Muscle News and Research

RSS

Atorvastatin reduces major cardiovascular events but misses disability-free survival goal

Atorvastatin reduced major cardiovascular events by 30% in older people without known cardiovascular disease, diabetes or dementia, but did not significantly improve disability-free survival, according to results presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in the New England Journal of Medicine.

29 Aug 2026

Plyo-HIIT program targets healthier body composition in children

Traditional weight-loss strategies for children, from calorie restriction to general aerobic exercise, often carry an unwanted side effect: they cut fat, but they also erode muscle mass.

28 Aug 2026

Newly developed radiotheranostic pair identifies and treats renal tumors

A newly developed radiotheranostic pair, 68Ga/177Lu-NYM096, can identify tumors and effectively deliver targeted radiotherapy to patients with metastatic clear cell renal cell carcinoma (ccRCC).

28 Aug 2026

New study links gestational age to malnutrition in cerebral palsy

Malnutrition is a common concern in children with cerebral palsy (CP), a condition that can affect movement, feeding, swallowing, and independence.

28 Aug 2026

Aficamten improves symptom burden and exercise capacity in patients with non-obstructive HCM

Aficamten treatment was associated with significant improvements in symptom burden and exercise capacity in patients with symptomatic non-obstructive hypertrophic cardiomyopathy, according to results presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in the New England Journal of Medicine.

28 Aug 2026

CARDIO-TTRansform trial investigating eplontersen fails to meet primary efficacy endpoint

The CARDIO-TTRansform trial investigating eplontersen in patients with transthyretin-mediated amyloid cardiomyopathy did not meet its primary efficacy endpoint, according to results presented in a Hot Line session today at ESC Congress 2026.

28 Aug 2026

Compound PF-04457845 slows motor decline in ALS mouse models

Amyotrophic lateral sclerosis (ALS) is a severe neurological disease that destroys nerve cells responsible for muscle movement.

28 Aug 2026

Researchers tested dozens of clues for long COVID. One finding stood out

A nationwide study of 218 people in the Faroe Islands examined clinical, neurological, and blood-based markers associated with persistent symptoms around six months after SARS-CoV-2 infection. Despite extensive testing, researchers found no convincing biomarker for long COVID, while a statistical association with lower INR remained within the normal clinical range and requires replication.

27 Aug 2026

Ketogenic diet excels at reversing prediabetes and fatty liver

There is no shortage of popular diets to try, and they can generally produce weight loss if followed to the letter. But are all diet plans created equal in terms of reducing the cardiometabolic risks that come with obesity, such as Type 2 diabetes and liver disease?

27 Aug 2026

UofL receives new federal funding to advance metabolic health research

Chronic health conditions such as diabetes, obesity, heart disease and metabolic liver disease have sharply increased in recent decades and are among the most urgent health challenges facing our society.

27 Aug 2026

Study links finasteride to fewer complications after heart attack in men

Patients treated with medication for benign prostatic hyperplasia at the time of a severe acute heart attack experienced fewer serious complications from the attack, according to a study from the University of Gothenburg.

26 Aug 2026

A year after women lost weight, researchers saw which health gains lasted and which faded

Diet-induced weight loss significantly reduced predicted 10-year risks of major adverse cardiovascular events and type 2 diabetes in healthy premenopausal women with overweight, regardless of whether aerobic or resistance exercise was added. Some of these gains diminished as weight was partially regained over the following year, although greater exercise adherence was associated with less rebound in predicted diabetes risk.

25 Aug 2026

Mitochondrial transplantation helps repair donor organs during machine perfusion

Transplant medicine still depends on a limited supply of donor organs, while many retrieved grafts are discarded because ischemia, cold storage, and reperfusion can rapidly damage their cells.

25 Aug 2026

Ancient dental calculus reveals diverse diets of Japanese commoners

What did ordinary people really eat in premodern Japan, beyond the dishes described in cookbooks and the bones discarded at urban waste pits? Reconstructing past diets at the level of individual food items is remarkably difficult.

25 Aug 2026

From caffeine to trigonelline, coffee has surprising links to muscle biology

A scoping review of 54 studies found that coffee and several coffee-derived bioactive compounds influence pathways linked to skeletal muscle metabolism, including insulin signaling, mitochondrial function, oxidative stress, inflammation, glucose uptake, and protein turnover. Human studies reported associations with greater muscle mass and lower frailty or functional impairment, but most evidence remains observational or preclinical and cannot establish causality.

25 Aug 2026

The diet-Alzheimer’s connection is more complicated than “eat this, avoid that”

A mini-review finds that dietary patterns may influence Alzheimer’s disease through interconnected pathways involving neuroinflammation, insulin resistance, oxidative stress, blood-brain barrier dysfunction, homocysteine, and the gut-brain axis. The authors argue that genetics, sex, age, physical activity, and socioeconomic context may modify these relationships, supporting more individualized approaches to nutrition research and dementia prevention.

25 Aug 2026

Shared protein pathology redefines treatment for multiple neurodegenerative diseases

On the surface, amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and limbic-predominant age-related TDP-43 encephalopathy (LATE) might seem like unrelated diseases.

24 Aug 2026

New study makes progress in understanding the mechanisms behind severity of HFpEF

Approximately 3 million people in the United States are living with a condition called heart failure with preserved ejection fraction, or HFpEF.

24 Aug 2026

Multi-target interventions may yield superior outcomes for chronic ankle instability

Ankle sprain is the most prevalent sports-related injury affecting the lower limbs, and up to 70% of individuals with ankle sprain experience persistent symptoms, such as sensorimotor impairment and balance deficits, which may ultimately progress to chronic ankle instability (CAI).

24 Aug 2026

UC Berkeley researchers find new potential treatment for obesity and diabetes

Over the past five years, medications called GLP-1s have revolutionized the treatment of metabolic disorders like obesity, diabetes and fatty liver diseases.

21 Aug 2026

Muscle News and Research

Atorvastatin reduces major cardiovascular events but misses disability-free survival goal

Plyo-HIIT program targets healthier body composition in children

Newly developed radiotheranostic pair identifies and treats renal tumors

New study links gestational age to malnutrition in cerebral palsy

Aficamten improves symptom burden and exercise capacity in patients with non-obstructive HCM

CARDIO-TTRansform trial investigating eplontersen fails to meet primary efficacy endpoint

Compound PF-04457845 slows motor decline in ALS mouse models

Researchers tested dozens of clues for long COVID. One finding stood out

Ketogenic diet excels at reversing prediabetes and fatty liver

UofL receives new federal funding to advance metabolic health research

Study links finasteride to fewer complications after heart attack in men

A year after women lost weight, researchers saw which health gains lasted and which faded

Mitochondrial transplantation helps repair donor organs during machine perfusion

Ancient dental calculus reveals diverse diets of Japanese commoners

From caffeine to trigonelline, coffee has surprising links to muscle biology

The diet-Alzheimer’s connection is more complicated than “eat this, avoid that”

Shared protein pathology redefines treatment for multiple neurodegenerative diseases

New study makes progress in understanding the mechanisms behind severity of HFpEF

Multi-target interventions may yield superior outcomes for chronic ankle instability

UC Berkeley researchers find new potential treatment for obesity and diabetes

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News