Spike Protein News and Research

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SARS-CoV-2 Omicron BA.2.75 replicates more efficiently than BA.2 or BA.5 sub-variants

In a new study, researchers characterized the clinical isolates of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.2.75 sub-variant.

30 Aug 2022

Understanding recombination rates in RNA viruses

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30 Aug 2022

Disrupting a virus’s genome packaging can halt replication, study finds

Like savvy international travelers, viruses know exactly how to pack. With the genetic instructions for the next generation folded just so, snuggled into a custom-made outer covering studded with cell-grabbing proteins, these tiny invaders quest for new digs on the reg.

30 Aug 2022

Researchers report the exceptional binding and neutralizing potency of an ACE2 decoy against SARS-CoV-2 variants

Researchers explored the activity of an ACE2 decoy against SARS-CoV-2 Omicron variant.

30 Aug 2022

Exploration of glycan shield structure of sarbecoviruses provides new insights into developing pan-coronavirus vaccines

A new study explored the glycan shield diversity of sarbecoviruses, furthering the knowledge for developing broad-range pan-coronavirus vaccines.

30 Aug 2022

New study provides comparison of replicating and non-replicating vaccines against SARS-CoV-2

A new study reported a single-cell adenovirus (SC-Ad) which replicates the antigen genes substantially without producing infectious progeny.

26 Aug 2022

COVID-19 pandemic: An epidemiological update

Epidemics and pandemics have been frightening the human chase again and again. SARS, H1N1, Ebola, and more have exposed their real face in the past, but with every such outbreak.

25 Aug 2022

Researchers report large molecular compounds and nanoscale nanozyme of two traditional Chinese medicines may inhibit COVID-19 signaling

Researchers investigated the potential anti-COVID-19 activity of traditional Chinese medicine.

25 Aug 2022

What is the stability of SARS-CoV-2 strains in human biological fluids?

In a new study, researchers assessed the stability of ancestral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineage in human biological fluids.

24 Aug 2022

Updated guidelines on the Valneva SARS-CoV-2 vaccine

The WHO provides interim guidelines for the use of the Valneva vaccine.

23 Aug 2022

Investigating the missing link between COVID-19 and anosmia

A new study evaluated how SARS-CoV-2 infection leads to anosmia via chromatin structure disruption and OR dysregulation. For this purpose, publicly available Hi-C data of OSNs of SARS-CoV-2-infected and control human subjects were used.

23 Aug 2022

Epistasis leads to the reduction in genetic barrier to COVID-19 neutralizing antibody escape

A new study addresses the important question of how the SARS-CoV-2 virus would evolve in the future to be able to escape diverse and broadly neutralizing antibodies.

23 Aug 2022

SARS-CoV-2 breakthrough infection induces virus-specific nasal T-cells

A new study reports that hybrid immunity induced by vaccination and previous infection induces SARS-CoV-2-specific tissue-resident T-cells in the nasal cavity.

22 Aug 2022

How natural alterations inside the SARS-CoV-2 glycan barrier affect spike protein dynamics

Researchers explored how the natural alterations inside the SARS-CoV-2 glycan barrier affect the spike protein dynamics.

22 Aug 2022

Cedars-Sinai investigators propose a theory for the cause of post-COVID syndromes

Investigators at Cedars-Sinai have proposed a theory for how SARS-CoV-2, the virus that causes COVID-19, infects the body. Their hypothesis, published in Frontiers in Immunology, could explain why some people still have symptoms long after the initial infection.

19 Aug 2022

SARS-CoV-2 evolution within hosts and vaccination effects

A new study explores the mutational profiles within individuals infected with SARS-CoV-2.

16 Aug 2022

Rapid and efficient strategy for the development and design of SARS-CoV-2 neutralizing humanized nanobody constructs

Researchers developed humanized nanobodies that neutralize SARS-CoV-2.

16 Aug 2022

Scientists explore nanomolar inhibition of SARS-CoV-2 infection via unmodified peptide targeting spike protein pre-hairpin intermediate

In a new study, scientists identified an unmodified peptide addressing pre-hairpin spike (S) protein intermediate inhibiting SARS-CoV-2 infection.

15 Aug 2022

SARS-CoV-2 S protein and RNA fragments remain in convalescent SARS-CoV-2 patients with PASC

Researchers evaluated circulating SARS-CoV-2 elements in long coronavirus disease.

15 Aug 2022

Is the level of circulating SARS-CoV-2 RNA or spike protein associated with acute disease severity?

Researchers investigated the levels of circulating SARS-CoV-2 spike protein and viral RNA among patients hospitalized with acute COVID-19 and in patients with and without post-acute sequelae of COVID-19.

15 Aug 2022

Spike Protein News and Research

SARS-CoV-2 Omicron BA.2.75 replicates more efficiently than BA.2 or BA.5 sub-variants

Understanding recombination rates in RNA viruses

Disrupting a virus’s genome packaging can halt replication, study finds

Researchers report the exceptional binding and neutralizing potency of an ACE2 decoy against SARS-CoV-2 variants

Exploration of glycan shield structure of sarbecoviruses provides new insights into developing pan-coronavirus vaccines

New study provides comparison of replicating and non-replicating vaccines against SARS-CoV-2

COVID-19 pandemic: An epidemiological update

Researchers report large molecular compounds and nanoscale nanozyme of two traditional Chinese medicines may inhibit COVID-19 signaling

What is the stability of SARS-CoV-2 strains in human biological fluids?

Updated guidelines on the Valneva SARS-CoV-2 vaccine

Investigating the missing link between COVID-19 and anosmia

Epistasis leads to the reduction in genetic barrier to COVID-19 neutralizing antibody escape

SARS-CoV-2 breakthrough infection induces virus-specific nasal T-cells

How natural alterations inside the SARS-CoV-2 glycan barrier affect spike protein dynamics

Cedars-Sinai investigators propose a theory for the cause of post-COVID syndromes

SARS-CoV-2 evolution within hosts and vaccination effects

Rapid and efficient strategy for the development and design of SARS-CoV-2 neutralizing humanized nanobody constructs

Scientists explore nanomolar inhibition of SARS-CoV-2 infection via unmodified peptide targeting spike protein pre-hairpin intermediate

SARS-CoV-2 S protein and RNA fragments remain in convalescent SARS-CoV-2 patients with PASC

Is the level of circulating SARS-CoV-2 RNA or spike protein associated with acute disease severity?

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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