Septic Shock News and Research

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New study reveals key blood markers for sepsis diagnosis in burn patients

The efficacy of Complete Blood Count (CBC) parameters in diagnosing sepsis.

10 Jan 2024

Three cytokine pairs found to be responsible for the body's damaging response to sepsis

Sepsis - when an infection causes the immune system to improperly target the body - is one of the leading causes of death in the ICU.

8 Jan 2024

Phase I clinical trial of new CAR T cell therapy AT101 shows promising early responses

Early results from a Phase I clinical trial of AT101, a new CAR T cell therapy that uses a distinct binding mechanism to target CD19, show a 100 percent complete response (CR) rate at the higher dose levels studied in the trial, according to researchers from the University of Pennsylvania Perelman School of Medicine and Penn Medicine's Abramson Cancer Center.

11 Dec 2023

BMI should not be used to determine eligibility for gender-affirming chest surgery

Body mass index, or BMI, is a person's mass (weight) in kilograms divided by the square of their height in meters.

7 Nov 2023

Is there an association between vitamin D deficiency and sepsis mortality?

The impact of deficient serum vitamin D levels on sepsis prognosis.

12 Oct 2023

Feds hope to cut sepsis deaths by hitching Medicare payments to treatment stats

Don Smith remembers the moment he awoke in an intensive care unit after 13 days in a medically induced coma. His wife and daughter were at his bedside, and he thought it had been only a day since he arrived at the emergency room with foot pain.

11 Oct 2023

Patients with heart conditions should practice good hygiene to prevent infective endocarditis

Patients with specific cardiac conditions such as valvular heart disease and congenital abnormalities, or those requiring a pacemaker, should practice good dental and skin hygiene to help prevent rare but potentially deadly infections of the heart's inner lining and valves, according to European Society of Cardiology (ESC) Guidelines on infective endocarditis, published online today in European Heart Journal.

25 Aug 2023

STING gene variant linked to increased risk of severe group A strep infections

Group A streptococci are fairly common bacteria that can cause, among other things, strep throat or impetigo.

17 Aug 2023

Role of M2 macrophage-derived exosomes in controlling neutrophil-mediated tissue injury in sepsis

Researchers investigate whether M2 macrophage-derived exosomes could prevent inflammation-associated damage during sepsis.

7 Aug 2023

Study reports the first protein-based diagnostic signature to discriminate MIS-C from Kawasaki Disease and other common infections

Researchers explore the distinguishing features of MIS-C as compared to other inflammatory-infectious syndromes in children.

4 Aug 2023

Study shows that COVID-19 patients presented different plasma trace elements levels depending on disease severity

Lower blood levels of certain trace elements are associated with critical COVID-19 outcomes.

31 Jul 2023

COVID-19 treatment: study evaluates ACEi and ARB effects on clinical outcomes

A group of researchers compared the effects of angiotensin-converting enzyme inhibitors (ACEi) and angiotensin II receptor blockers.

27 Jul 2023

Will a ‘national patient safety board,’ modeled after the NTSB, actually fly?

People concerned about the safety of patients often compare health care to aviation. Why, they ask, can't hospitals learn from medical errors the way airlines learn from plane crashes?

5 Jun 2023

The clinical and virological characteristics of severe neonatal echovirus 11 infections

Researchers described severe and fatal infections in neonates caused by a new echovirus 11 (E-11) variant in France.

5 Jun 2023

Combination therapy successfully treats Pasteurella multocida-related invasive infections

Announcing a new article publication for Zoonoses journal. Pasteurella multocida, a Gram-negative, penicillin-sensitive coccobacillus that is frequently a member of the normal respiratory microbiota of different animals, remains a clinically important pathogen with the ability to cause severe disease. Few case reports have involved P. multocida infections without animal bites.

4 Jun 2023

Study examines the role of hydrocortisone in the management of adult patients with septic shock

Sepsis is a global health priority affecting 55 million patients worldwide and causing 11 million deaths annually. Treatment for sepsis may include prompt recognition, source control, antibiotics, fluids, vasopressors, and adjunctive therapies.

22 May 2023

Study finds biomarker pattern in children with COVID 19-linked multisystem inflammatory syndrome

Children with multisystem inflammatory syndrome (MIS-C) — a rare condition linked with the virus that causes COVID-19 — have biochemical indicators of cell injury and cell death that are distinct from other children with COVID-19, according to a study funded by the National Institutes of Health.

25 Apr 2023

Combination of hydrocortisone and fludrocortisone benefits patients with septic shock

Sepsis occurs in approximately 1.7 million hospitalizations in the U.S. with in more than a third of hospitalizations resulting in death.

27 Mar 2023

mNGS outperforms microbiological tests to diagnose bloodstream infections – BGI Insight

Next-generation sequencing (mNGS) leverages genetic testing advantage to save more lives; twice as effective at identifying infection cases.

From BGI Genomics 24 Mar 2023

Study highlights the emergence of S. cerevisiae as an opportunistic fungal pathogen in immunosuppressed patients presenting several severe comorbidities

Researchers from Brazil presented a fatal case of a patient developing Saccharomyces cerevisiae infection and succumbing to septic shock after contracting and recovering from a SARS-CoV-2 infection.

7 Feb 2023