Animal Model News and Research

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Research provides new insight into how Crimean-Congo hemorrhagic fever virus causes disease

Army scientists determined that the body's own natural immune response contributes to disease severity in mice infected with Crimean-Congo hemorrhagic fever virus (CCHFV), which causes a widespread tick-borne viral infection in humans.

20 May 2022

Pioneering study could transform the treatment landscape for babies with infantile spasms

Infantile spasm (IS) is a severe epileptic syndrome of infancy and accounts for 50% of all epilepsy cases that occur in babies during the first year of life.

20 May 2022

Evaluating efficacy of SARS-CoV-2 antivirals in a mouse model

In a recent study posted to the bioRxiv* pre-print server, researchers from Belgium evaluated the efficacy of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antiviral drugs in a severe combined immunodeficient (SCID) mouse model.

18 May 2022

Cannabidiol for Parkinson's disease symptom management

Scientists have published a review study in the Journal for Nurse Practitioners that has focussed on various aspects of the use of cannabidiol in Parkinson's.

17 May 2022

Novel approach allows islet transplants to survive and control diabetes

In type 1 diabetes, an autoimmune response attacks the pancreas's insulin-producing beta cells, leading to marked fluctuations in blood sugar levels. Lifelong daily insulin treatments are standard for patients, but replacing lost beta cells through transplants of islets, a group of cells in the pancreas, represents an attractive option.

13 May 2022

Novel Type 1 diabetes treatment involves pancreatic islet transplant without the need for immunosuppression

In a new study, a team of researchers from the University of Missouri, Georgia Tech and Harvard University has demonstrated the successful use of a novel Type 1 diabetes treatment in a large animal model.

13 May 2022

Study shows how co-transplanting islet cells with SA-FasL-microgels reverses diabetic symptoms

Islet cell transplants are a promising treatment that can cure difficult-to-treat type 1 diabetes. The cells, taken from a donor pancreas, provide patients with a sustainable and tightly controlled source of insulin.

13 May 2022

Discovery of new structure in the egg cells of zebrafish could provide insights into human reproduction

It is humbling to realize that we humans share about 70% of our genes with zebrafish. There are also a whole host of other similarities that make these small transparent fish an ideal animal model for the study of many human diseases and biological processes.

12 May 2022

Deficiency of YWHAZ gene alters neurodevelopmental process in zebrafish

An article published in the journal Molecular Psychiatry reveals the molecular mechanisms to explain how the YWHAZ gene –related to psychiatric and neurological disorders such as autism and schizophrenia– can alter the neurodevelopmental process.

10 May 2022

Researchers discover a bi-directional neural network connecting the legs and visual system to shape walking

A fruit fly walks on a small styrofoam ball fashioned into a floating 3D treadmill. The room is completely dark, and yet, an electrode recording visual neurons in the fly's brain relays a mysterious stream of neural activity, rising and falling like a sinusoidal wave.

6 May 2022

Epigenetic abnormalities in hematopoietic cells during fetal development cause idiopathic autism

An international research group led by Professor Toru Takumi (Senior Visiting Scientist, RIKEN Center for Biosystems Dynamics Research) and Researcher Chia-wen Lin at Kobe University Graduate School of Medicine has shown that idiopathic autism is caused by epigenetic abnormalities in hematopoietic cells during fetal development, which results in immune dysregulation in the brain and gut.

2 May 2022

Combination therapy shows promise for treating triple-negative breast cancer

Researchers at Baylor College of Medicine and collaborating institutions have identified a combination therapy for treating triple-negative breast cancer (TNBC) that results in durable tumor regression in an animal model of the condition.

27 Apr 2022

Gene discovery could pave the way for new and more effective treatments for lupus

Researchers from The Australian National University have identified a gene called TLR7 that, when over-activated, is responsible for causing lupus, an autoimmune disease that can be life-threatening in severe cases.

27 Apr 2022

MCG scientists report how exercise can counter the damage of diabetes

One way exercise can counter the damage of diabetes is by enabling activation of a natural system we have to grow new blood vessels when existing ones are ravaged by this disease, scientists report.

26 Apr 2022

New discovery helps better understand how the brain processes information

For years, the brain has been thought of as a biological computer that processes information through traditional circuits, whereby data zips straight from one cell to another.

22 Apr 2022

Scientists identify innovative treatment approach for arterial thromboses

Scientists have shown in an animal model that the CXCL12 messenger could be suitable as a target structure for the treatment of blood-clotting disorders.

21 Apr 2022

Using CR2Crry to reduce the negative effects of brain hemorrhaging in premature infants

A little over 1% of babies born in the U.S. in 2020 fell under the category of very low birthweight, meaning they weighed less than 1,500 grams at birth or 3 pounds, 4 ounces. And considering that the Centers for Disease Control and Prevention says more than 3.5 million babies were born that year, almost 48,500 were considered to be at very low birthweight.

21 Apr 2022

Animal Model News and Research

Research provides new insight into how Crimean-Congo hemorrhagic fever virus causes disease

Pioneering study could transform the treatment landscape for babies with infantile spasms

Evaluating efficacy of SARS-CoV-2 antivirals in a mouse model

Cannabidiol for Parkinson's disease symptom management

Novel approach allows islet transplants to survive and control diabetes

Novel Type 1 diabetes treatment involves pancreatic islet transplant without the need for immunosuppression

Study shows how co-transplanting islet cells with SA-FasL-microgels reverses diabetic symptoms

Discovery of new structure in the egg cells of zebrafish could provide insights into human reproduction

Deficiency of YWHAZ gene alters neurodevelopmental process in zebrafish

Researchers discover a bi-directional neural network connecting the legs and visual system to shape walking

Epigenetic abnormalities in hematopoietic cells during fetal development cause idiopathic autism

Combination therapy shows promise for treating triple-negative breast cancer

Gene discovery could pave the way for new and more effective treatments for lupus

MCG scientists report how exercise can counter the damage of diabetes

New discovery helps better understand how the brain processes information

Scientists identify innovative treatment approach for arterial thromboses

Using CR2Crry to reduce the negative effects of brain hemorrhaging in premature infants

Autonomous robot performs laparoscopic soft tissue surgery with minimal assistance from a surgeon

A new approach for treating multiple-drug resistant bacteria

Type I interferon found to be major driver of memory, cognitive loss in Alzheimer's disease mouse model

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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