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From Discovery Biology to ELRIG Chair: A Conversation with Melanie Leveridge

In this interview, we speak with Melanie Leveridge, Vice President of Discovery Biology at AstraZeneca and Chair of the Board for ELRIG UK, to discuss her extensive career in the pharmaceutical industry, her role in fostering scientific innovation, and her vision for ELRIG's future.

From ELRIG (UK) Ltd. 13 Jun 2024

Synthetic cell mimics immune response via symmetry breaking

In a feat aimed at understanding how cells move and creating new ways to shuttle drugs through the body, scientists at Johns Hopkins Medicine say they have built a minimal synthetic cell that follows an external chemical cue and demonstrates a governing principle of biology called "symmetry breaking."

12 Jun 2024

Germ cells drive sex-dependent lifespan differences in vertebrate animals

Women live longer than men. This isn't unique to humans, either; we see this trend in a wide range of other animals.

12 Jun 2024

Integration of genomics, epigenomics, and transcriptomics in understanding Alzheimer's pathogenesis

With the advent of new omics technologies in recent years, there has been a deluge of complex, high-dimensional data on Alzheimer's disease (AD).

12 Jun 2024

Long-read RNA sequencing reveals novel insights into alternative splicing and disease genetics

Tokyo Medical and Dental University (TMDU) researchers harness long-read RNA sequencing to decode genetic intricacies and disease links.

12 Jun 2024

UC San Diego engineers develop algae-based microrobots for lung cancer treatment

Engineers at the University of California San Diego have developed microscopic robots, known as microrobots, capable of swimming through the lungs to deliver cancer-fighting medication directly to metastatic tumors.

12 Jun 2024

Nasal microbiota composition predicts sepsis with high accuracy in ICU settings

The nasal microbiota of intensive care unit (ICU) patients effectively distinguishes sepsis from non-septic cases and outperforms analyzing the gut microbiota to predict sepsis, according to a new study published in Microbiology Spectrum, a journal of the American Society for Microbiology.

12 Jun 2024

Enhancing CAR-T cell therapy with biodegradable scaffolds

CAR-T cell therapies are transforming the treatment of previously incurable blood cancers. Six approved CAR-T products have been administered to more than 20,000 people, and more than 500 clinical trials are underway.

12 Jun 2024

Differing definitions of iron deficiency lead to divergent estimates of prevalence, study finds

How different ways of defining iron deficiency (ID) impact the prevalence estimates of this common disorder among women.

12 Jun 2024

UD researchers pioneer universal, economical method for proteomics sample preparation

Proteins are workhorses that carry out most of the biological functions in our cells. While the genes we inherit from our parents, our so-called genome, are fixed and usually remain unchanged throughout our lives, proteins in our bodies are constantly changing, as we age, under different health conditions and upon stimulation, such as with medical treatment.

11 Jun 2024

Antioxidants combat high-fat diet-induced female reproductive issues, study reveals

Researchers in Italy review how antioxidants from biological matrices can protect against reproductive issues caused by high-fat diets in women.

11 Jun 2024

Study reveals exploitation mechanism of virus-related nanoparticles for bacterial proliferation

Viruses are ubiquitous in the environment, and organisms have developed various mechanisms to counter their threat.

11 Jun 2024

Mount Sinai researchers use AI to identify 17 key genes in heart disease

Using an advanced artificial intelligence tool, researchers at the Icahn School of Medicine at Mount Sinai have identified rare coding variants in 17 genes that shed light on the molecular basis of coronary artery disease (CAD), the leading cause of morbidity and mortality worldwide.

11 Jun 2024

Newcells Biotech strengthens executive and US team with key appointments

Dr Valeria Chichagova appointed as Director of Technology, Dr Colin Brown as Chief Scientific Officer, and Professor Lyle Armstrong as Scientific Advisor.

From Newcells Biotech 11 Jun 2024

Breathing New Life into Diagnostics: Plasmion's SICRIT® Technology

Revolutionizing Non-Invasive Diagnostics with Plasmion’s SICRIT Breath Analysis.

From Plasmion 11 Jun 2024

Understanding Crohn's disease through 'mini-gut' models

Cambridge scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an important role in the disease and how it presents in patients.

10 Jun 2024

UC Davis pioneers advanced PET imaging to monitor lung cancer treatment

Lung cancer can advance quickly. Once a person starts treatment, it is vital to know if that treatment is working or if the patient should be switched to a different treatment.

10 Jun 2024

Transforming antibody drug discovery with Epitope Binning-seq

Monoclonal antibodies are crucial therapeutics due to their high specificity and binding affinity for epitopes (the precise sites where an antibody attaches itself to an antigen, triggering an immune response).

10 Jun 2024

Particle Measuring Systems and Pharma Integration Introduce the BioCapt® Single-Use AutoM Microbial Impactor for Automated Microbial Air Sampling

Particle Measuring Systems (PMS), a global leader in contamination monitoring, and Pharma Integration, a company that specializes in innovative robotic solutions for small volume fill-finishing for next generation injectable drugs are proud to announce the launch of the BioCapt Single-Use AutoM Microbial Impactor.

From Particle Measuring Systems 10 Jun 2024

Unveiling Pseudomonas aeruginosa's lung invasion tactics with human lung microtissues

How do pathogens invade the lungs? Using human lung microtissues, a team at the Biozentrum of the University of Basel has uncovered the strategy used by a dangerous pathogen.

10 Jun 2024

Technology News and Research

From Discovery Biology to ELRIG Chair: A Conversation with Melanie Leveridge

Synthetic cell mimics immune response via symmetry breaking

Germ cells drive sex-dependent lifespan differences in vertebrate animals

Integration of genomics, epigenomics, and transcriptomics in understanding Alzheimer's pathogenesis

Long-read RNA sequencing reveals novel insights into alternative splicing and disease genetics

UC San Diego engineers develop algae-based microrobots for lung cancer treatment

Nasal microbiota composition predicts sepsis with high accuracy in ICU settings

Enhancing CAR-T cell therapy with biodegradable scaffolds

Differing definitions of iron deficiency lead to divergent estimates of prevalence, study finds

UD researchers pioneer universal, economical method for proteomics sample preparation

Antioxidants combat high-fat diet-induced female reproductive issues, study reveals

Study reveals exploitation mechanism of virus-related nanoparticles for bacterial proliferation

Mount Sinai researchers use AI to identify 17 key genes in heart disease

Newcells Biotech strengthens executive and US team with key appointments

Breathing New Life into Diagnostics: Plasmion's SICRIT® Technology

Understanding Crohn's disease through 'mini-gut' models

UC Davis pioneers advanced PET imaging to monitor lung cancer treatment

Transforming antibody drug discovery with Epitope Binning-seq

Particle Measuring Systems and Pharma Integration Introduce the BioCapt® Single-Use AutoM Microbial Impactor for Automated Microbial Air Sampling

Unveiling Pseudomonas aeruginosa's lung invasion tactics with human lung microtissues

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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