the Institute of Neurophysiology at Uniklinik RWTH Aachen in Germany have deciphered the molecular signature of so-called sleeping nociceptors-a type of pain-sensing nerve cell that normally remains quiet and does not respond to touch or pressure, but can become overactive and drive chronic pain.

4 Feb 2026

Scientists identify a molecular switch that controls water flow in the gut

Although constipation and diarrhea may seem like opposite problems, they both hinge on the same underlying issue: how much fluid moves into the gut. These common issues affect millions of people in the U.S. each year, yet scientists have not fully understood what regulates intestinal fluid balance.

9 Jan 2026

Integrated neural probes reveal dopaminergic control of sleep-wake transitions

Understanding the dynamic neural mechanisms of sleep-wake cycles is a major challenge in sleep science and neuroengineering.

6 Jan 2026

Small shifts in blood sodium may influence human brain excitability

This exploratory study in healthy young adults found that plasma sodium levels within the normal clinical range are significantly associated with resting motor threshold, an indirect measure of corticospinal excitability. Lower sodium concentrations were linked to lower thresholds, suggesting subtle physiological variation in electrolytes may relate to interindividual differences in brain excitability.

1 Jan 2026

Study reveals how brain protein KCC2 influences reward learning

A new finding from researchers at Georgetown University Medical Center shows that the learning process of associating cues with rewards can be altered by increased or decreased activity of a specific protein in the brain.

9 Dec 2025

New evidence supports ablation for high-risk patients with AFib and sleep apnea

Obstructive sleep apnea and atrial fibrillation are two conditions that share a potentially deadly link. Having one increases the odds of developing the other, and together, the breathing difficulties of sleep apnea combined with the irregular heartbeat of atrial fibrillation (AFib) can result in life-threatening cardiovascular risks.

1 Dec 2025

Digital and AI innovations in cardiology take center stage at ESC Digital & AI Summit

Smartphone stethoscopes, voice-detected heart failure, training using 3D-printed and virtual hearts and early detection of cardiovascular disease using blood spots are among the innovations being presented at the ESC Digital & AI Summit taking place in Berlin, Germany, 21–22 November.

21 Nov 2025

Tirzepatide reveals a brain signal that predicts returning food preoccupation

Researchers implanted electrodes in the human nucleus accumbens to track brain activity during severe food preoccupation in an individual taking tirzepatide. They found that a delta–theta biomarker disappeared during symptom-free periods and re-emerged weeks before relapse, suggesting a possible neural marker of vulnerability to dysregulated eating.

18 Nov 2025