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UCL researchers discover how HIV infects macrophages despite presence of protective protein

A team led by UCL researchers has identified how HIV is able to infect macrophages, a type of white blood cell integral to the immune system, despite the presence of a protective protein.

27 Jan 2017

Researchers design antibody that recognizes and destroys blood cancer stem cells

A protein-sugar molecule, CD99, occurs more frequently than normal on stem cells responsible for blood cancers, including acute myeloid leukemia (AML) and the related myelodysplastic syndromes.

25 Jan 2017

Shorter chromosome 'caps' linked to higher burden of disease later in life

New research indicates that people who had more infections as babies harbor a key marker of cellular aging as young adults: the protective stretches of DNA which "cap" the ends of their chromosomes are shorter than in adults who were healthier as infants.

25 Jan 2017

Researchers show how MPO enzyme kills pathogens without collateral tissue damage

Researchers from the University of Basel in Switzerland have clarified the role of the enzyme MPO.

24 Jan 2017

New research exposes cellular responses linked to bird flu vaccine

New research from Vanderbilt eavesdrops on gene expression in human immune system cells before and after vaccination against bird flu.

19 Jan 2017

Study provides link between common mutations in blood cells of older adults and atherosclerosis

A new study provides some of the first links between relatively common mutations in the blood cells of elderly humans and atherosclerosis.

19 Jan 2017

Endogenous peptide inhibits atherosclerosis by reducing cholesterol levels

Cells of the innate immune system that play an important role in development of atherosclerosis contain a protein that reduces levels of cholesterol in mice - and thus helps to inhibit or mitigate the disease.

19 Jan 2017

Study reveals brain activity may be key to link between stress and heart disease

Increased activity in a deep-lying region of the brain called the amygdala is associated with a higher risk of heart attack and stroke, according to a study published in The Lancet. The amygdala is known to process emotions such as fear and anger and the finding sheds light on the possible mechanism by which stress can lead to cardiovascular disease (CVD), say the study authors.

12 Jan 2017

Scientists identify Smurf1 protein that plays role in autophagy of TB bacteria

UT Southwestern Medical Center researchers have identified a protein that is central to the immune system's ability to recognize and destroy the bacterium responsible for the global tuberculosis (TB) epidemic.

12 Jan 2017

Unique type of airway inflammation could make African Americans less responsive to asthma treatment

African Americans may be less responsive to asthma treatment and more likely to die from the condition, in part, because they have a unique type of airway inflammation, according to a study led by researchers at the University of Illinois at Chicago College of Medicine.

6 Jan 2017

High-fiber diet may inhibit gout-related inflammation

New research published in the Journal of Leukocyte Biology, shows that a high-fiber diet likely inhibits gout-related inflammation caused by monosodium urate (MSU) crystals.

4 Jan 2017

Persistent infection in infant reveals mutation that helps bacteria tolerate antibiotic therapy

The quest to understand a prolonged infection in an infant being treated for leukemia has led to the St. Jude Children's Research Hospital discovery of a mutation that allows bacteria to tolerate normally effective antibiotic therapy. The report appears today in the scientific journal mBio.

3 Jan 2017

Powerful version of anti-inflammatory molecule may help protect vision in diabetic retinopathy

A more powerful version of an anti-inflammatory molecule already circulating in our blood may help protect our vision in the face of diabetes.

3 Jan 2017

NIH researchers identify molecular mechanisms that may underlie woman's susceptibility to PMDD

National Institutes of Health researchers have discovered molecular mechanisms that may underlie a woman's susceptibility to disabling irritability, sadness, and anxiety in the days leading up to her menstrual period.

3 Jan 2017

Scientists identify sugar molecule that reduces inflammatory response and COPD progression

Using a mouse model, scientists from the RIKEN-Max Planck Joint Research Center for Systems Chemical Biology and a number of other institutes have identified a sugar molecule that reduced the inflammatory response and progress of emphysema, a common component of chronic obstructive pulmonary disease (COPD).

27 Dec 2016

Localized chemotherapy may be effective way to keep immune system intact, animal study suggests

In experiments on mice with a form of aggressive brain cancer, Johns Hopkins researchers have shown that localized chemotherapy delivered directly to the brain rather than given systemically may be the best way to keep the immune system intact and strong when immunotherapy is also part of the treatment.

22 Dec 2016

Leukocyte News and Research

UCL researchers discover how HIV infects macrophages despite presence of protective protein

Researchers design antibody that recognizes and destroys blood cancer stem cells

Shorter chromosome 'caps' linked to higher burden of disease later in life

Researchers show how MPO enzyme kills pathogens without collateral tissue damage

New research exposes cellular responses linked to bird flu vaccine

Study provides link between common mutations in blood cells of older adults and atherosclerosis

Endogenous peptide inhibits atherosclerosis by reducing cholesterol levels

Study reveals brain activity may be key to link between stress and heart disease

Scientists identify Smurf1 protein that plays role in autophagy of TB bacteria

Unique type of airway inflammation could make African Americans less responsive to asthma treatment

High-fiber diet may inhibit gout-related inflammation

Persistent infection in infant reveals mutation that helps bacteria tolerate antibiotic therapy

Powerful version of anti-inflammatory molecule may help protect vision in diabetic retinopathy

NIH researchers identify molecular mechanisms that may underlie woman's susceptibility to PMDD

Scientists identify sugar molecule that reduces inflammatory response and COPD progression

Localized chemotherapy may be effective way to keep immune system intact, animal study suggests

Researcher develops new method to accurately identify elusive molecules

Biomarker for oxidative stress plays key role in development of NAFLD, study shows

Research findings reveal new powerful role of sunlight on immunity

TUM researchers discover vital mechanism in the body's defenses against fungal infections

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