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Oral relaxin agonist AZD5462 improves cardiac function in heart failure patients

The oral relaxin agonist, AZD5462, improved cardiac function in patients with chronic heart failure, according to results presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in Circulation.

30 Aug 2026

People with diabetes may have another reason to protect their cardiovascular health

Better cardiovascular health, measured using Life’s Essential 8, was associated with a lower risk of mild cognitive impairment among people with diabetes after accounting for genetic susceptibility. Associations with dementia varied by genetic risk, while higher LE8 scores were also linked to greater gray matter volume and lower white matter hyperintensity volume.

30 Aug 2026

REACT study maps widespread silent atherosclerosis across adult lifespan

Silent atherosclerosis was detectable from early adulthood and showed sex-specific patterns of growth with age, according to results from the REACT study presented in a Hot Line session today at ESC Congress 2026 and published simultaneously in the New England Journal of Medicine.

29 Aug 2026

Investigational anti-interleukin-6 monoclonal antibody achieves durable inflammatory biomarker reductions

The investigational anti-interleukin-6 (IL-6) monoclonal antibody pacibekitug produced sustained reductions in inflammation-related biomarkers through six months in patients with chronic kidney disease and elevated inflammatory risk associated with heart disease.

29 Aug 2026

New study detects silent atherosclerosis in healthy young adults

Atherosclerosis, the process underlying most cardiovascular diseases, begins long before the first symptoms appear.

29 Aug 2026

Specialized blood vessel cells found to actively drive lung fibrosis

Millions of people worldwide are affected by diseases that cause scarring of the lungs, often leading to breathing difficulties and reduced quality of life.

28 Aug 2026

Molecular switch ERBB4 linked to broad range of Alzheimer's pathologies

What if amyloid plaques are not the whole story of Alzheimer's disease? New research suggests that a broad range of Alzheimer's pathologies may be orchestrated by a molecular switch called ERBB4 when it turns on in the wrong neurons.

26 Aug 2026

Vagus nerve stimulation may enhance long-term motor learning

Do you ever feel like sometimes you can master a new dance step almost immediately, while other times you struggle to nail it despite repeated practice? This might be due to skill or effort, but also to something less obvious: whether the brain is in a state that allows learning to take hold.

26 Aug 2026

New artificial lung mimics breathing and alveolar movement

Almost everyone has blown a soap bubble through a straw at least once. Inspired by this thin soap bubble film, an "artificial lung that breathes" like a real lung has been developed.

25 Aug 2026

Mitochondrial transplantation helps repair donor organs during machine perfusion

Transplant medicine still depends on a limited supply of donor organs, while many retrieved grafts are discarded because ischemia, cold storage, and reperfusion can rapidly damage their cells.

25 Aug 2026

New study makes progress in understanding the mechanisms behind severity of HFpEF

Approximately 3 million people in the United States are living with a condition called heart failure with preserved ejection fraction, or HFpEF.

24 Aug 2026

Disrupted brain-immune signaling may help drive neurodegeneration

A Cell perspective argues that neurodegeneration can emerge from disrupted communication between neural and immune networks, with peripheral immunity, microglia, and gene-regulatory programs all shaping disease processes. The authors propose that restoring immune homeostasis and recalibrating neuroimmune circuits could create new therapeutic and diagnostic opportunities, while emphasizing that many mechanisms remain unresolved in humans.

24 Aug 2026

Machine learning model can identify likely non-responders to exercise-based cardiac rehabilitation

Exercise training is a cornerstone of cardiac rehabilitation (CR) for patients with coronary artery disease (CAD), and current guidelines rate it as a top-tier recommendation for reducing the risk of future cardiovascular events.

21 Aug 2026

Glioma microenvironment emerges as key target for future therapies

The prognosis for glioma patients remains extremely poor despite aggressive multimodal standard therapy: maximal safe resection, radiotherapy, and temozolomide chemotherapy, with median survival rarely exceeding 15 to 18 months.

20 Aug 2026

Scintica and Indus Instruments introduce PulSAR MD: An integrated M-Mode and Doppler data acquisition system with powerful automatic analysis

Scintica and Indus Instruments are proud to introduce PULSAR MD (Preclinical Ultrasound for Small Animal Research M-Mode and Doppler) system, the next evolution in preclinical hemodynamic assessment.

From Scintica Instrumentation Inc. 20 Aug 2026

Two distinct types of brain tissue work together to support cognition in older adults

Researchers from the Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC have found that two distinct types of brain tissue work together to support cognition in older adults, and that the health of the brain's short-range wiring may help soften the cognitive effects of gray matter loss.

20 Aug 2026

Review reveals how nicotine damages blood vessels and heart health

A review published today in Nature Reviews Cardiology provides the most detailed picture yet of how nicotine damages the cardiovascular system – tracing the biological chain of events from the moment nicotine binds to receptors in blood vessel walls through to the atherosclerotic plaque rupture that triggers heart attacks and strokes.

19 Aug 2026

$Pomegranate-derived compound shows promise against preserved ejection fraction heart failure$

Vascular News and Research

Oral relaxin agonist AZD5462 improves cardiac function in heart failure patients

People with diabetes may have another reason to protect their cardiovascular health

REACT study maps widespread silent atherosclerosis across adult lifespan

Investigational anti-interleukin-6 monoclonal antibody achieves durable inflammatory biomarker reductions

New study detects silent atherosclerosis in healthy young adults

Specialized blood vessel cells found to actively drive lung fibrosis

Molecular switch ERBB4 linked to broad range of Alzheimer's pathologies

Vagus nerve stimulation may enhance long-term motor learning

New artificial lung mimics breathing and alveolar movement

Mitochondrial transplantation helps repair donor organs during machine perfusion

New study makes progress in understanding the mechanisms behind severity of HFpEF

Disrupted brain-immune signaling may help drive neurodegeneration

Machine learning model can identify likely non-responders to exercise-based cardiac rehabilitation

Glioma microenvironment emerges as key target for future therapies

Scintica and Indus Instruments introduce PulSAR MD: An integrated M-Mode and Doppler data acquisition system with powerful automatic analysis

Two distinct types of brain tissue work together to support cognition in older adults

Review reveals how nicotine damages blood vessels and heart health

Pomegranate-derived compound shows promise against preserved ejection fraction heart failure

Multi-organ chip uncovers key mechanisms behind cancer metastasis

Penn State team lays groundwork to 3D print spheroids for regenerating bone tissue

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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