Mass Spectrometry News and Research

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Mass spectrometry is an analytical method used to identify different compounds based on the atomic sample constitution of the molecules and their charge state, which enables “blind” analysis of an unknown sample without any prior knowledge of its composition.

Cold-exposed mothers pass metabolic protection to male rat offspring through milk

Maternal cold exposure during early pregnancy improved glucose control and reduced liver fat in male rat offspring, with benefits persisting into late adulthood. The findings implicate a breast milk LCA, gut microbiota, and Th17 immune pathway, while human cohort data showed an observational link between winter conception and lower MASLD risk.

12 Jul 2026

New noninvasive approach analyzes compounds released during cupping therapy

Cupping therapy is a traditional Chinese medicine (TCM) technique used to treat chronic pain, expedite muscle recovery, and other conditions.

9 Jul 2026

Direct-to-definitive toxicology screening: Moving beyond immunoassays in clinical toxicology

Discover expert insights into toxicology screening with mass spectrometry, reducing false results and improving patient safety in clinical toxicology.

From Waters Advanced Diagnostics 9 Jul 2026

Smoking shows no major impact on the eye microbiome in small study

A small study found no evidence that smoking causes large or consistent shifts in the ocular surface microbiome or tear proteome. The authors caution that subtle smoking-related effects cannot be ruled out, given the small cohort and the ocular surface's low-biomass, contamination-sensitive microbial niche.

8 Jul 2026

New method helps scientists better understand DNA organization

Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at NUS have developed a new method that allows scientists to better understand how DNA is organized and regulated inside our cells.

6 Jul 2026

New bacterial enzyme blueprint could accelerate cancer treatment development

A team of researchers at the University of Warwick and Monash University has solved a puzzle that's stumped drug developers for decades: how bacteria naturally create multiple versions of powerful cancer therapies.

1 Jul 2026

Botanical prebiotics may steer skin microbes toward healthier balance

Researchers tested plant-derived prebiotic candidates against selected skin-associated bacteria and found that garlic, flaxseed, and mango ginger extracts inhibited S. aureus or acne-associated C. acnes in vitro. Onion and guduchi extracts modestly promoted S. epidermidis, suggesting a microbiome-targeted skincare route that now needs validation in skin models and human studies.

30 Jun 2026

Biognosys showcases next-gen multiomics innovations at ASMS 2026

The Biognosys Group, a leader in mass spectrometry-based multiomics, announces advancements across its integrated multiomics portfolio, highlighting next-generation software, sample preparation, enrichment, and separation technologies for proteomics and metabolomics.

From Biognosys 26 Jun 2026

New protocol identifies sperm biomarkers to diagnose male infertility

Researchers from the EHU-University of the Basque Country have developed a robust protocol to detect the molecules involved in the metabolic reactions of sperm.

26 Jun 2026

Study uncovers mechanism driving metastasis in aggressive gastric cancer

A study recently published in Current Molecular Pharmacology has uncovered a novel mechanism by which the long non‑coding RNA PVT1 and the translation initiation factor EIF4A1 cooperate to drive gastric cancer metastasis.

25 Jun 2026

Pioneering technique maps the proteome of individual cardiomyocytes

Two research teams at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) have developed a pioneering technique in Spain to characterize the proteome of individual cardiomyocytes-the cells responsible for heart contraction.

24 Jun 2026

Trial identifies 4 grams a day as the tested safe level for L-tyrosine in healthy men

A randomized, crossover trial in healthy adult men found that 4 weeks of L-tyrosine supplementation at doses up to 4 g/day did not cause clinically meaningful changes in safety markers, diet, blood pressure, or body measures. The highest tested dose, 4 g/day, was identified as the no-observed-adverse-effect level under the study’s four-week conditions, although broader and longer-term studies are still needed.

23 Jun 2026

Natural molecule erucamide helps slow progressive retinal degeneration

Many conditions that cause vision loss share a common feature: the gradual breakdown of the retina, the light-sensing tissue at the back of the eye.

22 Jun 2026

Optimized proximity labeling platform tracks cellular protein communication networks

The body's organs are in constant communication. Fat tissue tells the liver when to store or release energy, the immune system signals localized inflammation, and thousands of proteins carry these messages to organs throughout the body.

22 Jun 2026

New human protein atlas maps how cancer rewires the body’s tissues

Researchers created a DIA-MS atlas of 13,609 proteins across 2,856 samples from fetal, healthy adult, paired non-tumor, and tumor tissues. The resource maps tissue-specific protein patterns, cancer-associated changes, organ-specific drug-toxicity signals, and candidate therapeutic targets.

21 Jun 2026

PMOS rethink reframes a common hormone disorder as a whole-body disease

A new review reframes PCOS, now proposed as PMOS, as a systemic endocrine and metabolic disorder shaped by genetic, epigenetic, ovarian, metabolic, and neuroendocrine pathways. It highlights why inconsistent diagnosis and symptom-focused care have limited progress, while targeted therapies, biomarkers, machine learning, and organ-on-chip models may support more personalized treatment.

18 Jun 2026

Purdue develops next-generation platform to accelerate cancer drug discovery

Researchers at the Purdue Institute for Cancer Research (PICR) have developed a next-generation technology platform designed to dramatically accelerate one of the slowest and most challenging stages of cancer drug discovery: identifying promising compounds that could eventually become new therapies.

16 Jun 2026

Australia’s diphtheria outbreak shows why boosters, antibiotics, and better housing all matter

A 131-case diphtheria outbreak in Australia’s Northern Territory showed how toxigenic Corynebacterium diphtheriae can re-emerge even in highly vaccinated populations. Genomic and epidemiological evidence linked most cases to a dominant ST381 strain, with transmission shaped by overcrowding, poor skin health, and persistent health inequities.

15 Jun 2026

Urine drug test may boost adherence to blood pressure medications

The largest ever UK trial of a urine test used across the NHS to spot when patients skip their medication has shown it may improve adherence to treatment.

12 Jun 2026

Saliva biomarkers can directly detect acute sleep deprivation

A research team at the University of Zurich (UZH) has discovered biomarkers of sleep loss in saliva. Acute sleep deprivation can be detected using just a single saliva sample.

12 Jun 2026