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New link between two important products of nitric oxide discovered

Ever since three US-based researchers working independently unveiled the role of nitric oxide in mediating blood vessel dilation, endothelial cell contraction and smooth muscle relaxation, their discoveries have served as a basis for novel treatments for high blood pressure and erectile dysfunction, among other conditions.

4 Oct 2019

New defensive mechanism against bacterial wound infections discovered

Wound inflammation which results in impaired wound healing can have serious consequences for patients. Researchers from Charité - Universitätsmedizin Berlin have discovered a new defensive mechanism which enables our skin to actively kill bacteria.

4 Oct 2019

Men should stay alcohol-free for at least six months before conception

A new study has revealed that men hoping to conceive should stop drinking for at least six months before to prevent congenital heart diseases.

4 Oct 2019

New anticancer molecule shows therapeutic activity in preclinical models of various cancer types

A novel anticancer molecule created by researchers at The Wistar Institute showed therapeutic activity in preclinical models of various cancer types.

3 Oct 2019

UCR biochemist receives grant to develop novel lead compound to treat breast cancer

A biochemist at the University of California, Riverside, has received a grant from the Congressionally Directed Medical Research Programs, or CDMRP, of the U.S. Department of Defense to develop a novel lead compound to treat breast cancer, the second most commonly diagnosed cancer among American women.

3 Oct 2019

Innovative compound kills cancer cells, minimizes damage to normal tissues

Most of the current clinical anti-tumor drugs used in chemotherapy move around in the patient's blood after intake and are unable to pinpoint the targeted tumor. As a result, while killing the tumor cells, the healthy cells may also be killed as "collateral damage", leading to undesired side effects.

3 Oct 2019

Researchers elucidate enzymes that control long-term memory, learning process in the brain

When we first purchase a smart phone, all of our settings and applications are the same. But as time passes, everyone's phones will change drastically as we adapt them to our own individual needs and preferences. In the same way, our memories and life experiences are loaded into our brains, making one person unique from another.

2 Oct 2019

CAR T-cell therapy may be effective in killing solid tumor cells

There is now a multitude of therapies to treat cancer, from chemotherapy and radiation to immunotherapy and small molecule inhibitors. Chemotherapy is still the most widely used cancer treatment, but chemotherapy attacks all the rapidly dividing cells that it locates within the body, whether they're ultimately harmful or beneficial.

2 Oct 2019

Fighting for Change: Detecting Fraudulent Honey using NMR

In this interview, Peter Awram discusses the benefits of NMR spectroscopy as an analytical technique for the honey industry, in the fight against fraud.

From Bruker BioSpin Group 2 Oct 2019

Chemicals used for pharmaceuticals could be made more sustainably by new catalysts

High value chemicals used to make pharmaceuticals could be made much cheaper and quicker thanks to a series of new catalysts made by scientists at the University of Warwick in collaboration with GoldenKeys High-Tech Co., Ltd. in China.

1 Oct 2019

UK-based scientists aim to make infant formula more like human breast milk

UK-based scientists have engineered plants to produce an oil that mimics the chemical structure of human milk fat, a major component of breast milk.

1 Oct 2019

Wistar researcher receives NIH Director's Award to study link between diet, alcohol use and cancer

The National Institutes of Health today announced that Zachary T. Schug, Ph.D., assistant professor in the Molecular & Cellular Oncogenesis Program at The Wistar Institute, was awarded the prestigious NIH Director's New Innovator Award in support of his research on the link between a high sugar/fat diet, alcohol use and cancer.

1 Oct 2019

Cannabis: CBD vs THC causes lower psychiatric side-effects

A study has revealed how cannabidiol works against tetrahydrocannabinol to prevent psychiatric side effects.

1 Oct 2019

Why granny’s herbs work to lower high blood pressure

A study from the University of California, Irvine, explains a hitherto unknown mechanism of action for bioactive molecules in commonly used plant-based folk medicines like fennel, camomile and lavender that are used to lower the blood pressure.

1 Oct 2019

University of Georgia signs contract with NIH to develop advanced influenza vaccine

The University of Georgia has signed a contract with the National Institutes of Health for an initial award of $8 million to develop a new, more advanced influenza vaccine designed to protect against multiple strains of influenza virus in a single dose.

30 Sep 2019

Study shows how cannabidiol blocks the psychiatric side-effects of THC

Researchers at Western University have shown for the first time the molecular mechanisms at work that cause cannabidiol, or CBD, to block the psychiatric side-effects caused by tetrahydrocannabinol, the main psychoactive chemical in cannabis.

30 Sep 2019

Diabetic mice benefit from increased ‘good’ cholesterol levels

A new study has looked into the artificial increase in the level of 'good' cholesterol and its link to the reversal of atherosclerosis in arteries.

30 Sep 2019

Using X-ray-nanoparticle interactions for improved radiation therapy

A new study has indicated a new way to deliver locally aggressive radiation therapy in cancer, using the element gadolinium.

30 Sep 2019

A new method to distinguish benign and cancerous skin moles

A new study has reported a cost-effective, more accurate, and less invasive way to diagnose cancerous melanoma cells in skin tumors.

30 Sep 2019

RNA Targeted Small Molecules: Finally Drug the “Undruggable” RNA

At a time when the previously untapped drug discovery opportunity promised within RNA opens up, the 2nd RNA- Targeted Drug Discovery Summit returns to reunite the leading minds from large pharma, innovative biotech and KOLs of academia to overcome unique discovery and development challenges associated with novel RNA targeted small molecule therapeutics and achieve their seemingly limitless potential.

From RNA-Targeted Drug Discovery Summit 30 Sep 2019