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New study identifies key pathway for delivering antisense cancer drugs

Antisense oligonucleotides (ASOs) have been proposed as a therapeutic approach to shut down the production of faulty proteins in a wide variety of diseases, including cancer.

11 Aug 2026

Restricting select amino acids may mimic protein restriction’s healthy aging benefits

A review finds that restricting protein, particularly methionine, isoleucine, and valine, may improve metabolism and influence key aging pathways, largely in experimental models. Short human studies suggest metabolic benefits, but effects on lifespan remain unknown and restriction may harm people with unmet or increased protein needs.

3 Aug 2026

Researchers propose new framework to define clinical obesity

A new approach to defining obesity could help physicians better determine which patients need more intensive treatment by focusing on the effects of excess adiposity on organs and tissues rather than relying primarily on whether a person meets a set of metabolic risk thresholds.

31 Jul 2026

Soy lysolecithin reduces salt-induced hypertension and cognitive decline

High salt (HS) intake is a major global health concern, closely linked to hypertension and growing evidence of cognitive and emotional decline.

31 Jul 2026

New chemical method breaks rules to speed up drug discovery

Binghamton University chemists have discovered a new mechanism that could potentially lead to quicker outcomes in pharmaceutical research.

30 Jul 2026

Researchers identify key barrier preventing self repair of heart cells

Specialized cells in our body make biological tradeoffs to do certain jobs. To support large and hardworking hearts that power our other organs, our heart cells evolved to be extremely efficient and resilient.

28 Jul 2026

Advancing Drug Safety Assessment With AI, Predictive Modeling, and Human-Relevant Data

James McDonagh discusses how AI and machine learning are transforming drug discovery and safety assessment, enhancing toxicology and decision-making processes.

27 Jul 2026

Inherited genetics can influence safety and success of CAR-T cell therapy

Chimeric antigen receptor (CAR)-T cell therapy, which reprograms an individual's immune cells to seek out and destroy certain cancer cells, has revolutionized treatment for blood cancers such as lymphoma.

24 Jul 2026

Tailored gene therapy dramatically reduces childhood epilepsy seizures in trial

SCN2A‑related developmental epileptic encephalopathy (DEE) is a rare, severe form of childhood epilepsy and one of the most common causes of monogenic autism.

21 Jul 2026

Study examines the link between blood type and cardiovascular risk in hemodialysis patients

Do you know your blood type? It is important information that is used for blood transfusions, but few realize blood types could also be linked to disease risks. In the general population, people with blood type O have been reported to have a lower risk of cardiovascular disease and cardiovascular mortality.

21 Jul 2026

Daily polypill significantly improves cardiac function in heart failure patients

Treatment with a "polypill" that combines multiple medications into a single daily dose significantly enhanced cardiac function and reduced hospitalizations for patients with heart failure, according to a study led by Michigan Medicine and UT Southwestern Medical Center.

20 Jul 2026

Popular diabetes drugs do not alter the risk of developing a blinding eye condition

An estimated 27% of U.S. adults with diabetes are using glucagon-like peptide-1 receptor agonists (GLP-1 RAs) - a type of medication that mimics the GLP-1 hormone - to lower blood sugar and support weight loss. Some research has suggested that their use can reduce the risk of developing other diseases.

17 Jul 2026

Experimental KRAS vaccine safely generates durable immune response against pancreatic cancer

Researchers at the Johns Hopkins Kimmel Cancer Center and its Skip Viragh Center for Pancreatic Cancer report that an experimental vaccine targeting mutant KRAS, one of the most common genetic drivers of pancreatic cancer, was safe and generated durable immune responses aimed at preventing the cancer in people at high risk.

16 Jul 2026

Europe’s fragmented early access landscape intensifies need for operational strategy ahead of the 5th Operationalise: Early Access Programmes Summit Europe

Join industry leaders at the 2026 summit to discuss strategies for navigating early access programmes and improving patient access to investigational therapies.

From 5th Operationalise: Early Access Programmes Summit Europe 15 Jul 2026

Insilico and Bora Pharmaceuticals forge strategic AI-driven drug discovery alliance

Insilico Medicine, a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, today announced a multi-target strategic alliance with Bora Pharmaceuticals Co., Ltd., a global leader in pharmaceutical manufacturing.

14 Jul 2026

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

Frances Arnold on directed enzyme evolution: random mutation plus smart screening, and why it changed enzyme engineering and industry.

From Pittcon 14 Jul 2026

AI could accelerate commercialization of bio-based chemical manufacturing

The era of "biomanufacturing", in which microbes, not petroleum, produce chemical products, is one step closer. A KAIST research team has analyzed the key challenges limiting the commercialization of biomanufacturing and proposed an AI-driven strategy for industrialization.

13 Jul 2026

Phelan-McDermid syndrome may be more common than previously believed

New research, led by scientists from the Seaver Autism Center for Research and Treatment at Mount Sinai and published June 28 in Autism Research, has estimated that Phelan-McDermid syndrome (PMS) affects approximately 1 in 7,300 people, making it dramatically more common than previous estimates suggested.

9 Jul 2026

Setmelanotide shows promise for hypothalamic obesity after brain tumors

A new therapy helps achieve a healthier BMI in people whose weight has become dysregulated following treatment for a brain tumor, a clinical trial has found.

8 Jul 2026

Socioeconomic status brings unequal metabolic disease reductions across racial, ethnic groups

Higher socioeconomic status is not associated with equal reductions in rates of type 2 diabetes and obesity across all racial and ethnic groups in the United States, according to a new study published July 8, 2026, in the open access journal PLOS One by Sara Cromer of Harvard Medical School, USA, and colleagues.