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Malignant mesothelioma diagnosis with an E-nose: an interview with Associate Professor Deborah Yates, UNSW

Malignant mesothelioma is a rare tumor of the pleura which is the lining of the inside of the chest wall. It is highly linked with asbestos exposure.

16 Aug 2012

Combination of exercise and S-nitrosoglutathione improves recovery from stroke

In a study published in the current issue of Restorative Neurology and Neuroscience scientists report that a therapy combining exercise with the neurovascular protective agent S-nitrosoglutathione (GSNO) improved recovery from stroke in a rat model. GSNO is a compound found naturally in the body and it has no known side effects or toxicity.

16 Aug 2012

Diffusion Pharmaceuticals receives new U.S. patents for trans sodium crocetinate

Diffusion Pharmaceuticals LLC, a biotechnology company focused on innovative cancer treatments, today announced that the U.S. Patent and Trademark Office has granted it patent numbers 7919527 and 8030350, entitled "Bipolar Trans Carotenoids Salts and Their Uses" and "Trans Carotenoids, Their Synthesis and Uses," respectively.

16 Aug 2012

Excessive cleanliness may be bad for your health

Research suggests that the antibacterial chemical triclosan, commonly used in personal-care products and antibacterial soaps, may impair the function of cardiac and skeletal muscle.

15 Aug 2012

Spectrum Pharmaceuticals initiates enrollment in Phase 2b ozarelix study for prostate cancer

Spectrum Pharmaceuticals, a biotechnology company with fully integrated commercial and drug development operations with a primary focus in hematology and oncology, today announced initiation of patient enrollment in the second part of the Company's randomized Phase 2 clinical program of ozarelix, a luteinizing hormone-releasing hormone (LHRH) antagonist, in men with prostate cancer for whom hormonal treatment is indicated.

15 Aug 2012

Schizophrenia and the immune system: an interview with Prof Cyndi Shannon Weickert

Schizophrenia is the most disabling disease impacting youth today. It impacts 1% of the total population and typically causes withdrawal from society, loss in IQ, disordered thought and speech, hallucinations and delusions.

14 Aug 2012

Latrepiridine reduces level of at least two neurodegeneration-related proteins in mice

14 Aug 2012

Latrepirdine demonstrates new potential against neurodegenerative conditions

The second of two studies on latrepirdine, recently published in Molecular Psychiatry, demonstrates new potential for the compound in the treatment of Alzheimer's disease, Parkinson's disease, sleep disorders, and other neurodegenerative conditions. An international team led by Mount Sinai School of Medicine scientists found that latrepiridine, known commercially as Dimebon, reduced the level of at least two neurodegeneration-related proteins in mice.

13 Aug 2012

Grapes reduce key risk factors for heart disease in men with metabolic syndrome

Consuming grapes may help protect heart health in people with metabolic syndrome, according to new research published in the Journal of Nutrition. Researchers observed a reduction in key risk factors for heart disease in men with metabolic syndrome: reduced blood pressure, improved blood flow and reduced inflammation. Natural components found in grapes, known as polyphenols, are thought to be responsible for these beneficial effects.

10 Aug 2012

Active Biotech, Teva to commence third Phase III study of laquinimod for RRMS

Teva Pharmaceutical Industries Ltd. and Active Biotech provided today an update on the clinical development program of once-daily oral laquinimod for the treatment of relapsing-remitting multiple sclerosis (RRMS).

9 Aug 2012

Global market value of Alzheimer's disease therapeutics could soar to $8 billion: GEN

The global market value of Alzheimer's disease therapeutics could soar to the $8 billion range once therapeutics are approved that actually change the course of the disease, reports Genetic Engineering & Biotechnology News (GEN).

8 Aug 2012

BioDiem granted European patent for antimicrobial drug

Australian vaccine development company BioDiem Ltd (ASX: BDM) announced today the successful granting of a key European patent for its synthetic antimicrobial compound BDM-I. BDM-I is a novel compound active against a range of pathogenic micro-organisms including bacteria, fungi and protozoa. The patent provides protection around BDM-I as a treatment for vulvovaginitis, a general term for inflammation of the vulva or vagina.

7 Aug 2012

Pendrin a possible new target for diuretic therapy

In patients with fluid overload, inhibition of the chloride-absorbing transporter pendrin and the NaCl co-transporter may provide an effective diuretic regimen without triggering hypokalemia, research suggests.

6 Aug 2012

Aquapharm discovers new antibiotic compound against multi-drug resistant bacteria

A significant discovery in the development of next-generation antibiotics has been made by Scottish biotechnology company Aquapharm.

6 Aug 2012

Common ragweed may induce airways irritation through terpenoids

Allergy to pollen of common ragweed is increasingly affecting patients and is second only to grass pollen in terms of incidence in the general population of many European countries.

6 Aug 2012

Simpler and more accurate way to test for prostate cancer

An undergraduate student's technique for detecting certain metabolites in urine samples could lead to a simpler and more accurate way to test for prostate cancer.

3 Aug 2012

Planarian flatworms now a model system for studying eye development and eye diseases

Planarian flatworms have come under intense study for their renowned ability to regenerate any missing body part, even as adults. But now they may take on a starring role as a model system for studying eye development and eye diseases in vertebrates, including humans.

3 Aug 2012

Strawberry extract protects against UVA rays

An experiment has shown that strawberry extract added to skin cell cultures acts as a protector against ultraviolet radiation as well as increasing its viability and reducing damage to DNA. Developed by a team of Italian and Spanish researchers, the study opens the door to the creation of photoprotective cream made from strawberries.

3 Aug 2012

Drug discovery research at University of Nottingham supported by SPT Labtech

SPT Labtech, global developer and manufacturer of high quality, robust and innovative automated laboratory equipment, is enabling a successful new venture at the University of Nottingham’s Centre for Biomolecular Science, with its comPOUND® sample storage system and comPILER® high throughput, tube-to-plate processing system.

From SPT Labtech 3 Aug 2012

Anacardic acid can rescue some ALS phenotypes in vitro

A research group at the Center for iPS Cell Research and Application (CiRA) at Japan's Kyoto University has successfully recapitulated amyotrophic lateral sclerosis (ALS)-associated abnormalities in motor neurons differentiated from induced pluripotent stem cells (iPSCs) obtained from patients with familial ALS, a late-onset, fatal disorder which is also known for Lou Gehrig's disease. In a drug screening assay using the disease model, the team further found that the chemical compound anacardic acid can rescue some ALS phenotypes in vitro.

3 Aug 2012

Compound News and Research

Malignant mesothelioma diagnosis with an E-nose: an interview with Associate Professor Deborah Yates, UNSW

Combination of exercise and S-nitrosoglutathione improves recovery from stroke

Diffusion Pharmaceuticals receives new U.S. patents for trans sodium crocetinate

Excessive cleanliness may be bad for your health

Spectrum Pharmaceuticals initiates enrollment in Phase 2b ozarelix study for prostate cancer

Schizophrenia and the immune system: an interview with Prof Cyndi Shannon Weickert

Latrepiridine reduces level of at least two neurodegeneration-related proteins in mice

Latrepirdine demonstrates new potential against neurodegenerative conditions

Grapes reduce key risk factors for heart disease in men with metabolic syndrome

Active Biotech, Teva to commence third Phase III study of laquinimod for RRMS

Global market value of Alzheimer's disease therapeutics could soar to $8 billion: GEN

BioDiem granted European patent for antimicrobial drug

Pendrin a possible new target for diuretic therapy

Aquapharm discovers new antibiotic compound against multi-drug resistant bacteria

Common ragweed may induce airways irritation through terpenoids

Simpler and more accurate way to test for prostate cancer

Planarian flatworms now a model system for studying eye development and eye diseases

Strawberry extract protects against UVA rays

Drug discovery research at University of Nottingham supported by SPT Labtech

Anacardic acid can rescue some ALS phenotypes in vitro

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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