Nanobodies News and Research

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Newly discovered nanobody may lead to a treatment for Retinitis Pigmentosa

A team of scientists from the University of California, Irvine, believe they have discovered a special antibody which may lead to a treatment for Retinitis Pigmentosa, a condition that causes loss of central vision, as well as night and color vision.

7 Sep 2023

Real-time monitor can detect SARS-CoV-2 in indoor air within 5 minutes

Now that the emergency phase of the COVID-19 pandemic has ended, scientists are looking at ways to surveil indoor environments in real time for viruses.

10 Jul 2023

Tiny nano-sized pores detect diseases at an earlier stage

In a collaboration with Groningen University, Professor Jørgen Kjems and his research group at Aarhus University have achieved a remarkable breakthrough in developing tiny nano-sized pores that can contribute to better possibilities for, among other things, detecting diseases at an earlier stage.

15 Jun 2023

Scientists unlock virus-fighting power with synthetic nanobody platform

Discovery and validation of nanobodies, a promising class of biologics, for viral infection prevention and treatment, including anti-SARS-CoV-2 nanobodies with enhanced neutralization properties through synergistic pairing. The study demonstrates the potential of nanobodies in developing effective therapies against viral infections.

8 Jun 2023

Study uncovers a novel fold within the SARS-CoV-2 replication co-factor non-structural protein 9

Researchers present the crystal structure of an anti-non-structural protein 9 specific nanobody in complex with the SARS-CoV-2 nsp9.

15 Apr 2023

Award-winning project uses INTEGRA pipettes for success in international genetic engineering competition

Students from the University of Groningen, Netherlands, enjoyed gold medal success at last year’s iGEM competition.

From INTEGRA Biosciences 13 Apr 2023

Probiotic E. coli secretes proteins of therapeutic value into its surroundings

Humans are colonized with thousands of bacterial strains. Researchers are now focused on genetically modifying such bacteria to enhance their intrinsic therapeutic properties.

31 Mar 2023

Researchers create the first 'living medicine' to treat drug-resistant lung infections

Researchers have designed the first 'living medicine' to treat lung infections. The treatment targets Pseudomonas aeruginosa, a type of bacteria which is naturally resistant to many types of antibiotics and is a common source of infections in hospitals.

19 Jan 2023

Structural studies pave the way for cancer drugs that could target only mutated versions

To design drugs that stall the growth of aggressive cancers, it helps to know the structures of the proteins that are revving the cancers' engines.

9 Dec 2022

Mucosal IgA fused nanobody as a non-invasive, cost-effective prophylaxis and therapeutic option against major SARS-CoV-2 variants

Researchers from the United States developed an affordable, non-invasive, inhalable prophylactic treatment consisting of immunoglobulin (Ig) A fused nanobodies against the SARS-CoV-2 Omicron variant.

2 Dec 2022

Chitin-immobilized nanobodies for SARS-CoV-2 detection

Researchers demonstrated a novel strategy to detect SARS-CoV-2 using chitin-immobilized nanobodies.

21 Nov 2022

Yeast display used to generate SARS-CoV-2 RBD-specific nanobodies

Researchers engineered biparatopic nanobodies against SARS-CoV-2.

5 Oct 2022

The potential of nanobody engineering in the development of SARS-CoV-2 antivirals and diagnostic tools

Researchers investigated nanobody engineering to develop antivirals and diagnostic tools against SARS-CoV-2.

20 Sep 2022

Plant production of nanobodies that neutralize the interaction between ACE2 receptor and SARS-CoV-2 spike protein

Researchers demonstrated the production of nanobodies against SARS-CoV-2 spike protein.

7 Sep 2022

A rapid and efficient method of identifying neutralizing nanobodies directed against SARS-CoV-2

A recent PLoS ONE study detected neutralizing nanobodies against SARS-CoV-2 from nanobody phage display libraries and via in vitro and ex vivo high-throughput screenings.

2 Sep 2022

Study reveals a vital route through which fascin promotes cancer development

The study reveals an important route through which fascin promotes cancer development and provides insights into potential pathways that could block its action.

30 Aug 2022

How effective are nanotechnology-based vaccines, drugs, and antibodies to combat variants of SARS-CoV-2?

Researchers explored how effectively nanotechnology-based novel and potential vaccines, drugs, and monoclonal antibodies could combat the current and yet to emerge SARS-CoV-2 variants.

22 Aug 2022

Rapid and efficient strategy for the development and design of SARS-CoV-2 neutralizing humanized nanobody constructs

Researchers developed humanized nanobodies that neutralize SARS-CoV-2.

16 Aug 2022

Newly developed nanobodies could eventually be used to treat neurocognitive disorders

Proteins called antibodies help the immune system find and attack foreign pathogens. Mini versions of antibodies, called nanobodies — natural compounds in the blood of animals such as llamas and sharks — are being studied to treat autoimmune diseases and cancer.

1 Aug 2022

Newly developed nanobody can get through tough brain cells and treat Parkinson’s disease

Proteins called antibodies help the immune system find and attack foreign pathogens. Mini versions of antibodies, called nanobodies - natural compounds in the blood of animals such as llamas and sharks - are being studied to treat autoimmune diseases and cancer.

28 Jul 2022