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New approach can improve the activity of CAR-T cells against blood and solid cancers

A new approach to programing cancer-fighting immune cells called CAR-T cells can prolong their activity and increase their effectiveness against human cancer cells grown in the laboratory and in mice, according to a study by researchers at the Stanford University School of Medicine.

5 Dec 2019

Proteins circulating in the blood could help predict people's age

The carnival worker who tries to guess your age relies on aspects of your appearance, such as your posture and whether any wrinkles emanate from the corners of your eyes and lips. If the carny's guess is more than a few years off, you win a stuffed koala.

5 Dec 2019

Early diagnosis and treatment of chronic inflammation may reduce illness, save lives

Scientists from 22 institutions, including UCLA, are recommending early diagnosis, prevention and treatment of severe chronic inflammation to reduce the risk of chronic disease and death worldwide.

5 Dec 2019

Mount Sinai receives $1 million grant to advance understanding of prostate cancer

The Milton and Carroll Petrie Department of Urology at the Icahn School of Medicine at Mount Sinai has received a $1 million grant from The Arthur M. Blank Family Foundation.

5 Dec 2019

Discovery of protein function opens door to potential therapies for addiction, behavioral disorders

The human brain consists of several intricate networks or "circuits." One such complex circuit, called the "reward circuit," is involved in reward-associated learning, a process in which nerve cell activity changes in response to a "reward" stimulus (something that the brain perceives as a reward).

5 Dec 2019

Adding post-transplant chemotherapy to standard treatment improves remission of allogeneic transplant patients

Investigators in the Blood and Marrow Transplant Program at Rutgers Cancer Institute of New Jersey compared outcomes for patients having undergone allogeneic stem cell transplant when post-transplant cyclophosphamide (PCy, a type of chemotherapy) was added as part of standard treatment to prevent disease through an immune response (immunoprophylaxis) than if this standard treatment was given alone.

5 Dec 2019

Overabundance of novel gene in aggressive form of ovarian cancer may serve as prognostic tool

Investigators at Rutgers Cancer Institute of New Jersey have determined that an overabundance of a novel gene known as ADNP in an aggressive form of ovarian cancer may serve as a prognostic tool.

5 Dec 2019

Prenatal screening for hemoglobinopathies different in OBGYN practices and family medicine

Sickle cell disease is one of the most common inherited red blood cell disorders, yet many are not aware of their carrier status (Treadwell, J Nat Med Assoc, 2006), which can lead to confusion around pregnancy and newborn diagnosis.

5 Dec 2019

Pharma’s take on the Pelosi drug-pricing bill: Fair warning or fearmongering?

House Speaker Nancy Pelosi's flagship proposal to curb prescription drug prices, the "Lower Drug Costs Now Act" - H.R. 3 - could come up for a vote in the chamber this month.

5 Dec 2019

As his wife’s caregiver, a doctor discovers what’s missing at health care’s core

Caring for someone with a serious illness stretches people spiritually and emotionally, often beyond what they might have thought possible.

5 Dec 2019

A major step toward preventing GvHD in patients receiving bone marrow transplants

A drug used for rheumatoid arthritis has moved a step closer to FDA approval for a desperately needed new use.

4 Dec 2019

The 2019 ACR/EULAR Classification Criteria for IgG4-Related Disease released

The American College of Rheumatology and the European League Against Rheumatism released the 2019 ACR/EULAR Classification Criteria for IgG4-Related Disease. It is the first criteria developed specifically for this recently recognized disease.

4 Dec 2019

FDA-approved drug repairs gut leakiness associated with ulcerative colitis

A research team led by biomedical scientists at the University of California, Riverside, has found that a drug approved by the FDA to treat rheumatoid arthritis and ulcerative colitis can repair permeability defects in the gut's epithelium.

4 Dec 2019

Study highlights the need to adhere to more uniform diagnostic criteria for rare lymphoma

In what is believed to be one of the largest studies of a rare disorder known as primary cutaneous gamma delta T-cell lymphoma, Rutgers Cancer Institute of New Jersey investigators and other collaborators examined characteristics, treatment patterns and outcomes of the disease, and determined accurate diagnosis of the disease requires ongoing analysis.

4 Dec 2019

New discovery may bring scientists a step closer to developing hearing loss treatments

A new discovery from a team led by Massachusetts Eye and Ear researchers may bring scientists a step closer to developing treatments that regrow the lost cells that cause hearing loss.

4 Dec 2019

Norfolk dermatologist honored for leadership and increasing accessibility for patients

The American Academy of Dermatology has honored board-certified dermatologist Abby Van Voorhees, MD, FAAD, as a Patient Care Hero for her leadership at the Rapid Access Clinic at the Eastern Virginia Medical School Dermatology Practice in Norfolk, Va.

4 Dec 2019

Less access to specialists associated with higher death, hospitalization rates among rural patients

Residents of rural areas are more likely to be hospitalized and to die than those who live in cities primarily because they lack access to specialists, recent research found.

3 Dec 2019

Eating whole fruit could reduce blood pressure for both men and women

University of Delaware researchers have some good news and some bad news that could help you in those critical, decisive moments.

3 Dec 2019

Using genomics to identify promising novel treatment for lymphatic filariasis

Using innovative RNA sequencing techniques, researchers at the University of Maryland School of Medicine Institute for Genome Sciences identified a promising novel treatment for lymphatic filariasis, a disabling parasitic disease that is difficult to treat.

3 Dec 2019

Researchers awarded $250,000 grant to study tumor microenvironment in lung cancer

Fueling exploration by investigators who collaborate under a research consortium partnership as recognized by the National Cancer Institute, between Rutgers Cancer Institute of New Jersey and Princeton University, the GO2 Foundation for Lung Cancer has awarded $250,000 toward the identification and development of novel strategies to address treatment resistance in non-small cell lung cancer.

3 Dec 2019

Medical School News and Research

New approach can improve the activity of CAR-T cells against blood and solid cancers

Proteins circulating in the blood could help predict people's age

Early diagnosis and treatment of chronic inflammation may reduce illness, save lives

Mount Sinai receives $1 million grant to advance understanding of prostate cancer

Discovery of protein function opens door to potential therapies for addiction, behavioral disorders

Adding post-transplant chemotherapy to standard treatment improves remission of allogeneic transplant patients

Overabundance of novel gene in aggressive form of ovarian cancer may serve as prognostic tool

Prenatal screening for hemoglobinopathies different in OBGYN practices and family medicine

Pharma’s take on the Pelosi drug-pricing bill: Fair warning or fearmongering?

As his wife’s caregiver, a doctor discovers what’s missing at health care’s core

A major step toward preventing GvHD in patients receiving bone marrow transplants

The 2019 ACR/EULAR Classification Criteria for IgG4-Related Disease released

FDA-approved drug repairs gut leakiness associated with ulcerative colitis

Study highlights the need to adhere to more uniform diagnostic criteria for rare lymphoma

New discovery may bring scientists a step closer to developing hearing loss treatments

Norfolk dermatologist honored for leadership and increasing accessibility for patients

Less access to specialists associated with higher death, hospitalization rates among rural patients

Eating whole fruit could reduce blood pressure for both men and women

Using genomics to identify promising novel treatment for lymphatic filariasis

Researchers awarded $250,000 grant to study tumor microenvironment in lung cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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