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ReproNovo announces first participant dosed in EU Phase 2 trial of RPN-002 for embryo implantation

ReproNovo, a clinical-stage biopharmaceutical company committed to addressing critical gaps in male and female fertility as well as women’s health, today announced that the first participant has been dosed in the Company’s EU Phase 2 clinical trial of RPN-002, entitled Nolasiban Optimized Regimen Dosing for Inhibition of Uterine Contractility (NORDIC).

6 Jul 2026

Uterine aging may reduce donor egg pregnancy success after 49

A major new study suggests that age-related changes in the uterus may contribute to poorer pregnancy outcomes, with women aged 49 and over experiencing lower live birth rates and higher miscarriage risk despite donor-oocyte treatment.

5 Jul 2026

European survey reveals strong public support for fertility treatment

A new Europe-wide survey launched during the 42nd Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE) suggests broad public support for fertility treatment and several areas of reproductive research, while highlighting key areas where public understanding and opinion continue to develop.

5 Jul 2026

Researchers advance fertility options for childhood cancer survivors

Researchers at Karolinska Institutet have demonstrated that it is possible to create early germ cells from preserved testicular tissue of young boys facing cancer therapy.

3 Jul 2026

Discovery provides key insights into cellular mechanisms underlying female fertility

Female fertility depends on the successful growth and maturation of eggs (oocytes) within ovarian follicles. Within these follicles, the oocyte is surrounded by granulosa cells that supply nutrients, signaling molecules, and structural support essential for egg development.

2 Jul 2026

Study finds early-onset Parkinson’s burden has more than doubled worldwide

A GBD 2021 analysis of 204 countries and territories found that early-onset Parkinson’s disease burden among people aged 20 to 49 more than doubled from 1990 to 2021. Age-standardized incidence, prevalence, and disability rates rose globally, with higher estimated burden among males, rapid growth in middle and high-middle SDI regions, and moderate ecological correlations with pesticide use.

1 Jul 2026

Study finds two effective therapies for common childhood eating disorder

The first randomized, controlled trial for a common childhood eating disorder has shown how therapists and parents can help those struggling with the condition, known as avoidant restrictive food intake disorder, or ARFID.

29 Jun 2026

Rare pelvic schwannoma removed with nerve-sparing laparoscopic surgery

Through interdepartmental collaboration, a young woman's quality of life and ability to walk were restored following the laparoscopic removal of a rare, benign tumor of neurological origin in the lesser pelvis, known as a schwannoma (also called a neurinoma).

26 Jun 2026

New protocol identifies sperm biomarkers to diagnose male infertility

Researchers from the EHU-University of the Basque Country have developed a robust protocol to detect the molecules involved in the metabolic reactions of sperm.

26 Jun 2026

Base editing technique reveals crucial gene for early human development

Research led by the University of Cambridge Loke Centre for Trophoblast Research has shown that a genome editing technique can be used to alter a single gene in human embryonic cells, enabling the study of very early human development in unparalleled detail.

25 Jun 2026

Immunotherapy may help women with early ovarian insufficiency to conceive babies

A pilot study from Karolinska Institutet shows that immunotherapy may enable stimulation of egg maturation in women with autoimmune POI (premature ovarian insufficiency) – a condition that usually leads to infertility.

24 Jun 2026

Study outlines legal challenges for fetal tissue research in Japan

Human fetal tissue research has contributed to advances in developmental biology, the study of congenital diseases, regenerative medicine, and vaccine development.

24 Jun 2026

Most IVF add-ons lack evidence of fertility benefits

There is a lack of evidence to suggest the majority of in vitro fertilization (IVF) add-ons improve fertility in patients undergoing IVF, according to a systematic review and meta-analysis published in The Lancet Obstetrics, Gynaecology, & Women's Health journal.

24 Jun 2026

Fertility preservation access remains unequal for young female cancer patients

A new Columbia University School of Nursing systematic review reveals access to fertility preservation (FP) care remains limited and unequal for girls and young women with cancer.

23 Jun 2026

New guidance to help adolescents and young adults living with and beyond cancer

Adolescents and young adults (AYA) living with and beyond cancer have unique needs and perspectives that clinicians should be aware of when providing health care.

22 Jun 2026

Psychologist warns DNA testing kits can bring unexpected risks

DNA testing kits are often gifted for Father's Day, Christmas and special occasions. The idea of learning more about yourself and unearthing some long-forgotten family history is certainly appealing for many, but a psychologist has warned that these presents can come with profound psychological implications.

19 Jun 2026

PMOS rethink reframes a common hormone disorder as a whole-body disease

A new review reframes PCOS, now proposed as PMOS, as a systemic endocrine and metabolic disorder shaped by genetic, epigenetic, ovarian, metabolic, and neuroendocrine pathways. It highlights why inconsistent diagnosis and symptom-focused care have limited progress, while targeted therapies, biomarkers, machine learning, and organ-on-chip models may support more personalized treatment.

18 Jun 2026

Men's fertility-friendly underwear may be briefs without benefits

A narrative review found that tight-fitting underwear may modestly raise scrotal temperature and is inconsistently linked to lower sperm production measures. However, current evidence does not show that switching to looser underwear improves real-world fertility outcomes.

17 Jun 2026

GLP-1s may improve testosterone levels and sperm quality in men with obesity

GLP‑1s do not harm male hormones or fertility after long-term use, according to a study being presented Monday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

15 Jun 2026

New blueberry-sized ingestible sensor tracks internal body temperature

In a hospital or at home, temperatures are usually taken using an oral or forehead thermometer, but these do not always accurately reflect the core body temperature.

15 Jun 2026