Trauma News and Research

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Clinical study demonstrates effectiveness of vismodegib in treating BCNS

A revolutionary clinical study has demonstrated the effectiveness of a new drug, vismodegib, in dramatically shrinking and preventing the formation of basal cell skin cancers - the most common cancer in the United States - in patients with basal cell nevus syndrome (BCNS), a rare genetic condition that causes hundreds to thousands of skin cancers primarily treated by surgical removal.

7 Jun 2012

Appropriate CT scans may save and extend lives of children

The American College of Radiology (ACR) urges that results of a study (Pearce et al) to be published in the Lancet regarding radiation risk from pediatric computed tomography (CT) scans should not keep parents from getting needed medical imaging care for their children, but should be discussed with their physician and factored into their shared decision making before an imaging scan is performed.

7 Jun 2012

Ultra-sensitive imaging test can demonstrate link between TBI and PTSD

Even when brain injury is so subtle that it can only be detected by an ultra-sensitive imaging test, the injury might predispose soldiers in combat to post-traumatic stress disorder, according to a University of Rochester Medical Center study.

7 Jun 2012

Four live cases using Toshiba's Infinix-i vascular X-ray systems to be showcased at NCVH

Enabling physicians to transition between cardiac and peripheral work seamlessly during a single procedure, Toshiba America Medical Systems, Inc.'s Infinix-i vascular X-ray systems facilitate better physician workflow and support improved patient care.

6 Jun 2012

UCSF's ACT program helps amputees reach their athletic goals

Carlos Gonzalez stands out from an athletic group gathered on a grassy field at the UCSF Mission Bay campus. The gregarious 32-year-old sports a stylish fauxhawk and walks with a confident yet understated swagger. He's training to become a mixed martial arts (MMA) fighter.

6 Jun 2012

D-cycloserine may increase response to PTSD psychotherapy

Posttraumatic stress disorder (PTSD) is among the most common, distressing, and disabling medical consequences of combat or other extremely stressful life events. The first-line treatment for PTSD is exposure therapy, a type of behavioral therapy where patients confront their fears in a safe environment. Although it is an effective treatment, many patients still experience symptoms after treatment and there is a relatively high drop-out rate.

5 Jun 2012

Chatham, Baxter partner to develop and commercialize hemophilia B gene therapy treatment

Baxter International Inc. today announced that it has entered into an exclusive global agreement with Chatham Therapeutics, LLC, an affiliate of Asklepios BioPharmaceutical, Inc. (AskBio), for the development and commercialization of potential treatments for hemophilia B utilizing Chatham's gene therapy technology.

From Baxter International Inc. 5 Jun 2012

Regular and moderate exercise most beneficial for cardiovascular health

Micah True, legendary ultra-marathoner, died suddenly while on a routine 12-mile training run March 27, 2012. The mythic Caballo Blanco in the best-selling book, Born to Run, True would run as far as 100 miles in a day. On autopsy his heart was enlarged and scarred; he died of a lethal arrhythmia (irregularity of the heart rhythm). Although speculative, the pathologic changes in the heart of this 58 year-old veteran extreme endurance athlete may have been manifestations of "Phidippides cardiomyopathy," a condition caused by chronic excessive endurance exercise.

4 Jun 2012

Akron General Medical Center to install Brainsuite iMRI and iCT integrated neurosurgical suites

Brainlab, a manufacturer of software-driven systems for targeted, less-invasive medical treatments, announced today that Akron General Medical Center will install both Brainsuite iMRI and iCT, making it one of only a handful of hospitals in the world to offer both solutions.

2 Jun 2012

HealthSouth to build comprehensive physical rehabilitation hospital in greater Orlando

HealthSouth Corporation today announced it has received permission from the state to proceed with building a comprehensive physical rehabilitation hospital in the greater Orlando, Fla., market. The 50-bed hospital will provide comprehensive physical rehabilitation to patients who have experienced stroke, trauma, brain and orthopedic injuries or other major illness or injuries.

2 Jun 2012

Exercise reduces expression of cytokines and alleviates neuropathic pain

Exercise helps to alleviate pain related to nerve damage (neuropathic pain) by reducing levels of certain inflammation-promoting factors, suggests an experimental study in the June issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society (IARS).

2 Jun 2012

ENTA announces availability of first non-invasive oral cancer prevention test

Oral cancer is one of the few cancers still on the rise, claiming the lives of as many Americans as melanoma and has shown a recent increase in young, non-smokers. The important news is that oral cancer can now be prevented.

2 Jun 2012

Lilly, Kowa announce results from PREVAIL U.S. study

Kowa Pharmaceuticals America, Inc. and Eli Lilly and Company today announced results of the PREVAIL U.S. study (Pitavastatin compaREd with praVAstatin In Lowering LDL-C in the U.S.) which evaluated the efficacy of LIVALO (pitavastatin) 4 mg compared with pravastatin 40 mg in reducing low-density lipoprotein cholesterol (LDL-C), the primary endpoint, as well as effects on other lipid parameters and lipoprotein particles in adult patients with primary hyperlipidemia or mixed dyslipidemia.

2 Jun 2012

Amarantus to announce results from preclinical study of new protein therapy for TBI

Rainbow BioSciences, the biotech subsidiary of Rainbow Coral Corp., announced today that its latest joint venture target, Amarantus BioSciences, Inc., expects to announce the results of a preclinical study evaluating the potential of its new protein therapy as a treatment for Traumatic Brain Injury (TBI).

2 Jun 2012

College undergraduates less upset than expected by questionnaires about sex, trauma

Research on sex and trauma faces an ethical dilemma: how can we find out more about the effects of such psychologically sensitive topics without hurting the people who participate in the study?

1 Jun 2012

JSUMC completes first procedure with TAVR

Jersey Shore University Medical Center proudly announces the completion of its first procedure with the Transcatheter Aortic Valve Replacement (TAVR), the latest minimally-invasive, life-saving innovation for non-operative patients with critical aortic stenosis.

1 Jun 2012

RXi’s RXI-109 IND receives FDA clearance to proceed into clinical trials

RXi Pharmaceuticals Corporation today announced that it has received clearance for its investigational new drug application (IND) from the U.S. Food and Drug Administration (FDA) to initiate clinical trials with RXI-109, a self-delivering RNAi compound that selectively targets Connective Tissue Growth Factor.

1 Jun 2012

UCSB creates synthetic platelets for various biomedical applications

Synthetic platelets have been developed by UC Santa Barbara researchers, in collaboration with researchers at Scripps Research Institute and Sanford-Burnham Institute in La Jolla, Calif. Their findings are published in the journal Advanced Materials in a paper titled "Platelet Mimetic Particles for Targeting Thrombi in Flowing Blood."

31 May 2012

Exendin-4 significantly minimizes damage in TBI animal models

Although the death toll is relatively low for people who suffer from traumatic brain injury (TBI), it can have severe, life-long consequences for brain function. TBI can impair a patient's mental abilities, impact memory and behavior, and lead to dramatic personality changes. And long-term medical treatment carries a high economic cost.

30 May 2012

ESRD patients with diabetes may benefit from Baxter’s low-glucose PD regimen

Baxter International Inc. today announced results from two large, international multicenter trials demonstrating that a low glucose peritoneal dialysis (PD) regimen favorably impacted metabolic measures important for end-stage renal disease (ESRD) patients with diabetes, including blood glucose (sugar) control and selected lipids.

From Baxter International Inc. 28 May 2012