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New method illuminates intricate interactions of the synaptonemal complex in nematodes

We have two copies of each chromosome in every cell in our bodies except in our reproductive cells. Sperm and egg cells contain a single copy of each chromosome with a unique mix of genes from our parents, an evolutionary trick to give our offspring genetic variability.

3 Jan 2024

Autopsy study provides new insights into yellow fever's impact on the heart

To fill gaps in knowledge of yellow fever (YF), a group of researchers in Brazil affiliated with the Department of Pathology at the University of São Paulo's Medical School (FM-USP), Hospital das Clínicas (HC, the hospital complex run by FM-USP), the Heart Institute (InCor, linked to HC) and Emílio Ribas Institute of Infectious Diseases (IIER) decided to study the pathogenesis of YF-associated heart injury.

19 Dec 2023

Immunoregulatory nanomedicines for the prevention and treatment of respiratory diseases

Study explores immunoregulatory nanomedicines for respiratory infections, highlighting their potential in enhancing treatment outcomes and vaccine efficacy.

7 Dec 2023

UVA researchers discover how Lactobacillus may help prevent depression and anxiety

University of Virginia School of Medicine researchers have discovered how Lactobacillus, a bacterium found in fermented foods and yogurt, helps the body manage stress and may help prevent depression and anxiety. The findings open the door to new therapies to treat anxiety, depression and other mental-health conditions.

4 Dec 2023

Machine learning unlocks secrets of antimicrobial resistance, identifying over 900 key genes

Researchers employed advanced techniques like gene annotation, pangenomics, and machine learning to identify over 900 genes responsible for antimicrobial resistance in 12 bacterial species, outperforming traditional identification methods. This breakthrough approach offers new insights into the genetic basis of resistance, potentially guiding the development of more effective antibiotics

27 Nov 2023

Novel method can detect contaminants in T-cell cultures within 24 hours

Researchers from Critical Analytics for Manufacturing Personalized-Medicine (CAMP) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, in collaboration with Singapore Centre for Environmental Life Sciences Engineering (SCELSE) and Massachusetts Institute of Technology (MIT), have developed a novel method capable of identifying contaminants in T-cell cultures within 24 hours.

27 Nov 2023

Study identifies common skin bacterium as previously unknown culprit behind itch

Scientists at Harvard Medical School have shown for the first time that a common skin bacterium -; Staphylococcus aureus -; can cause itch by acting directly on nerve cells.

22 Nov 2023

Study shows how probiotic Bifidobacteria longum can help relieve constipation

Scientists have identified the genes in the probiotic Bifidobacteria longum responsible for improving gut motility.

21 Nov 2023

Micronutrient deficiencies linked to gut microbiome shifts and antibiotic resistance

University of B.C. researchers have uncovered startling connections between micronutrient deficiencies and the composition of gut microbiomes in early life that could help explain why resistance to antibiotics has been rising across the globe.

17 Nov 2023

Bacteria fight phages with RNA-based immune defense

There's no organism on earth that lives free of threat-;including bacteria. Predatory viruses known as phages are among their most dire foes, infiltrating their cells to replicate and take over.

15 Nov 2023

Sir Peter Barnes on World COPD Day: Awareness, Advances, and the Road Ahead

In this interview, we delve into the remarkable journey of Professor Sir Peter Barnes, a leading figure in respiratory medicine.

15 Nov 2023

Scientists discover kidney-friendly antifungal that evades resistance

In this investigation, researchers produced powerful antifungals of the polyene class without nephrotoxicity.

9 Nov 2023

New antifungal molecule shows promise in combatting fungal infections without toxicity

A new antifungal molecule, devised by tweaking the structure of prominent antifungal drug Amphotericin B, has the potential to harness the drug's power against fungal infections while doing away with its toxicity, researchers at the University of Illinois Urbana-Champaign and collaborators at the University of Wisconsin-Madison report in the journal Nature.

8 Nov 2023

Fresh risks in ready-to-eat produce: Study reveals how common pathogens lurk in our salads

This research paper delves into the risks of contamination in ready-to-eat fruits and vegetables by enteric pathogens like E. coli, Salmonella, and Listeria, which can lead to foodborne illnesses. It also explores the contamination sources and plant-pathogen interactions, emphasizing the importance of improved safety measures in the food supply chain.

6 Nov 2023

New gene editing method creates first mice with human-like COVID-19

Researchers have genetically engineered the first mice that get a human-like form of COVID-19, according to a study published online November 1 in Nature.

1 Nov 2023

Advances in grain research illuminate potential for precision nutrition in clinical settings

Grains are a primary source of energy (calories) in the diet.

1 Nov 2023

Fungi used to produce food products have potential probiotic effects on gut inflammation

Many fungus strains have been used and selected by the food industry for their capacities to ferment, produce flavors or produce heterologous molecules.

26 Oct 2023

Fighting invisible foes: How cryptic fungal pathogens threaten human health and food security

The research paper in PLOS Pathogens delves into the challenges of diagnosing and treating cryptic fungal pathogens, which are difficult to distinguish from common fungi but equally dangerous. The study calls for more accurate diagnostic methods and a better understanding of how these fungi interact with the human immune system and microbiome for effective treatment and prevention.

25 Oct 2023

Study sheds light on role of gut fungi in severe COVID-19 and long COVID

Certain gut-dwelling fungi flourish in severe cases of COVID-19, amplifying the excessive inflammation that drives this disease while also causing long-lasting changes in the immune system, according to a new study led by investigators at Weill Cornell Medicine and NewYork-Presbyterian.

24 Oct 2023

Genomic surveillance could help detect and slow the spread of deadly 'superbugs'

Harnessing new advances in genomic surveillance technology could help detect the rise of deadly 'superbugs' and slow their evolution and spread, improving global health outcomes, a new Australian study suggests.