Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

Semaglutide reduces urine albumin-to-creatinine ratio in overweight chronic kidney disease patients

Researchers investigate the clinical efficacy of semaglutide in controlling urine albumin-to-creatinine ratio in overweight patients with chronic kidney disease.

31 Oct 2024

Ozempic effective for patients with chronic kidney damage

In a 24-week trial, semaglutide led to a 52% reduction in albuminuria and improved kidney health in individuals with chronic kidney disease and obesity.

28 Oct 2024

Novel gene therapy PS-002 targets podocytes in IgA nephropathy

IgA nephropathy is an autoimmune kidney disease, and complement, a component of the innate immune system, plays a role in the condition's pathogenesis.

27 Oct 2024

New trial shows felzartamab reduces proteinuria in IgA nephropathy patients

IgA nephropathy (IgAN) is an autoimmune kidney disease driven by immune cells that express a protein called CD38 on their surface.

26 Oct 2024

Reduced heart rate variability linked to higher mortality in people with diabetes

Disruption to normal variations in daily heart rate (HR) is associated with a much higher risk of dying in people with type 1 and type 2 diabetes over 21 years, according to new research to be presented at this year's Annual Meeting of The European Association for the Study of Diabetes (EASD), Madrid (9-13 Sept).

9 Sep 2024

Fasting before cardiac catheterization not necessary, study finds

There was no difference in complications in patients who fasted or did not fast before cardiac catheterization procedures requiring conscious sedation, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

2 Sep 2024

Understanding gluten's role in autoimmunity and inflammation

The interaction between humans and their environment, mediated by nutrition, plays a crucial role in regulating inflammatory responses.

21 Aug 2024

Xanthones show promise in diabetes with antioxidant and anti-inflammatory properties

Research reveals xanthones as promising agents in diabetes management, offering antioxidant, anti-inflammatory, and insulin-sensitizing benefits.

29 Jul 2024

Short and long sleep duration linked to microvascular disease in newly diagnosed diabetics

New research to be presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) (Madrid, 9-13 September) shows that people recently diagnosed with diabetes who experience short or long sleep duration are more likely to experience microvascular disease (damage to the small blood vessels), which could ultimately lead to more serious complications.

12 Jul 2024

Four years non-diabetic status after impaired glucose tolerance diagnosis cuts cardiovascular risks

Maintaining non-diabetic status for at least four years after impaired glucose tolerance diagnosis significantly lowers the risk of cardiovascular complications and mortality.

10 Jul 2024

Genetic variation in people of African ancestry linked to increased risk of diabetes complications

A genetic variation common in people of African ancestry is associated with an increased risk of complications from diabetes, including diabetic retinopathy, according to a report published June 25 in the journal Nature Medicine.

25 Jun 2024

Study reveals critical role of ADGRF5 in maintaining glomerular filtration barrier integrity

Glomerulus, the fundamental filtering unit of the kidney, is an intricate network of capillaries - small blood vessels that regulate the movement of ions, water, and metabolites while maintaining impermeability to essential macromolecules such as proteins.

21 Jun 2024

Hybrid technique identifies anti-nephrin autoantibodies as biomarker for kidney disorders with nephrotic syndrome

A groundbreaking study, presented today at the 61st ERA Congress, has uncovered a significant breakthrough in the diagnosis and monitoring of kidney diseases associated with nephrotic syndrome.

25 May 2024

Study identifies strong link between red, processed meat intake and severe kidney damage in diabetic women

The link between red, processed, and white meat consumption and the likelihood of developing kidney damage and diabetic nephropathy.

8 May 2024

Cinnamon, curcumin, and resveratrol show promise in diabetes inflammation fight

Researchers reviewed the impact of cinnamon, curcumin, and resveratrol on oxidative stress and inflammation in type 2 diabetes patients, highlighting their potential to improve metabolic regulation and reduce complications.

26 Apr 2024

Researchers find new clues to understanding the progression of primary membranous nephropathy

No therapies currently exist that can halt the progression of chronic kidney disease in children or restore the ability of kidney cells to filter blood.

9 Apr 2024

Long-term study shows struggle with weight loss in newly diagnosed type 2 diabetics

A register-based study from Finland identified three distinct BMI trajectory groups among patients with newly diagnosed type 2 diabetes. In a four-year follow-up, most patients followed a stable trajectory without much weight change.

4 Apr 2024

Mapping the genomic landscape of Type 2 diabetes

In the largest genome-wide association study to date on Type 2 diabetes, a team of international researchers, co-led by a University of Massachusetts Amherst genetic epidemiologist, has located 1,289 genetic markers associated with Type 2 diabetes (145 of which are newly identified) and generated risk scores for diabetes complications.

19 Feb 2024

6th CKD Drug Development Summit: Countdown Begins

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From 6th CKD Drug Development Summit 16 Feb 2024

Review of traditional treatments and novel nutritional interventions for sickle cell disease

Nutrition-related studies involving sickle cell disease (SCD) patients, particularly those in Africa.

17 Jan 2024