Genes News and Research

RSS

UTSW researchers identify molecular function of 87 inherited genetic variants linked to prostate cancer

UT Southwestern researchers have identified the molecular function of 87 inherited genetic variants that affect the risk of prostate cancer, and the majority appear to control the activity of genes located far away from the risk variants themselves.

23 Dec 2022

New technology achieves 99.7% purity in sorting target cells in real-time

Researchers from the Qingdao Institute of Bioenergy and Bioprocess Technology of the Chinese Academy of Sciences have proposed a new technology, called optical tweezer-assisted pool-screening and single-cell isolation (OPSI) system, which achieves 99.7% purity of sorting target cells, with all done in real-time.

23 Dec 2022

Scientists study OAS–RNase L errors and COVID-19-associated multisystem inflammatory syndrome in children

Researchers assessed the inborn abnormalities of 2′-5′-oligoadenylate synthetase (OAS)-ribonuclease L (RNASEL) noted in coronavirus disease 2019 (COVID-19)-associated multisystem inflammatory syndrome in children (MIS-C).

23 Dec 2022

Study shows de novo origination of functional microproteins

In a new study, researchers performed a genomic analysis to investigate the origination of human microproteins of biological importance.

23 Dec 2022

UC San Diego researchers rewrite the textbook on gene regulation

A fundamental principle of molecular biology governs how proteins are made within the cell, which happens in two stages called transcription and translation.

22 Dec 2022

Decade-long search in one-celled, fresh water dwelling organism solves puzzle involved in gene regulation

After an intrepid, decade-long search, Johns Hopkins Medicine scientists say they have found a new role for a pair of enzymes that regulate genome function and, when missing or mutated, are linked to diseases such as brain tumors, blood cancers and Kleefstra syndrome - a rare genetic, neurocognitive disorder.

22 Dec 2022

PTSD, TBI, and a genetic variant show strong links with Alzheimer's Disease and related dementias

The medical community has never researched the simultaneous impact of post-traumatic stress disorder (PTSD), traumatic brain injury (TBI), and genetic risk factors in a large cohort … until now.

22 Dec 2022

Impact of epigenetics on the clinical management of cancer patients

Dr. Manel Esteller and Dr. Verónica Dávalos, researchers at the Josep Carreras Leukaemia Research Institute, describe in a new article the impact of epigenetics on cancer treatment and how it has become a crucial tool to improve early detection, predict disease progression and become a target for new treatments.

22 Dec 2022

Study increases understanding of the genetic architecture of dementia risk in African ancestry populations

In the largest-ever genetic study of dementia in people of African ancestry, VA researchers identified several genetic risks different from those seen in people of European ancestry.

22 Dec 2022

New methods can advance the development of rapid diagnostics for many infectious diseases

Two companion studies report new artificial intelligence approaches for identification of molecular "fingerprints" for specific infections. The methods, used here to derive a fingerprint for COVID-19, can advance the development of rapid diagnostics for many infectious diseases.

21 Dec 2022

Mutations responsible for common inherited heart condition corrected using CRISPR-Cas9 therapy

Using the CRISPR-Cas9 gene editing system, UT Southwestern researchers corrected mutations responsible for a common inherited heart condition called dilated cardiomyopathy (DCM) in human cells and a mouse model of the disease.

21 Dec 2022

Research could pave way for designing more strategically engineered transplants to treat cartilage damage in the joints

A collaborative team, which includes scientists from the Terasaki Institute for Biomedical Innovation, University of Illinois Chicago, and Pohang University of Science and Technology has elucidated some key points on how the generation of cartilage in the joints is facilitated and how alternative bone formation can be avoided.

21 Dec 2022

Research links mutation that causes Huntington's disease to developmental deficits in the brain's oligodendrocyte cells

A research team led by the University of California, Irvine has linked the mutation that causes Huntington's disease to developmental deficits in the brain's oligodendrocyte cells that are caused by changes in metabolism.

21 Dec 2022

Study explores cellular alterations in six distinct neurodegenerative diseases

A perplexing range of neurodegenerative diseases are known to attack distinct regions of the brain, causing severe cognitive and motor deficit.

21 Dec 2022

Huge multi-omic data analysis deciphers colorectal cancer genetics

An analysis of more than 100,000 colorectal cancer cases and 154,000 healthy controls published in Nature Genetics uncovered hundreds of signals that may serve as new treatment and prevention targets.

21 Dec 2022

IU researchers uncover new ways to prevent serious side effects for breast cancer patients

Researchers at Indiana University School of Medicine are learning more about ways to prevent serious side effects from chemotherapy used to treat breast cancer patients.

20 Dec 2022

Research estimates the evolutionary origins of functional human microgenes

Modern humans evolutionarily split from our chimpanzee ancestors nearly 7 million years ago, yet we are continuing to evolve.

20 Dec 2022

Research uncovers a new way to boost the effectiveness of RNA therapies

Investigators from the Smidt Heart Institute at Cedars-Sinai have identified how biological pacemaker cells - cells that control your heartbeat - can "fight back" against therapies to biologically correct abnormal heartbeat rates.

20 Dec 2022

Study shows common synthetic food dye as a potential dietary trigger for IBDs

Long-term consumption of Allura Red food dye can be a potential trigger of inflammatory bowel diseases (IBDs), Crohn's disease and ulcerative colitis, says McMaster University's Waliul Khan.

20 Dec 2022

Analysis finds more than 100 new genetic risk factors strongly linked to colorectal cancer

A comprehensive analysis of more than 100,000 colorectal cancer (CRC) cases, led by researchers at the Fred Hutchinson Cancer Center in Seattle and 200 scientific collaborators worldwide, has identified more than 100 new genetic risk factors strongly linked with the disease.

20 Dec 2022

Genes News and Research

UTSW researchers identify molecular function of 87 inherited genetic variants linked to prostate cancer

New technology achieves 99.7% purity in sorting target cells in real-time

Scientists study OAS–RNase L errors and COVID-19-associated multisystem inflammatory syndrome in children

Study shows de novo origination of functional microproteins

UC San Diego researchers rewrite the textbook on gene regulation

Decade-long search in one-celled, fresh water dwelling organism solves puzzle involved in gene regulation

PTSD, TBI, and a genetic variant show strong links with Alzheimer's Disease and related dementias

Impact of epigenetics on the clinical management of cancer patients

Study increases understanding of the genetic architecture of dementia risk in African ancestry populations

New methods can advance the development of rapid diagnostics for many infectious diseases

Mutations responsible for common inherited heart condition corrected using CRISPR-Cas9 therapy

Research could pave way for designing more strategically engineered transplants to treat cartilage damage in the joints

Research links mutation that causes Huntington's disease to developmental deficits in the brain's oligodendrocyte cells

Study explores cellular alterations in six distinct neurodegenerative diseases

Huge multi-omic data analysis deciphers colorectal cancer genetics

IU researchers uncover new ways to prevent serious side effects for breast cancer patients

Research estimates the evolutionary origins of functional human microgenes

Research uncovers a new way to boost the effectiveness of RNA therapies

Study shows common synthetic food dye as a potential dietary trigger for IBDs

Analysis finds more than 100 new genetic risk factors strongly linked to colorectal cancer

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo