RNA Sequencing News and Research

RSS

Researchers traced lifelong obesity resistance in mice back to an early microbial encounter

Natural wild-derived microbiota protected mice against diet-induced obesity across sexes, genetic backgrounds, and age by increasing energy expenditure and promoting a thermogenic program in brown adipose tissue. The effect depended on the immune system’s initial encounter with the microbiota and required CCR2-associated myeloid activity, revealing a long-lasting microbiota-immune-brown fat pathway.

25 Aug 2026

New study makes progress in understanding the mechanisms behind severity of HFpEF

Approximately 3 million people in the United States are living with a condition called heart failure with preserved ejection fraction, or HFpEF.

24 Aug 2026

Bonsai software visualizes complex biological data as branching trees

Modern biology research can now generate valuable data on an unprecedented scale. But there is one major obstacle: making sense of these complex high-dimensional datasets.

21 Aug 2026

New study links chronic stress to immunotherapy resistance in tumors

Immunotherapy has transformed cancer treatment, yet many tumors remain stubbornly resistant to its effects.

18 Aug 2026

Study provides new insights into how IL-26 reshapes the tumor immune landscape

While cancer cells acquire malignant traits through epigenetic remodeling, it remains unclear how immune-derived inflammatory factors regulate the epigenetics of colorectal cancer cells.

18 Aug 2026

Computational pipeline uncovers subtype specific targets for cervical cancer

A new study presents a multi-layered strategy for identifying cell-surface targets that could help guide more precise antibody-drug conjugate (ADC) development for cervical cancer, with different targets showing distinct potential across tumor subtypes.

17 Aug 2026

Engineered immune cells help eliminate severe bacterial infections effectively

Severe bacterial infections remain a major global health challenge because antibiotics alone often fail when the host immune system becomes dysfunctional.

17 Aug 2026

Polydatin reduces ulcerative colitis by regulating intestinal immune cells

Ulcerative colitis (UC) is a chronic inflammatory bowel disease in which recurrent intestinal inflammation can be difficult to control over the long term.

17 Aug 2026

$Muscle cells play a vital role in repairing fractured bones$

Muscle cells play a vital role in repairing fractured bones

Bone healing is a complex process that depends on the coordinated activity of many different cell types.

14 Aug 2026

New study challenges long-held view of common bacterial resident of the lungs

Our bodies are teeming with more than 35 trillion bacteria, coexisting in microbiomes inside our guts, mouths, lungs, skin and urogenital tract.

13 Aug 2026

Aging clock analysis identifies key genes in opioid dependence

A new research paper was published in Volume 18 of Aging on July 27, 2026, titled "Transcriptomic aging clock analysis identifies key genes in opioid dependence."

12 Aug 2026

Early-life stress rewires brain epigenetics to heighten sensitivity to future stress

. Early-life stress increased SETD7 and H3K4me1 in the ventral tegmental area of mice, creating an epigenetically primed state that heightened later transcriptional, neuronal, and behavioral responses to stress. Reducing Setd7 during development lowered H3K4me1 and weakened these stress-sensitizing effects, identifying a mechanism that may help explain how early adversity leaves lasting biological effects.

11 Aug 2026

Study identifies key immune cell changes in the lungs of people with sarcoidosis

Researchers at National Jewish Health and partner institutions discovered specific changes in immune cells in the lungs of people with sarcoidosis.

10 Aug 2026

Severe COVID-19 reactivates dormant viruses and may leave a lasting viral signature

A longitudinal study of 1,154 hospitalized COVID-19 patients found widespread reactivation of chronic Herpesviridae and Anelloviridae, with distinct viral patterns linked to disease severity, inflammation, and clinical outcomes. Anelloviridae also persisted during convalescence and were associated with physical deficits in long COVID, although the study did not establish causation.

7 Aug 2026

International team builds comprehensive cancer models for future drug development

To develop new targeted treatments for cancer, scientists need tissue models that accurately represent the genetic and molecular traits of the cancer they're studying.

5 Aug 2026

Nerve-blocking therapy improves growth plate repair in injured bones

With the support of National Institutes of Health funding, Johns Hopkins Medicine investigators, led by pathologist Aaron W. James, M.D., Ph.D., previously discovered that sensory neurons in skeletal tissue are constantly sensing their environment and are quick to respond to injuries.

5 Aug 2026

RNA Sequencing News and Research

Researchers traced lifelong obesity resistance in mice back to an early microbial encounter

New study makes progress in understanding the mechanisms behind severity of HFpEF

Bonsai software visualizes complex biological data as branching trees

New study links chronic stress to immunotherapy resistance in tumors

Study provides new insights into how IL-26 reshapes the tumor immune landscape

Computational pipeline uncovers subtype specific targets for cervical cancer

Engineered immune cells help eliminate severe bacterial infections effectively

Polydatin reduces ulcerative colitis by regulating intestinal immune cells

Muscle cells play a vital role in repairing fractured bones

New study challenges long-held view of common bacterial resident of the lungs

Aging clock analysis identifies key genes in opioid dependence

Early-life stress rewires brain epigenetics to heighten sensitivity to future stress

Study identifies key immune cell changes in the lungs of people with sarcoidosis

Severe COVID-19 reactivates dormant viruses and may leave a lasting viral signature

International team builds comprehensive cancer models for future drug development

Nerve-blocking therapy improves growth plate repair in injured bones

Insilico Medicine highlights AI-powered biological target discovery for rare sinonasal cancer

Ketamine boosts neuroplasticity through microglia in female brains

Scientists map protective cell networks hiding dormant breast tumor cells

Accumulation of somatic mutations drives vascular damage in people with progeria

Sequencing & Genomics: Elevating Science and Healthcare eBook

Latest eBooks

New horizons in drug discovery: High-throughput & target-to-therapy advances

A practical guide to lipid nanoparticle formulation and resizing

Editorial Focus eBook - Spatial and single-cell omics (1st edition)

Industry Focus eBook - Analytical Chemistry (3rd edition)

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology