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Tracing the path of depression

David Nutt, Professor of Psychopharmacology, said: "The development of one of these radioactive tracers to enable the study of noradrenaline and its related processes in those suffering depression is critical to our proper understanding of this disease.

27 May 2007

Merits and risks of postmenopausal hormone therapy

The study was categorized as a primary prevention trial for coronary heart disease, although the fact that mean age at recruitment was 63 years was not given enough importance at that time. WHI investigators concluded that hormone therapy (HT) was not cardioprotective, and, in fact, its riskbenefit ratio did not favor the use of postmenopausal hormones for prevention of chronic diseases.

17 May 2007

Electroconvulsive therapy helps patients with severe depression who don't respond to other treatments

Electroconvulsive therapy has been shown to be a highly effective, safe, and even life-saving treatment for persistent and severe depression, bipolar disorder, and schizophrenia.

8 May 2007

Discovery of molecular mechanism that alters strength of higher brain network connections

Yale School of Medicine and University of Crete School of Medicine researchers report in Cell April 20 the first evidence of a molecular mechanism that dynamically alters the strength of higher brain network connections.

21 Apr 2007

A candidate neural circuit for stress-induced analgesia

Recent statistics indicate that one in five people worldwide suffer from moderate to severe chronic pain and that one in three are unable or less able to maintain an independent lifestyle due to their pain.

17 Apr 2007

Prazosin drug helps posttraumatic stress disorder nightmares

A generic drug already used by millions of Americans for high blood pressure and prostate problems has been found to improve sleep and lessen trauma nightmares in veterans with posttraumatic stress disorder (PTSD).

12 Apr 2007

FDA approves antidepressant Cymbalta (duloxetine HCl) for treatment of generalized anxiety disorder

Eli Lilly and Company announced today that the U.S. Food and Drug Administration (FDA) has approved the antidepressant Cymbalta (duloxetine HCl) for the treatment of generalized anxiety disorder (GAD), a condition that affects more than 6.5 million American adults in a given year.

26 Feb 2007

CeNeRx BioPharma starts human trials of RIMA antidepressant

CeNeRx BioPharma, Inc. has announced the initiation of human clinical trials of Tyrima, CeNeRx's new drug candidate with a triple mechanism of action for the treatment of depression and anxiety.

30 Jan 2007

Taste may give a clue in how to treat depression

Researchers in the UK have found that taste tests could determine the cause of depression in patients and also indicate which is the best drug to treat the illness.

6 Dec 2006

Guanfacine no more effective than a placebo

Guanfacine, a medication commonly prescribed to alleviate symptoms of post-traumatic stress disorder, is no more effective than a placebo, according to a study led by researchers at the San Francisco VA Medical Center.

2 Dec 2006

Safety of t-PA clot-busting therapy questioned

Across the world, emergency medical teams often administer a powerful clot-busting drug called tissue plasminogen activator (t-PA) to help patients stricken by heart attack.

13 Nov 2006

Nicotine shows potential medical benefits

Nicotine may improve the symptoms of depression in people who do not smoke, Duke University Medical Center scientists have discovered.

12 Sep 2006

Study shows how ADHD drugs Adderall, Ritalin and Dexedrine work in brain

Although millions depend on medications such as Ritalin to quell symptoms of attention deficit hyperactivity disorder (ADHD), scientists have struggled to pinpoint how the drugs work in the brain.

27 Jun 2006

Duloxetine proven effective for use in men with stress urinary incontinence after radical prostatectomy

Up to 33% of patients undergoing radical prostatectomy suffer from varying degrees of incontinence.

13 Jun 2006

Lower income, education lead to greater stress levels

People with low incomes are more likely to be under stress than their wealthier peers

23 May 2006

Study helps explain why aerobic training helps heart failure patients

Aerobic training is associated with a reversal of abnormal hormonal patterns that underlie many of the debilitating symptoms of heart failure, according to a new study in the Journal of the American College of Cardiology.

3 May 2006

New orthostatic hypotension treatment reduces symptoms without causing high blood pressure

A drug traditionally used to treat myasthenia gravis shows potential benefit for reducing symptoms of orthostatic hypotension without raising blood pressure when people lie down, according to results of a double-blind, controlled clinical trial.

19 Apr 2006

Enzyme released by cardiac mast cells during heart attack contributes to arrhythmia

In times of cardiac crisis, mast cells in the heart secrete a powerful enzyme, renin, that indirectly triggers dangerous arrhythmias, according to a team of researchers at the Weill Medical College of Cornell University in New York City.

4 Apr 2006

Gene linked to impulsive violence weakens brain circuits that regulate thinking in humans

A version of a gene previously linked to impulsive violence appears to weaken brain circuits that regulate impulses, emotional memory and thinking in humans, researchers at the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH) have found.

21 Mar 2006

Psychological wellbeing has biological consequences

An experimental investigation by Carol Ryff and associates (University of Wisconsin), published in the March issue of the journal of Psychotherapy & Psychosomatics, underscores the biological consequences of psychological well-being.

13 Mar 2006