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Heroin is a very addictive chemical called diacetylmorphine. Heroin is a modified form of morphine, a highly abundant opium derived from the seedpods of the poppy plant.

Hit hard by opioid crisis, Black patients further hurt by barriers to care

Purple flags, representing the nearly 300 Mecklenburg County residents who died of opioid overdose in 2023, fluttered in the humid breeze last August in recognition of International Overdose Awareness Day on the city’s predominantly Black west side.

2 Apr 2025

Study reveals significant racial and sex disparities in drug overdose mortality rates

A recent study from Columbia University's Mailman School of Public Health reveals significant racial and sex disparities in drug overdose mortality rates.

1 Apr 2025

Researchers identify key gene linked to heroin addiction

Opioid use disorder is associated with more than 350,000 deaths annually worldwide. Guided by the need for an increased understanding of critical neurobiological features of addiction, researchers have now found a unique molecular signature and genes in the orbitofrontal cortex associated with heroin-seeking behavior.

26 Mar 2025

Chronic cocaine use increases impulsivity

Findings indicate chronic cocaine use alters brain circuits, increasing impulsivity in low-impulsive rats, contradicting previous assumptions about addiction.

5 Mar 2025

With RFK Jr. in charge, supplement makers see chance to cash in

Last fall, before being named the senior U.S. health official, Robert F. Kennedy Jr. said the Trump administration would liberate Americans from the FDA's "aggressive suppression" of vitamins, dietary supplements, and other substances — ending the federal agency's "war on public health," as he put it.

25 Feb 2025

Low-dose initiation of buprenorphine for people using fentanyl fails to deliver expected results

During the COVID-19 pandemic, when fentanyl overdoses surged, doctors were desperate to find ways of helping their patients.

24 Jan 2025

Study highlights the growing crisis of methamphetamine-related deaths in the U.S.

Methamphetamine deaths in the U.S. rose 61-fold from 1999 to 2021, according to a new study, highlighting a growing crisis in addiction and public health.

13 Jan 2025

Stimulant users are caught in fatal ‘fourth wave’ of opioid epidemic

In Pawtucket, Rhode Island, near a storefront advertising "free" cellphones, J.R. sat in an empty back stairwell and showed a reporter how he tries to avoid overdosing when he smokes crack cocaine.

3 Jan 2025

Structural and functional brain changes found in individuals with opioid use disorder

Researchers at the Yale School of Medicine found structural and functional alterations in specific brain regions of individuals with opioid use disorder.

10 Dec 2024

New insights into pain signaling could lead to better chronic pain treatment

When pain signals are passed along the nervous system, proteins called calcium channels play a key role. Researchers at Linköping University, Sweden, have now pinpointed the exact location of a specific calcium channel fine-tuning the strength of pain signals.

18 Nov 2024

California voters consider tough love for repeat drug offenders

California voters are considering whether to roll back some of the criminal justice reforms enacted a decade ago as concerns about mass incarceration give way to public anger over property crime and a fentanyl crisis that has plagued the state since the covid-19 pandemic hit.

30 Sep 2024

Higher doses of buprenorphine linked to lower emergency visits in opioid use disorder

Adults with opioid use disorder who receive a higher daily dose of the opioid addiction treatment medication buprenorphine may have a lower risk of subsequent emergency department visits or use of inpatient services related to behavioral health (such as for mental health and substance use disorders) than adults receiving the recommended dose, according to an analysis funded by the National Institutes of Health (NIH).

25 Sep 2024

Study reveals significant increase in drug overdoses in Colombia among young women

Overdose rates in Colombia involving illegal opioids, hallucinogens, stimulants and sedative psychotropic medication increased greatly during 2018-2021, mainly caused by overdoses in young women, according to a study at Columbia University Mailman School of Public Health.

12 Sep 2024

Study reveals 45% drop in oxycodone use in Australia after policy changes

Between 2018 and 2020, Australia implemented policy changes to improve the quality and safety of opioid prescribing, with a specific focus on oxycodone.

12 Sep 2024

Cannabis and hallucinogen use stayed at historically high among adults in 2023

The percentages of adults using cannabis and hallucinogens over the past year stayed at historically high levels in 2023, according to the latest findings from the University of Michigan’s Monitoring the Future survey.

29 Aug 2024

North Carolina's residential opioid treatment services lack evidence-based approaches

A new study of organizations that claim to provide residential opioid substance use services in North Carolina found that only 12% of the organizations were licensed by the state to provide residential substance use treatment. What's more, only about a quarter of the organizations even allowed patients to access the only treatment for opioid use disorder proven to reduce overdose deaths.

29 Aug 2024

Recreational drug users three times more likely to experience repeat cardiovascular events

New research presented at this year's ESC Congress 2024 in London, UK (30 Aug – 2 Sept) shows that, among patients admitted to the intensive cardiac care unit (ICCU), those with a recent history of recreational drug use are three times more likely than those with no history to experience a repeat serious cardiovascular event within one year.

28 Aug 2024

Public voices often ignored in states’ opioid settlement money decisions

The conversation wasn't sounding good for Kensington residents on June 20. The Philadelphia neighborhood is a critical center of the nation's opioid crisis, and the city had decided to spend $7.5 million in opioid settlement money to improve the quality of life there.

27 Aug 2024

Exploring the impact of xylazine on wound care needs

The animal tranquilizer xylazine is increasingly found in the illicit opioid supply nationwide, leading to severe wounds among people who use drugs. New research led by a University of Pittsburgh physician-scientist and published in Drug and Alcohol Dependence seeks to understand the wound care experiences of this population.

22 Aug 2024

Study: Drug-involved overdose deaths increased by over 500% in 2022

Drug-involved overdose deaths increased by over 500 percent in 2022 according to a study at Columbia University Mailman School of Public Health, with trends attributed to synthetic opioids.

5 Aug 2024