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Study shows reduced bleeding risk with ticagrelor monotherapy after percutaneous coronary intervention

People who have had a heart attack or who are at risk for a heart attack and who stopped taking aspirin alongside the P2Y12 inhibitor ticagrelor one month after undergoing percutaneous coronary intervention (PCI) saw a significantly reduced risk of clinically meaningful bleeding with no increased risk of clotting-related adverse events at 12 months compared with patients who continued taking aspirin and ticagrelor for a full year, in a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Investigational drug plozasiran shows promise in reducing severe hypertriglyceridemia

In patients with severely elevated triglyceride levels at risk for developing acute pancreatitis, the investigational drug plozasiran reduced triglyceride levels by an average of 74% after 24 weeks of use without causing any significant safety concerns, according to research presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Ten doctors on FDA panel reviewing Abbott heart device had financial ties with company

When the FDA recently convened a committee of advisers to assess a cardiac device made by Abbott, the agency didn't disclose that most of them had received payments from the company or conducted research it had funded — information readily available in a federal database.

8 Apr 2024

Study shows promise of zilebesiran injection in reducing systolic blood pressure

A single subcutaneous injection of the investigational drug zilebesiran, when added to existing treatment with a standard antihypertensive medication, reduced systolic blood pressure by between 4 to 12 mmHg on average at three months in patients whose blood pressure had remained uncontrolled despite compliance with their medication regimen, according to a study presented at the American College of Cardiology's Annual Scientific Session.

7 Apr 2024

Biden is right about $35 insulin cap but exaggerates prior costs for Medicare enrollees

The cost of insulin in the United States has risen considerably in recent years, with some estimates finding that Americans have paid around 10 times as much for the drug as people in other developed countries.

5 Apr 2024

Adeno-associated virus: The gene therapy revolution faces manufacturing and safety hurdles

Recombinant adeno-associated virus (rAAV)-based genetic applications to treat human diseases.

5 Apr 2024

Lancet Commission predicts sharp increase in global prostate cancer cases

Cases of prostate cancer are projected to double from 1.4 million per year in 2020 to 2.9 million per year by 2040, with low- and middle-income countries (LMICs) predicted to see the highest increases in cases, according to The Lancet Commission on prostate cancer which will be launched by a presentation at the European Association of Urology Congress.

4 Apr 2024

Gene therapy and glycoside drugs offer new hope for polycystic kidney disease treatment

Researchers have shown that dangerous cysts, which form over time in polycystic kidney disease (PKD), can be prevented by a single normal copy of a defective gene.

4 Apr 2024

Researchers discover a safer and more efficient technique for testing new drugs

McGill researchers have discovered a safer and more efficient technique for testing new drugs while they are in development.

28 Mar 2024

KFF Health News' 'What the Health?': The Supreme Court and the abortion pill

In its first abortion case since the overturning of Roe v. Wade in 2022, the Supreme Court this week looked unlikely to uphold an appeals court ruling that would dramatically restrict the availability of the abortion pill mifepristone.

28 Mar 2024

At stake in mifepristone case: Abortion, FDA’s authority, and return to 1873 obscenity law

Lawyers from the conservative Christian group that won the case to overturn Roe v. Wade are returning to the U.S. Supreme Court on Tuesday in pursuit of an urgent priority: shutting down access to abortion pills for women across the country.

25 Mar 2024

A paramedic was skeptical about this Rx for stopping repeat opioid overdoses. Then he saw it help.

Fire Capt. Jesse Blaire steered his SUV through the mobile home park until he spotted the little beige house with white trim and radioed to let dispatchers know he'd arrived.

25 Mar 2024

Study highlights global fertility decline and its implications for the future

The world is approaching a low-fertility future. Although by 2100 more than 97% of countries and territories will have fertility rates below what is necessary to sustain population size over time, comparatively high fertility rates in numerous low-income countries, predominantly in western and eastern sub-Saharan Africa, will continue to drive population increases in these locations throughout the century.

21 Mar 2024

KFF Health News' 'What the Health?': The ACA turns 14

The Affordable Care Act was signed into law 14 years ago this week, and Health and Human Services Secretary Xavier Becerra joined KFF Health News' Julie Rovner on this week's "What the Health?" podcast to discuss its accomplishments so far — and the challenges that remain for the health law.

21 Mar 2024

Pembrolizumab enhances breast cancer treatment regardless of age or menopausal status

New data from the KEYNOTE-756 phase 3 clinical trial show that adding the immunotherapy drug, pembrolizumab, to chemotherapy before and after surgery for breast cancer leads to better outcomes for patients regardless of their age or menopausal status.

20 Mar 2024

Watch: Many Americans are unaware of HIV prevention medication

Céline Gounder, KFF Health News' editor-at-large for public health, explained on "CBS Mornings" why many at-risk Americans do not know about medication to prevent HIV infection through sexual contact or do not have access to it.

20 Mar 2024

Antipsychotic use during pregnancy not linked to childhood neurodevelopmental disorders or learning difficulties

The use of antipsychotics during pregnancy isn't linked to childhood neurodevelopmental disorders or learning difficulties, UNSW Sydney-led study shows – giving assurance to those concerned about continuing their medications during pregnancy.

18 Mar 2024

New compounds show potential to mimic benefits of exercise

Doctors have long prescribed exercise to improve and protect health. In the future, a pill may offer some of the same benefits as exercise.

18 Mar 2024

Novel scoring system can distinguish between two serious skin diseases

Your skin becomes red and spots filled with pus appear, so you visit a dermatologist. When these symptoms spread to the skin throughout the body, it is difficult for the physician to distinguish whether it is generalized pustular psoriasis (GPP) or acute generalized exanthematous pustulosis (AGEP), as both have similar symptoms.

18 Mar 2024

Innovative levodopa infusion pump trial shows promise for reducing Parkinson's symptoms

An international, multisite phase 3 trial co-led by a University of Cincinnati researcher found Parkinson's disease medication delivered through an infusion pump is safe and effective at reducing symptoms for longer periods of time.

15 Mar 2024

Pharmaceuticals News and Research

Study shows reduced bleeding risk with ticagrelor monotherapy after percutaneous coronary intervention

Investigational drug plozasiran shows promise in reducing severe hypertriglyceridemia

Ten doctors on FDA panel reviewing Abbott heart device had financial ties with company

Study shows promise of zilebesiran injection in reducing systolic blood pressure

Biden is right about $35 insulin cap but exaggerates prior costs for Medicare enrollees

Adeno-associated virus: The gene therapy revolution faces manufacturing and safety hurdles

Lancet Commission predicts sharp increase in global prostate cancer cases

Gene therapy and glycoside drugs offer new hope for polycystic kidney disease treatment

Researchers discover a safer and more efficient technique for testing new drugs

KFF Health News' 'What the Health?': The Supreme Court and the abortion pill

At stake in mifepristone case: Abortion, FDA’s authority, and return to 1873 obscenity law

A paramedic was skeptical about this Rx for stopping repeat opioid overdoses. Then he saw it help.

Study highlights global fertility decline and its implications for the future

KFF Health News' 'What the Health?': The ACA turns 14

Pembrolizumab enhances breast cancer treatment regardless of age or menopausal status

Watch: Many Americans are unaware of HIV prevention medication

Antipsychotic use during pregnancy not linked to childhood neurodevelopmental disorders or learning difficulties

New compounds show potential to mimic benefits of exercise

Novel scoring system can distinguish between two serious skin diseases

Innovative levodopa infusion pump trial shows promise for reducing Parkinson's symptoms

Pittcon Highlights: Pharmaceutical & Biologic eBook

Changing the landscape of R&D to build clinical success from the ground up

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

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