Remdesivir News and Research

RSS

Montefiore and Einstein evaluate a new drug combination to fight COVID-19

Montefiore Health System Albert Einstein College of Medicine have begun the next stage of the Adaptive COVID-19 Treatment Trial (ACTT), to evaluate treatment options for people hospitalized with severe COVID-19 infection.

26 May 2020

Zero benefit of Hydroxychloroquine or Chloroquine in COVID-19, says extensive study

The purported "game-changer" anti-malarial drug Hydroxychloroquine, which was claimed to be effective in preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and also helping better outcomes in COVID-19 patients, seems to have failed in clinical trials.

25 May 2020

Using Qigong to manage COVID-19 in older adults

A recent study published in The American Journal of Geriatric Psychiatry in May 2020 reports on the possible usefulness of the integrative practice called Qigong to prevent and manage COVID-19 in older adults.

25 May 2020

Children with COVID-19 presenting with sudden severe lung disease

Even as the COVID-19 pandemic continues to seek out new victims, puzzling new presentations are further confusing the situation. A new study published online in The Lancet Rheumatology in May 2020 reports a case of severe COVID-19 in a child who rapidly developed acute respiratory distress symptoms without prior respiratory symptoms. This case should alert clinicians to consider this diagnosis in children as well.

24 May 2020

Lifesaving innovation for COVID-19 will increase the already existing racial inequalities

As is the case with most fatal diseases, coronavirus disease (COVID-19) is already taking a disproportionate toll on black Americans and other disadvantaged minorities.

20 May 2020

Taking blood pressure medicines as usual is important during COVID-19 pandemic

Keeping your blood pressure under control is especially important during the COVID-19 pandemic – so keep taking your blood pressure medicines!

20 May 2020

Three FDA-approved drugs can block the replication of COVID-19 virus

Three drugs that are already approved by the Food and Drug Administration (FDA) or other international agencies can block the production of the novel coronavirus that causes COVID-19 in human cells, according to computational and pharmaceutical studies performed by UT Southwestern scientists.

19 May 2020

ECMO machine can be useful for treating critically ill COVID-19 patients

When COVID-19 patients are critically ill, the biggest threat to their lives is lung dysfunction. If their lungs don't work, their blood can't circulate enough oxygen to the brain, the liver and other organs.

18 May 2020

Scant clinical research for pregnant and lactating women with COVID-19

Pregnant and breastfeeding women have been excluded from clinical trials of drugs to treat COVID-19, and as result, there is no safety data to inform clinical decisions. Such drugs include remdesivir according to a new article in the peer-reviewed journal Breastfeeding Medicine.

18 May 2020

Drugmakers tout COVID-19 vaccines to refurbish their public image

Johnson & Johnson researchers working on a vaccine against the coronavirus are "just like the heroes in the hospitals" fighting to save patients, J&J CEO Alex Gorsky said on the "Today" show a few weeks ago.

18 May 2020

COVID-19 clinical trials show positive early results, says GlobalData

With the number of COVID-19 cases and deaths increasing with each passing day, the need for a therapeutic or a vaccine for the pandemic intensifies.

18 May 2020

COVID-19’s adverse impact on the cardiovascular system

COVID-19 can cause serious cardiovascular complications including heart failure, heart attacks and blood clots that can lead to strokes, emergency medicine doctors report in a new scientific paper.

15 May 2020

Chasing the elusive dream of a COVID cure

Although scientists and stock markets have celebrated the approval for emergency use of remdesivir to treat COVID-19, a cure for the disease that has killed nearly 260,000 people remains a long way off — and might never arrive.

15 May 2020

Study shows 19 out of 25 COVID-19 patients improved with convalescent plasma treatment

The country's first convalescent plasma transfusion trial results have been published and show 19 out of 25 patients improved with the treatment, and 11 were discharged from the hospital.

13 May 2020

UCI Health to initiate clinical trial of a drug to treat critically ill COVID-19 patients

UCI Health will initiate a clinical study of a drug to treat critically ill COVID-19 patients who face a high mortality rate because of acute inflammation that fills their lungs with fluid, a grave condition that even mechanical ventilation cannot improve.

13 May 2020

Study shows why older individuals are vulnerable to COVID-19

A group of tiny RNA that should attack the virus causing COVID-19 when it tries to infect the body are diminished with age and chronic health problems, a decrease that likely helps explain why older individuals and those with preexisting medical conditions are vulnerable populations, investigators report.

13 May 2020

Perspective: Existing drugs could be repurposed for COVID-19 patients

Given the rapid spread of COVID-19 and its relatively high mortality, filling the gap for coronavirus-specific drugs is urgent.

9 May 2020

NIH clinical trial evaluates antiviral plus anti-inflammatory drug for COVID-19

A randomized, controlled clinical trial evaluating the safety and efficacy of a treatment regimen of the investigational antiviral remdesivir plus the anti-inflammatory drug baricitinib for coronavirus disease 2019 (COVID-19) has begun.

8 May 2020

Repurposing existing drugs is a more rapid alternative than developing COVID-19 vaccine

Repurposing existing medicines focused on known drug targets is likely to offer a more rapid hope of tackling COVID-19 than developing and manufacturing a vaccine, argue an international team of scientists in the British Journal of Pharmacology today.

8 May 2020

Most COVID-19 patients lose sense of smell by the third day, shows study

A University of Cincinnati researcher says a study of COVID-19 patients shows loss of the sense of smell is most likely to occur by the third day of infection with the novel virus. Most of these patients are also experiencing a loss of the sense of taste.

8 May 2020