Oral Cancer News and Research

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Oral cancer is the sixth most common type of cancer worldwide and in the U.S., one person dies every hour from the disease. According to American Cancer Society data, nearly as many women will be diagnosed with oral cancer as with cervical cancer this year. The key to reducing the impact of this disease is early detection.

A large-scale tongue cancer organoid library for precision oncology

Oral cancer is an increasingly prevalent disease worldwide, with over 300,000 new cases diagnosed each year. Among oral cancers, tongue cancer (TC) is the most common type and often carries a poor prognosis. Surgery combined with chemoradiotherapy is one of the main lines of treatment for high-risk cases of TC.

9 Jan 2025

A roadmap for improving cancer care in South Asia

A series of five papers, published today in The Lancet Oncology by a University of Pittsburgh-led international team, highlights critical public health challenges related to cancer control in the eight countries that form the South Asian Association for Regional Cooperation (SAARC) and the Rohingya refugee population in Bangladesh.

3 Dec 2024

WHO hosts historic meeting to address global oral health challenges

Delegations from over 110 countries are coming together to produce national roadmaps and negotiate a joint declaration on oral health at the first-ever global oral health meeting organized by the World Health Organization (WHO).

26 Nov 2024

Curcumin shows promise in preventing and treating oral submucosal fibrosis

Researchers explore the mechanisms, therapeutic potential, and clinical applications of curcumin in preventing and treating oral submucosal fibrosis.

30 Oct 2024

NIH supports research on non-opioid pain relief for oral cancer patients

The School of Dentistry at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) earned the first National Institutes of Health grant under its new Center for Pain Therapeutics and Addiction Research, addressing pain in patients with head and neck carcinoma.

4 Oct 2024

Researchers discover how oral cancer cells may block the body's immune response

Macquarie University researchers have discovered new information about how oral cancer cells may block the body's immune response. This could lead to better treatments for this aggressive disease.

18 Sep 2024

Interdisciplinary team reveals how Porphyromonas gingivalis interferes with chemotherapy-induced mitophagy

A new paper from an interdisciplinary team at MUSC Hollings Cancer Center describes how the bacteria Porphyromonas gingivalis interferes with chemotherapy-induced mitophagy, allowing oral cancer tumors to become resistant to the drug's effects.

18 Jun 2024

Foam technology revolutionizes gene therapy, boosting efficiency and safety

Liquid foam gene delivery significantly enhances transfection efficiency and safety, offering a cost-effective alternative to conventional methods.

3 Jun 2024

Mayo Clinic researchers uncover microbial signatures linked to gynecologic cancers

Early detection improves treatment outcomes for endometrial and ovarian cancers, yet far too often women are diagnosed in advanced stages of these diseases.

30 May 2024

Physician-pharmacy integration not associated with change in the care of cancer patients

Integration of pharmacies with physician practices, where on-site pharmacies open at physician practice locations, is a growing trend in cancer treatment.

23 May 2024

New insights into Chaga mushroom's mechanisms for fighting oral cancer

The mechanisms behind the anti-tumor activity of Chaga mushroom extracts in HSC-4 human oral cancer cells.

13 May 2024

Developing mRNA lipid nanoparticles for treating oral squamous cell carcinoma

A study aiming to develop a Lipid nanoparticles (LNP) platform for treating oral squamous cell carcinoma (OSCC) utilizing p53 mRNA was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of the American Association for Dental, Oral, and Craniofacial Research and the 48th Annual Meeting of the Canadian Association for Dental Research, on March 13-16, 2024, in New Orleans, LA, USA.

19 Mar 2024

Researchers discover a noninvasive, low-cost test to detect oral cancer

Oral cancers and precancerous mouth lesions are considered especially difficult to diagnose early and accurately.

4 Mar 2024

Study shines light on partial endothelial-to-mesenchymal transition in the tumor microenvironment

Endothelial-mesenchymal transition (EndoMT, also termed as EndMT), a biological process resulting in the formation of mesenchymal (or lineage-committed) phenotypes from endothelial cells (lining blood vessels), plays a crucial role in tumor progression.

7 Feb 2024

The crucial need for ongoing COVID-19 booster vaccination in vulnerable populations

Researchers investigate the need for prioritizing COVID-19 booster vaccination.

19 Jan 2024

New brush test outperforms biopsies in early oral cancer detection

A new test invented by University of Illinois Chicago researchers allows dentists to screen for the most common form of oral cancer with a simple and familiar tool: the brush.

17 Jan 2024

"Healthy Smiles, Healthy Hearts" initiative bridges oral health and heart health

A patient's oral health can be an indicator of overall health and well-being. Research shows that chronic gum inflammation may be associated with other chronic diseases including coronary artery disease and diabetes.

16 Jan 2024

Does inflammatory bowel disease have a causal relationship with extracolonic tumors?

Whether inflammatory bowel disease (IBD) is causally related to extracolonic cancers.

17 Oct 2023

Saliva test breakthrough: Early detection for ectopic pregnancies on the horizon

Salivary proteins may offer early detection for ectopic pregnancies, potentially saving maternal lives through a non-invasive diagnostic approach. The study identifies specific proteins that are prominently present in ruptured ectopic pregnancy cases, highlighting the potential for developing a saliva-based diagnostic kit.

9 Oct 2023

What's really in your mouthwash? Turkish study spills the minty truth

Researchers review the ingredients and potential health impacts of commercially available mouthwashes in Turkey, revealing a mix of beneficial and potentially harmful components. The study highlights the need for further research on the health effects of mouthwash ingredients, especially given the high incidence of dental disorders in Turkey.

17 Sep 2023