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Technological roadmap proposed for lifetime brain-wide neural recordings

Understanding the brain requires tools that can follow neural activity across many scales: from millisecond electrical spikes in individual neurons to brain-wide circuit dynamics that change over months, years, and even a lifetime.

9 Sep 2026

Deep sleep brain activity helps mice resist social stress

Most adult sleep is non-rapid eye movement (REM), which is restorative and promotes resilience to stressful conditions. However, the brain mechanisms for non-REM sleep's relationship to stress resilience remain unclear.

7 Sep 2026

Inhibitory neurons act as a brake on brain tumor growth

Brain tumors do not grow in isolation. They develop within the highly active environment of the brain, where neurons continuously exchange electrical and chemical signals.

7 Sep 2026

Younger and older brains respond differently to traumatic injury

Conventional wisdom holds that younger brains are better equipped to recover from injury. Their greater flexibility allows them to adapt, rebuild connections and compensate for damage in ways older brains often cannot.

4 Sep 2026

What your genes can, and cannot, tell us about your personality

A meta-analysis of 46 cohorts involving 611,037 to 1.14 million participants identified 1,260 lead genetic variants associated with the Big Five personality traits, including 824 in previously unlinked genomic regions. The associations were broadly consistent across cohorts and measurement contexts, while polygenic analyses linked personality-related genetics to health, behavior, psychopathology, and life outcomes, although effects were modest and could not predict individual behavior.

3 Sep 2026

Neural networks reveal how training shapes learning in living brains

A new study has used a type of machine learning called a neural network to reveal how different kinds of training can change how learning happens-both in machines, and in living brains.

3 Sep 2026

Maternal illness may reshape fetal brain development through epigenetics

Neurodevelopmental conditions, which include autism spectrum disorders, ADHD (attention-deficit/hyperactivity disorder), and more, impact around ten percent of the American population.

2 Sep 2026

New brain atlas reveals insights into Huntington's, addiction, and other disorders

A region of the brain called the striatum is critical for many cognitive and motor functions, including decision-making, control of movement, habit formation, and processing of reward.

1 Sep 2026

Salk researchers isolate specific neurons controlling complex social behaviors

Our brains constantly integrate information about both our internal state and our surroundings to determine how we behave.

27 Aug 2026

Nanoparticles regenerate neurons and improve cognition in Alzheimer’s mice

The adult human brain has limited capacity to repair or regenerate neurons lost to Alzheimer's disease, the most common type of dementia.

26 Aug 2026

Oxford study identifies brain mechanisms behind our sense of control

A study led by the University of Oxford has identified the brain mechanisms that help us work out whether the consequences we experience are caused by our own actions or by circumstances beyond our control.

21 Aug 2026

Glioma microenvironment emerges as key target for future therapies

The prognosis for glioma patients remains extremely poor despite aggressive multimodal standard therapy: maximal safe resection, radiotherapy, and temozolomide chemotherapy, with median survival rarely exceeding 15 to 18 months.

20 Aug 2026

Researchers maintain brain organoids for longer than ever before

An international team of researchers has maintained brain organoids, three-dimensional models of human brain tissue, for longer than ever before.

20 Aug 2026

A single blood test could offer a glimpse of disease risk years in advance

Machine learning-derived cellular aging clocks mapped more than 7,000 plasma proteins to over 40 cell types, revealing marked differences in how individual cell populations age. These blood-based signatures were associated with future risks of Alzheimer’s disease, ALS, lung cancer, type 2 diabetes, and mortality across follow-up extending to 15 years.

19 Aug 2026

New microscope tracks electrical activity across the brain on the scale of milliseconds

Within the brain, neurons compute by generating electrical impulses. These signals travel throughout neurons, which are in turn connected in vast networks that control brain functions such as sensory perception, memory formation, and control of movement.

14 Aug 2026

Astrocytes found to directly regulate memory consolidation during sleep

Research has shown that a good night's sleep has many benefits, including memory consolidation. How sleep enables the brain to strengthen memories is still not completely understood, but a new study published in Neuron reveals how astrocytes, brain cells known for supporting neurons and their functions, can directly regulate brain circuits involved in memory consolidation.

13 Aug 2026

Mitochondrial protein deficiency drives increased fat intake and obesity

Obesity is a global health concern that can contribute to diabetes, cardiovascular disease, and other metabolic disorders.

13 Aug 2026

Brain scans reveal language-specific network of neurons even during nonlinguistic tasks

The language network in your brain can be seen, even if you aren't saying a word.

13 Aug 2026

High frequency brain waves help coordinate human working memory

Research from scientists at University of California San Diego School of Medicine and collaborators has shed new light on how the human brain coordinates working memory, the process in which the brain encodes information for immediate or short-term use.

12 Aug 2026

Targeting single gene reverses developmental deficits in adult mice

Some of the symptoms of neurodevelopmental disorders (NDDs) such as autism spectrum disorder and epilepsy may result from dysfunction of certain neurons in the brain and their ability to change their properties in response to experiences-a process called experience-dependent plasticity.

12 Aug 2026