Immune Response News and Research

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Stem cell vaccine helps protect mice against numerous cancers, finds study

Lab mice injected with inactivated induced pluripotent stem cells (iPSCs) displayed a significant immune response against lung, breast, and skin cancers. The vaccine also prevented relapses in animals with removed tumors.

16 Feb 2018

CAR-T therapy saves life of cancer researcher

About a dozen years ago, Dr. Woodring Wright, a UT Southwestern Professor of Cell Biology, sneezed. It broke one of his vertebrae, the interlocking bones that make up the spinal column.

14 Feb 2018

Oncolytic virus alerts the immune system to attack tumors

A new UC San Francisco study has shown that a cancer-killing virus currently in clinical trials may function as a cancer vaccine - in addition to killing some cancer cells directly, the virus alerts the immune system to the presence of a tumor, triggering a powerful, widespread immune response that kills cancer cells far outside the virus-infected region.

14 Feb 2018

Histamine levels substantially higher in homes infested by bed bugs, study shows

New research findings could turn perceptions of the already despised bed bug from nuisance pest into medically important threat.

13 Feb 2018

Study reports longer survival for obese men with metastatic melanoma

Obese patients with metastatic melanoma who are treated with targeted or immune therapies live significantly longer than those with a normal body mass index, investigators report in a study published in Lancet Oncology of 1,918 patients in six independent clinical cohorts.

13 Feb 2018

Researchers shine new light on hookworm-malaria co-infections

A study released today from an international team of researchers shines new light on "co-infections," infectious diseases that attack the immune system simultaneously.

9 Feb 2018

Molecular 'magnets' could help develop better immunotherapies for cancer patients

Chemicals that attract specialized immune cells toward tumors could be used to develop better immunotherapies for cancer patients, according to new research published in Cell.

9 Feb 2018

Researchers develop safe, potent mRNA vaccine adjuvants that can elicit effective immune response

Production of conventional vaccines, which involves the use of live-attenuated or purified protein subunits of pathogens, is a long and complex process. Nucleic acid vaccines are safer alternatives, and allow easy adjustment of antigen to target specific pathogens.

9 Feb 2018

Human antibodies against malaria parasite can prevent spread of disease

Malaria is a disease that spreads incredibly efficiently. The antimalarial medicines that are currently used cannot do much to stop this, because the parasites remain in the patient's blood for a long time after treatment.

8 Feb 2018

Special protein improves survival and lung function of mice with influenza, study shows

GM-CSF, a protein that modifies the immune response to the flu, may also help reduce lung inflammation and improve survival during influenza, according to Penn State researchers.

8 Feb 2018

Vitamin A-enriched cattle fodder is the key to protect against cow's milk allergy

A real milk allergy occurs in about three to five percent of European children and more rarely in adults. The disease is different from lactose intolerance, in which a lack of the enzyme lactase results in the inability to properly break down lactose, a sugar found in milk products.

6 Feb 2018

Researchers report technical advances in production of HIV vaccines

Research on HIV over the past decade has led to many promising ideas for vaccines to prevent infection by the AIDS virus, but very few candidate vaccines have been tested in clinical trials.

6 Feb 2018

Discovery opens new doors to developing vaccines for preventing staph skin infections

After years of investigation, researchers at Johns Hopkins, the University of California, Davis, and the National Institute of Allergy and Infectious Diseases have discovered how the immune system might protect a person from recurrent bacterial skin infections caused by Staphylococcus aureus (staph).

6 Feb 2018

Researchers receive major boost to explore long-standing paradigm in endocrinology

A team of researchers at the University of California, Riverside, seeking to upend a long-held theory explaining how hormones freely enter and exit cells, has received a major boost in the form of a $1 million award from the W. M. Keck Foundation.

5 Feb 2018

Moffitt study identifies new drug target that may reduce GVHD risk

Stem cell transplants can cure patients with high-risk leukemia or lymphoma. Graft-versus-host disease is a potentially life-threatening side effect that occurs when the donor's immune cells attack the recipient's normal tissues.

5 Feb 2018

Research uncovers how viruses outsmart the immune system

How do viruses that cause chronic infections, such as HIV or hepatitis c virus, manage to outsmart their hosts' immune systems? The answer to that question has long eluded scientists, but new research from McGill University has uncovered a molecular mechanism that may be a key piece of the puzzle. The discovery could provide new targets for treating a wide range of diseases.

5 Feb 2018

Novel grape-derived compounds could be developed as therapeutic agents for treatment of depression

In a study to be published online February 2 in Nature Communications, scientists from the Icahn School of Medicine at Mount Sinai describe an extensive analysis of novel grape-derived compounds, dihydrocaffeic acid (DHCA) and malvidin-3'-O-glucoside (Mal-gluc),which might be developed as therapeutic agents for the treatment of depression.

2 Feb 2018

Two bacterial species collaborate to drive development of colon cancers

Patients with an inherited form of colon cancer harbor two bacterial species that collaborate to encourage development of the disease, and the same species have been found in people who develop a sporadic form of colon cancer, a study led by a Johns Hopkins Bloomberg~Kimmel Institute for Cancer Immunotherapy research team finds.

1 Feb 2018

Platelets play more important role in the immune system than previously thought

Platelets play a much more important role in our immune system than previously thought, according to a study published by researchers from Université Laval and Centre hospitalier universitaire de Québec Research Center.

1 Feb 2018

Elevated levels of chlorinated lipids linked to lung injury and death in sepsis patients

In a study published in the Journal of Clinical Investigation Insight, Saint Louis University scientists have found that elevated levels of chlorinated lipids are linked to sepsis, lung injury and death. The finding may offer a way to diagnosis and treat sepsis earlier, saving lives and avoiding serious side effects.

31 Jan 2018

Immune Response News and Research

Stem cell vaccine helps protect mice against numerous cancers, finds study

CAR-T therapy saves life of cancer researcher

Oncolytic virus alerts the immune system to attack tumors

Histamine levels substantially higher in homes infested by bed bugs, study shows

Study reports longer survival for obese men with metastatic melanoma

Researchers shine new light on hookworm-malaria co-infections

Molecular 'magnets' could help develop better immunotherapies for cancer patients

Researchers develop safe, potent mRNA vaccine adjuvants that can elicit effective immune response

Human antibodies against malaria parasite can prevent spread of disease

Special protein improves survival and lung function of mice with influenza, study shows

Vitamin A-enriched cattle fodder is the key to protect against cow's milk allergy

Researchers report technical advances in production of HIV vaccines

Discovery opens new doors to developing vaccines for preventing staph skin infections

Researchers receive major boost to explore long-standing paradigm in endocrinology

Moffitt study identifies new drug target that may reduce GVHD risk

Research uncovers how viruses outsmart the immune system

Novel grape-derived compounds could be developed as therapeutic agents for treatment of depression

Two bacterial species collaborate to drive development of colon cancers

Platelets play more important role in the immune system than previously thought

Elevated levels of chlorinated lipids linked to lung injury and death in sepsis patients

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Why use light scattering to analyze proteins and viral vectors?

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