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RNA sequencing analysis feasible for diagnosis of molecular subtypes in pediatric B-ALL

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, representing more than 30% of all pediatric cases.

29 Jan 2024

The role of glucose in inducing tolerance to amphotericin B for fungal meningitis treatment

Researchers investigate the mechanism responsible for amphotericin B tolerance of Cryptococcus neoformans.

18 Jan 2024

New study shows how brain glucose affects fungal disease treatment

Metabolite-drug-fungal interactions in the fungal meningitis pathogen Cryptococcus neoformans.

16 Jan 2024

"TimeMachine" algorithm revolutionizes circadian rhythm analysis with single blood sample

"TimeMachine," an algorithm developed by U.S. researchers, accurately predicts circadian phase from a single blood sample using gene expression, offering a novel, efficient approach to understanding circadian rhythms and their impact on health.

9 Jan 2024

Needle-free vaccine patch can protect people from deadly Zika virus

A simple-to-apply, needle-free vaccine patch is being developed to protect people from the potentially deadly mosquito-borne Zika virus.

30 Nov 2023

Genome haplarithmisis sheds light on complex genetic landscape of miscarriages

A new study published in Nature Medicine reports on a chromosomal analysis of over 1,700 spontaneous early miscarriages.

27 Nov 2023

Study shows phages can promote mammalian cellular growth and survival

Bacteriophages, also called phages, are viruses that infect and kill bacteria, their natural hosts. But from a macromolecular viewpoint, phages can be viewed as nutritionally enriched packets of nucleotides wrapped in an amino acid shell.

26 Oct 2023

Gut defenders: How T-cell intraepithelial lymphocytes guard against colon cancer

In the latest research published in Science Immunology, experts delve into the gene expression patterns of distinct intraepithelial lymphocyte populations in various gastrointestinal tract regions. Key findings reveal the roles of T-cell IELs in detecting infections and ensuring the gut's barrier integrity, with a special emphasis on their function in combating colon cancer.

9 Oct 2023

Identification of Alzheimer's disease-associated micro-RNA biomarkers through network-based analysis

Micro-ribonucleic acids (miRNAs) linked to cognition and Alzheimer's disease (AD).

3 Oct 2023

Broken String Biosciences strengthens senior leadership team to accelerate product development and commercialization

Broken String Biosciences, a genomics company building a technology platform to drive the development of cell and gene therapies that are safer by design, today announced the expansion of its senior leadership team.

From Broken String Biosciences 2 Oct 2023

Comparative genomic analysis between systemic juvenile rheumatoid arthritis and type 1 diabetes

Shared genetic markers and immune system involvement in sJRA and T1D.

15 Sep 2023

Multi-omics study offers insights into psoriasis treatment

Researchers use a multi-omics approach combining immune cell-enriched scRNA-seq, microarray analysis, and immunohistochemistry to elucidate the translational role of anti-IL-17A in suppressing the autoimmune functions of T17 cells, thereby effectively treating human psoriasis.

14 Sep 2023

Study discovers method to classify febrile illness with a single blood sample

Researchers trained machine learning (ML) models to analyze RNA molecular signatures in patients’ blood.

28 Aug 2023

Medical grade adhesives for medical device manufacturing

In this interview, Master Bond describes the features and benefits of medical grade adhesives for medical device manufacturing.

From Master Bond Inc. 8 Aug 2023

KIAA0930 could be a novel therapeutic target for cancer cachexia

A new research paper was published in Oncotarget's Volume 14 on July 20, 2023, entitled, "The uncharacterized transcript KIAA0930 confers a cachexic phenotype on cancer cells."

26 Jul 2023

Arrayjet announces collaboration with Chemspace to augment its small molecule microarray services for drug discovery

Arrayjet, a leading provider of inkjet liquid-handling solutions, today announced that it has partnered with Chemspace, the largest online catalogue of small molecules and biologics, to augment and streamline the Company’s small molecule microarray (SMM) service offering.

From Arrayjet Ltd 19 Jul 2023

Study suggests blood group A may directly influence SARS-CoV-2 infectious risk

Researchers evaluated the association between blood group A and SARS-CoV-2 infections.

29 Jun 2023

Study reveals a co-pathogenesis mechanism of acute myocardial infarction and ulcerative colitis

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Cardiovascular diseases, particularly acute myocardial infarction, are the leading cause of disability and death.

15 Jun 2023

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Research unveils the significance of uridine as a metabolic fuel in pancreatic ductal adenocarcinoma (PDA) cells under glucose-deprived conditions. Uridine utilization, mediated by uridine phosphorylase 1 (UPP1), supports redox balance, survival, and proliferation in PDA, highlighting its potential as a novel therapeutic target in the treatment of this resistant cancer.

23 May 2023

Study shows the potential of TAp63 as a new therapeutic target for rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The clinical outcomes of patients with active RA can be improved using anti-rheumatic medications, such as methotrexate (MTX).

22 May 2023