Glycans News and Research

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Study reveals how beneficial gut microbe breaks down mucus for health

A microbe found in the lower part of the gut that is associated with good health has been comprehensively analyzed and found to have a focused diet breaking down sugars locked away in mucus.

31 Jan 2025

New strategy revolutionizes glycoproteomics research

Protein glycosylation is a fundamental biological process that regulates various cellular functions, yet its study has been hampered by the complexity and low abundance of glycoproteins.

26 Dec 2024

Bovine H5N1 influenza shows potential for human adaptation through key mutations

Recent study reveals H5N1 mutations enhancing human receptor binding, highlighting pandemic risks and the need for vigilant surveillance of influenza strains.

9 Dec 2024

Innovative tissue expansion technique transforms conventional microscopy capabilities

A classical way to image nanoscale structures in cells is with high-powered, expensive super-resolution microscopes. As an alternative, MIT researchers have developed a way to expand tissue before imaging it - a technique that allows them to achieve nanoscale resolution with a conventional light microscope.

12 Oct 2024

Researchers develop technology to change protein identity in vivo

Researchers at the RIKEN Cluster for Pioneering Research (CPR) have developed technology that can alter, within the body, the recognized identity of proteins. The innovation, published in Nature Communications on October 2, allowed researchers to target mouse tumors with a protein and then transport that protein out of the body.

3 Oct 2024

Discovery of antibodies that boost complement activation against K. pneumoniae

Researchers investigate antibody-dependent complement activation during Klebsiella pneumoniae infection.

30 Sep 2024

Breakthrough in artificial sugars could revolutionize disease diagnosis and treatment

Scientists have found a way to create artificial sugars that could lead to better ways to diagnose and treat diseases more accurately than ever before.

16 Sep 2024

The surprising role of RNA in immune interactions

In a groundbreaking exploration of cell surface biology, Ryan Flynn has uncovered a surprising role for RNA outside the confines of the cell. Flynn's research, which focuses on the biology of cell surface RNA, led to the discovery that certain RNAs are chemically linked to glycans - complex carbohydrate polymers found on the cell surface.

22 Aug 2024

New research identifies key protein complex in cellular quality control

Anyone who's tried to neatly gather a fitted sheet can tell you: folding is hard. Get it wrong with your laundry and the result can be a crumpled, wrinkled mess of fabric, but when folding fails among the approximately 7,000 proteins with an origami-like complexity that regulate essential cellular functions, the result can lead to one of a multitude of serious diseases ranging from emphysema and cystic fibrosis to Alzheimer's disease.

12 Aug 2024

Novel device uses a simple blood test to detect early stage lung cancer

University of Queensland researchers have designed a device that uses a simple blood test to detect early stage lung cancer.

10 Jul 2024

Exploring PRM-A as a novel glycan-targeted therapy for SARS-CoV-2 inhibition

HIV, Ebola and most recently, COVID-19 viruses have had an enormous impact on our societies world-wide.

4 Jul 2024

AI model increases the potential for detecting cancer through sugar analyses

Researchers at the University of Gothenburg have developed an AI model that increases the potential for detecting cancer through sugar analyses

1 Jul 2024

FAU researchers receive grants to tackle Alzheimer's disease

Three Florida Atlantic University researchers at the forefront of Alzheimer's disease (AD) research have each received a $350,000 grant from the Florida Department of Health's "Ed and Ethel Moore Alzheimer's Disease Research Program."

8 May 2024

Modified sugar molecules boost stem cell therapy for brain repair after cardiac arrest

Researchers at the University of Maryland School of Medicine (UMSOM) have identified an innovation in stem cell therapy to regenerate neural cells in the brain after cardiac arrest in an animal model.

6 May 2024

Glycoengineered stem cells enhance brain recovery after cardiac arrest, study finds

Researchers at the University of Maryland School of Medicine have identified an innovation in stem cell therapy to regenerate neural cells in the brain after cardiac arrest in an animal model.

2 May 2024

Researchers unveil unique autoantibody profiles in rheumatoid arthritis patients

Patients with rheumatoid arthritis (RA) all have a unique and diverse set of antibodies that are involved in the development of the disease.

2 May 2024

New blood test shows promise in early detection of ovarian cancer

A study reveals that glycoproteins in blood could be key biomarkers for early detection and staging of epithelial ovarian cancer, potentially allowing diagnosis through a simple blood test.

28 Apr 2024

Breast milk's secret weapon against RSV revealed in new study

Researchers explored how human milk oligosaccharides (HMOs) protect infants from respiratory syncytial virus (RSV), suggesting that these components in breast milk may prevent or reduce the severity of RSV infections through multiple mechanisms including gut microbiome modulation and direct antiviral actions.

15 Apr 2024

Rethinking the germ theory: A balanced take on microbes and disease outcomes

Review explores the complexities of infectious disease outcomes through a balanced perspective, emphasizing the interplay between pathogenic microbes and host conditions, challenging the traditional germ-disease theory by proposing a more integrated view that considers both pathogen virulence and host immunity's impact on disease manifestation.

10 Apr 2024

Sugar abnormalities in the blood may promote biological aging and inflammation in HIV patients

The Wistar Institute's associate professor Mohamed Abdel-Mohsen, Ph.D., along with his team and collaborators, has identified sugar abnormalities in the blood that may promote biological aging and inflammation in people living with HIV (PLWH).