Mammalian Cells News and Research

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H5N1's evolutionary leap could undermine vaccines and heighten human infection risk

From egg prices to pet food recalls – and now, confirmation that another strain of bird flu has infected a large commercial flock of broiler chickens on a Mississippi farm – headlines are capturing escalating concern over H5N1's spread.

24 Apr 2025

Supercharging Next-Gen Antibody Discovery with AI and High-Throughput Experimentation

Automation and machine learning are transforming antibody discovery at LabGenius, with the EVA™ platform enabling rapid, high-throughput experimental processes.

1 Apr 2025

Exosome-mediated siRNA delivery targets antibiotic resistance in bacteria

Multidrug-resistant bacteria pose a major threat to human health. Manipulation of bacterial genes at the transcriptional level is a potential strategy to fight antibiotic-resistant bacterial infections by silencing their resistance genes.

7 Mar 2025

Duke engineers develop synthetic approach to boost bacterial protein synthesis

Biomedical engineers at Duke University have demonstrated a new synthetic approach that turbocharges bacteria into producing more of a specific protein, even proteins that would normally destroy them, such as antibiotics.

11 Feb 2025

New technology unlocks secrets of bacterial gene expression

How do bacteria - harmless ones living in our bodies, or those that cause disease - organize their activities? A new study, combining powerful genomic-scale microscopy with a technical innovation, captured which genes bacteria turn on in different situations and in different spatial environments.

6 Feb 2025

Pasteurization destroys influenza viruses in milk, reinforcing dairy safety

Pasteurization at 63°C and 72°C effectively inactivates influenza A viruses in milk, ensuring its safety for human consumption while viral RNA may still be detected.

2 Feb 2025

A new strategy for enhancing the production of protein-based drugs

An international team of researchers led by the University of California San Diego has developed a new strategy to enhance pharmaceutical production in Chinese hamster ovary (CHO) cells, which are commonly used to manufacture protein-based drugs for treating cancer, autoimmune diseases and much more.

15 Jan 2025

Human protein MxA restricts H5N1, but virus mutations raise alarms

Human MxA protein suppresses mammalian H5N1 virus replication, but emerging mutations may enable partial evasion, raising concerns for human transmission.

5 Jan 2025

Rice researchers develop new construction kit for engineering smart cells

Rice University bioengineers have developed a new construction kit for building custom sense-and-respond circuits in human cells.

3 Jan 2025

Nutrient metabolism regulates T cell exhaustion and therapy potential

Findings reveal that metabolic enzymes ACSS2 and ACLY regulate T cell exhaustion, linking nutrient metabolism to epigenetic changes in immunity.

17 Dec 2024

Nanoscale cellular interactions unveiled by the SoTILT3D imaging platform

A team of researchers led by Anna-Karin Gustavsson at Rice University has developed an innovative imaging platform that promises to improve our understanding of cellular structures at the nanoscale.

27 Nov 2024

Mitochondria’s division of labor sheds light on how cancer cells survive harsh conditions

Research shows mitochondria form distinct subpopulations under nutrient stress, revealing survival mechanisms in cancer cells and potential therapeutic targets.

12 Nov 2024

Advancing vaccine development through green biotechnology

The diseases hepatitis B (HBV) and C (HCV) remain a significant health threat worldwide, causing approximately 1.3 million deaths each year.

6 Nov 2024

Electric skin patch offers drug-free solution to bacterial infections

Using a few zaps of electricity to the skin, researchers can stop bacterial infections without using any drugs. For the first time, researchers designed a skin patch that uses imperceptible electric currents to control microbes.

24 Oct 2024

New insights on 5-fluorouracil's mechanism in different cancers

Study reveals the drug, 5-fluorouracil, acts differently in different types of cancer — a finding that could help researchers design better drug combinations.

7 Oct 2024

Molecular pathways in human cells reveal potential for developmental pause

In some mammals, the timing of the normally continuous embryonic development can be altered to improve the chances of survival for both the embryo and the mother.

26 Sep 2024

H5N1 bird flu is mutating fast and jumping to mammals - could the next pandemic be here?

Researchers reveal how H5N1 viruses rapidly adapted to mammals through genetic reassortment and specific mutations, raising concerns over potential pandemic risks. Evidence from mink, marine mammals, and dairy cattle shows mammal-to-mammal transmission.

25 Sep 2024

Enhanced TnpB protein offers new possibilities for gene editing

CRISPR-Cas is used broadly in research and medicine to edit, insert, delete or regulate genes in organisms. TnpB is an ancestor of this well-known "gene scissor" but is much smaller and thus easier to transport into cells.

23 Sep 2024

New bacterial defense mechanism revealed as potential tool for genome editing

Scientists who have described in a new study the step-by-step details of a bacterial defense strategy see the mechanism as a promising platform for development of a new genome-editing method.

29 Aug 2024

Computational tools reveal 3D structures of viral proteins

These rapid shifts mean that researchers are still trying to understand a multitude of viral proteins and precisely how they increase viruses' infecting abilities - knowledge that could be crucial for developing new or better virus-fighting treatments.

27 Aug 2024